橘 皮Orange peelWord文件下载.docx
《橘 皮Orange peelWord文件下载.docx》由会员分享,可在线阅读,更多相关《橘 皮Orange peelWord文件下载.docx(9页珍藏版)》请在冰豆网上搜索。
--------------------------------------------------------------------------------
RutaceaecitrusCitrustangerinaHort.etTanakaC.erythrosaTanakaorcumquatandothercitruspeel.Acrid,bitterandwarminnature.Inspleenandlung.Function:
reason
Gas,transfer,dampness,phlegm.Indications:
abdominaldistension,poorappetite,vomiting,hiccup,coughandphlegm.Fishandcrabpoison,too.Oraladministration:
decoction,3~9g;
orintothepill,scattered.
[modernresearch]
Mainingredients:
driedtangerinepeelcontainsvolatileoil1.9%~3.5%.Mainlyforthelimonene(Limonene);
therearealphathujene(alpha-Thujene),alphapinene(alpha-Pinene),betapinene(betaPinene),betamyrcene(Beta
Myrcene(Sabine-NE),sabinene),octylaldehyde(Octanal),alphaphellandrene(-Phellandrenealpha),alphaTerpinene(alpha-Terpinene),ellagicacid(p-Cymene)-thyrse,linalool(Linalool),musk
Vanillaphenol(Thymol),citronellaaldehyde(Citronellal)andothercomponents.
Inaddition,hesperidin(Hesperidin),newhesperidin(Neohesperidin),citrus(Tangeretin),flavonoids,citral,beta-glutamyl(beta-Sitosterol),andQiangFulin
(Synephrine)etal.
Pharmacologicalaction:
1.expectorantandantiasthmaticeffect,thevolatileoilcontainedinPericarpiumCitricitriisirritatingexpectoranteffect,themainingredientislimonene.ThefreshproductDecoctionseemstohavebronchiectasis.Tangerinepeel0.02gextract(crudedrug)/mlconcentration,can
Convulsivecontractionofguineapigisolatedfromguineapigscompletelyagainsthistamine.Ithascertaincurativeeffectonbronchialasthma.Theanimalexperimentshowedthatnobiletinintravenously,abronchodilator,strengthwaslessthanthatofammonia
Theophylline,butintravenousinjection,enema,andintragastricadministrationcannotcombatbronchospasmcausedbyhistamine.Theeffectofmethylhesperidinontheisolatedtracheaofguineapigsisverysmall.
2.theeffectsofthedecoctionofPericarpiumCitricitri,ethanolicextractandhesperidinontheheartofisolatedandinvivofrogswerestimulated.Intravenousinjectionofhesperidincanincreasethecontractilityandcardiacoutputintherabbits
Add,butnosignificanteffectonheartrate.Hesperidincontainingoxidationproductscanincreaseheartcontractilityandheartrateinrabbits,whilepureproductsarenoteffective.Methylorangehesperidin40mg/kgwasgivenintravenouslyindogstoreducecoronaryresistanceandincreasecrownsize
Theeffectofpulseflow,loweringbloodpressureandslowingheartrate,butnosignificantinfluenceonmyocardialoxygenconsumption,myocardialoxygenutilizationrateandmyocardialcontractility.
Theintravenousinjectionofdriedtangerinepeelcanincreasethebloodpressureofrabbitsanddogsrapidly.Repeateduseofmedicinedoesnotproducerapidtolerance.Itcanalsoreducethevolumeofcaninekidney,vasoconstrictionofrenalvesselsanddecreaseofurinevolume.Theboostingingredientsofdriedtangerinepeel
Boilingisnotdestroyed,theactiontimeislongerthantheadrenaline,andmorestable.Hesperidinhasnohypotensiveeffectonanesthetizedcatsanddogs,andevenantagonizedthevascularcontractioninducedbyadrenalineperfusioninrabbitears.Theeffectofhesperidinontheperipheralbloodofcats
Tubeshaveshortandobviousexpansion,butpureproductswithoutoxidesareineffective.
PPhesperidinhastheeffectofdecreasingserumcholesterolandreducingandimprovingthemainatheroscleroticlesioninrabbitswithexperimentalhyperlipemia.
Orangepeelpowderformiceandrabbitsbygavage,shortenthebleedingtimeandclottingtimeeffect,bakedintocharcoalpowdermedicinetoshortenthecoagulationtimeeffectofcrudedrughasbeenenhanced.
3.theeffectofthedecoctionofdriedtangerinepeelonthemovementofthesmallintestineinmiceandrabbitswasinhibitedbyintravenousinjection,andthegastricmotilityofanesthetizeddogs,gastrointestinalandanesthetizedrabbitsandanesthetizedrabbitswasalsoinhibitedbyintravenousinjection.Thiseffectisgreater
Epinephrineisweakbutpersistent.Theexperimentprovedthatthedriedtangerinepeelhastheactionofresistingacetylcholinetotherabbitintestine,buttheeffectofthetangerinepeeloninhibitingtherabbitintestinecanbealsoaffectedbyacetylcholine.Orangepeelisalsoreferredtopilocarpineorbariumchloride
Thespasticcontractionoftheintestinaltracthasanantagonisticeffect.
Itissuggestedthatthedirectinhibitionofsmoothmuscleofintestinebytangerinepeelisitsmainwayofrelievingspasm.
Methylhesperidin0.5to1mg/mlcouldcompletelyinhibitthemovementofisolatedileuminguineapigs,butonlyslightspasmofintestinalmusclespasmcausedbyacetylcholine,histamineorbariumchloride.Italsoinhibitedthera