橘 皮Orange peelWord文件下载.docx

1、-Rutaceae citrus Citrus tangerina Hort. et Tanaka C. erythrosa Tanaka or cumquat and other citrus peel. Acrid, bitter and warm in nature. In spleen and lung. Function: reasonGas, transfer, dampness, phlegm. Indications: abdominal distension, poor appetite, vomiting, hiccup, cough and phlegm. Fish an

2、d crab poison, too. Oral administration: decoction, 3 9g; or into the pill, scattered.modern researchMain ingredients: dried tangerine peel contains volatile oil 1.9% 3.5%. Mainly for the limonene （Limonene）; there are alpha thujene （alpha -Thujene）, alpha pinene （alpha -Pinene）, beta pinene （beta P

3、inene）, beta myrcene （BetaMyrcene （Sabine- NE）, sabinene）, octyl aldehyde （Octanal）, alpha phellandrene （-Phellandrene alpha）, alpha Terpinene （alpha -Terpinene）, ellagic acid （p-Cymene） - thyrse, linalool （Linalool）, muskVanilla phenol （Thymol）, citronella aldehyde （Citronellal） and other component

4、s.In addition, hesperidin （Hesperidin）, new hesperidin （Neohesperidin）, citrus （Tangeretin）, flavonoids, citral, beta - glutamyl （beta -Sitosterol）, and Qiang Fulin（Synephrine） et al.Pharmacological action:1. expectorant and antiasthmatic effect, the volatile oil contained in Pericarpium Citri citri

5、 is irritating expectorant effect, the main ingredient is limonene. The fresh product Decoction seems to have bronchiectasis. Tangerine peel 0.02g extract （crude drug） /ml concentration, canConvulsive contraction of guinea pig isolated from guinea pigs completely against histamine. It has certain cu

6、rative effect on bronchial asthma. The animal experiment showed that nobiletin intravenously, a bronchodilator, strength was less than that of ammoniaTheophylline, but intravenous injection, enema, and intragastric administration can not combat bronchospasm caused by histamine. The effect of methyl

7、hesperidin on the isolated trachea of guinea pigs is very small.2. the effects of the decoction of Pericarpium Citri citri, ethanolic extract and hesperidin on the heart of isolated and in vivo frogs were stimulated. Intravenous injection of hesperidin can increase the contractility and cardiac outp

8、ut in the rabbitsAdd, but no significant effect on heart rate. Hesperidin containing oxidation products can increase heart contractility and heart rate in rabbits, while pure products are not effective. Methyl orange hesperidin 40mg/kg was given intravenously in dogs to reduce coronary resistance an

9、d increase crown sizeThe effect of pulse flow, lowering blood pressure and slowing heart rate, but no significant influence on myocardial oxygen consumption, myocardial oxygen utilization rate and myocardial contractility.The intravenous injection of dried tangerine peel can increase the blood press

10、ure of rabbits and dogs rapidly. Repeated use of medicine does not produce rapid tolerance. It can also reduce the volume of canine kidney, vasoconstriction of renal vessels and decrease of urine volume. The boosting ingredients of dried tangerine peelBoiling is not destroyed, the action time is lon

11、ger than the adrenaline, and more stable. Hesperidin has no hypotensive effect on anesthetized cats and dogs, and even antagonized the vascular contraction induced by adrenaline perfusion in rabbit ears. The effect of hesperidin on the peripheral blood of catsTubes have short and obvious expansion,

12、but pure products without oxides are ineffective.P P hesperidin has the effect of decreasing serum cholesterol and reducing and improving the main atherosclerotic lesion in rabbits with experimental hyperlipemia.Orange peel powder for mice and rabbits by gavage, shorten the bleeding time and clottin

13、g time effect, baked into charcoal powder medicine to shorten the coagulation time effect of crude drug has been enhanced.3. the effect of the decoction of dried tangerine peel on the movement of the small intestine in mice and rabbits was inhibited by intravenous injection, and the gastric motility

14、 of anesthetized dogs, gastrointestinal and anesthetized rabbits and anesthetized rabbits was also inhibited by intravenous injection. This effect is greaterEpinephrine is weak but persistent. The experiment proved that the dried tangerine peel has the action of resisting acetylcholine to the rabbit

15、 intestine, but the effect of the tangerine peel on inhibiting the rabbit intestine can be also affected by acetylcholine. Orange peel is also referred to pilocarpine or barium chlorideThe spastic contraction of the intestinal tract has an antagonistic effect.It is suggested that the direct inhibiti

16、on of smooth muscle of intestine by tangerine peel is its main way of relieving spasm.Methyl hesperidin 0.5 to 1mg/ml could completely inhibit the movement of isolated ileum in guinea pigs, but only slight spasm of intestinal muscle spasm caused by acetylcholine, histamine or barium chloride. It also inhibited the ra