共享医学SCI论文经典句子汇总.docx

共享医学SCI论文经典句子汇总.docx

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共享医学SCI论文经典句子汇总

医学生物学SCI论文经典句子汇编

Title

要求简练，精确

_Compassionateuseofbevacizumab（Avastin）inchildrenandyoungadultswith

refractoryorrecurrentsolidtumors.

_Bevacizumab-inducedtransientremodelingofthevasculatureinneuroblastoma

xenograftsresultsinimproveddeliveryandefficacyofsystemicallyadministered

chemotherapy.

_ProteomicsApproachestotheSystemsBiologyofCardiovascularDiseases

_Pre-andpost-nataltreatmentofhemophagocyticlymphohistiocytosis.

_Lackofearlybevacizumab-relatedskeletalradiographicchangesinchildrenwith

neuroblastoma.

_Interleukin-4activatesandrogenreceptorthroughCBP/p300

_Trisomy8inanallogeneicstemcelltransplantrecipientrepresentativeofa

donor-derivedconstitutionalabnormality.

_DisruptionofdiacylglycerolmetabolismimpairstheinductionofTcellanergy

_TcellanergyisreversedbyactiveRasandisregulatedbydiacylglycerolkinase-

_High-doseconformalRTimprovestumorcontrolinpatientswithprostatecancer

_VitaminDconcentrationdoesnotaffecttheriskofprostatecancer

_Liverresectionwithsalvagetransplantationforhepatocellularcarcinoma

_Theimpactofhistopathologicdiagnosisonthepropermanagementoftestisneoplasms

_Prostatestemcellantigenisassociatedwithdiffuse-typegastriccancer

_Multiplemyeloma:

high-riskimmunophenotypesidentified

_Increasedc-kitexpressionpredictspooroutcomeinacutemyeloidleukemia

_GlobalAnalysisoftheMeioticCrossoverLandscape

_SerumResponseFactorIsRequiredforSproutingAngiogenesisandVascularIntegrity

_IntegrinTraffickingRegulatedbyRab21IsNecessaryforCytokinesis

_ReducedTranslocationofNascentPrionProteinDuringERStressContributesto

Neurodegeneration

_Effectsoforalniacinonendothelialdysfunctioninpatientswithcoronaryarterydisease:

Resultsoftherandomized,double-blind,placebo-controlledINEFstudy.

_Globalexperienceswithvardenafilinmenwitherectiledysfunctionandunderlying

conditions.

_Noninvasivecardiacimaging:

implicationsforriskassessmentinadolescentsandyoung

adults.

_Transforminggrowthfactorbeta1T29Cgenepolymorphismandhypertension:

Relationshipwithcardiovascularandrenaldamage.

_Acomparisonofhormonetherapiesontheurinaryexcretionofprostacyclinand

thromboxaneA2.

_Repairofaninfectedaorticaneurysmusinganaorticallograftandavenousautograft:

Reportofacase.

_CirculatingLeptinandStress-inducedCardiovascularActivityinHumans.

_Effectsofaspirindoseonischaemiceventsandbleedingafterpercutaneouscoronary

intervention:

insightsfromthePCI-CUREstudy.

_Long-termcardiovascularoutcomesfollowingischemicheartdiseaseinpatientswithand

withoutperipheralvasculardisease.

_Reducedrenalfunctionandsleep-disorderedbreathingincommunity-dwellingelderly

men.

_Intracoronarypharmacotherapyinthemanagementofcoronarymicrovascular

dysfunction.

_Inhibitionofplateletaggregationbycombinedtherapywithaspirinandcilostazolafter

off-pumpcoronaryarterybypasssurgery.

_InhibitionofCCR2AmelioratesInsulinResistanceandHepaticSteatosisindb/dbMice

Abstract要求简洁，连贯

_Theacquisitionofmetastaticabilitybytumorcellsisconsideredalateeventinthe

evolutionofmalignanttumors.Wereportthatuntransformedmousemammarycellsthat

havebeenengineeredtoexpresstheinducibleoncogenictransgenesMYCandKrasD12,or

polyomamiddleT,andintroducedintothesystemiccirculationofamousecanbypass

transformationattheprimarysiteanddevelopintometastaticpulmonarylesionsupon

immediateordelayedoncogeneinduction.Therefore,previouslyuntransformed

mammarycellsmayestablishresidenceinthelungoncetheyhaveenteredthe

bloodstreamandmayassumemalignantgrowthupononcogeneactivation.Mammary

cellslackingoncogenictransgenesdisplayedasimilarcapacityforlong-termresidencein

thelungsbutdidnotformectopictumors.

_AlmosttwodecadesafterCFTRwasidentifiedasthegeneresponsibleforcysticfibrosis

（CF）,westilllackanswerstomanyquestionsaboutthepathogenesisofthedisease,andit

remainsincurable.MicewithadisruptedCFTRgenehavegreatlyfacilitatedCFstudies,

butthemutantmicedonotdevelopthecharacteristicmanifestationsofhumanCF,

includingabnormalitiesofthepancreas,lung,intestine,liver,andotherorgans.Because

pigssharemanyanatomicalandphysiologicalfeatureswithhumans,wegeneratedpigs

withatargeteddisruptionofbothCFTRalleles.NewbornpigslackingCFTRexhibited

defectivechloridetransportanddevelopedmeconiumileus,exocrinepancreatic

destruction,andfocalbiliarycirrhosis,replicatingabnormalitiesseeninnewbornhumans

withCF.Thepigmodelmayprovideopportunitiestoaddresspersistentquestionsabout

CFpathogenesisandacceleratediscoveryofstrategiesforpreventionandtreatment.

_Variablelymphocytereceptors（VLRs）ratherthanantibodiesplaytheprimaryrolein

recognitionofantigensintheadaptiveimmunesystemofjawlessvertebrates.

Combinatorialassemblyofleucine-richrepeat（LRR）genesegmentsachievesthe

requiredrepertoireforantigenrecognition.Wehavedeterminedacrystalstructurefora

VLR-antigencomplex,VLRRBC36incomplexwiththeH-antigentrisaccharidefrom

humanbloodtypeOerythrocytes,at1.67angstromresolution.RBC36bindsthe

H-trisaccharideontheconcavesurfaceoftheLRRmodulesofthesolenoidstructure

wherethreekeyhydrophilicresidues,multiplevanderWaalsinteractions,andthehighly

variableinsertofthecarboxyl-terminalLRRmoduledetermineantigenrecognitionand

specificity.Theconcavesurfaceassembledfromthemosthighlyvariableregionsofthe

LRRs,alongwithdiversityinthesequenceandlengthofthehighlyvariableinsert,can

accountfortherecognitionofdiverseantigensbyVLRs.

_A51-year-oldmanwithadiagnosisofmyelodysplasiaandnon-Hodgkin'slymphoma

underwentanunmatchedallogenicbonemarrowtransplantationandwastreated

posttransplantwithchronicimmunosuppressivemedication.Eightmonthsfollowing

transplantation,hepresentedwithprogressivedysarthria,cognitiveandvisualdecline.

Evaluationincludedbrainmagneticresonance（MR）imagingdemonstratingmultifocal

areasofincreasedT2andFLAIR（fluidattenuatedinversionrecovery）signalsinvolving

theleftfrontal,parietal,andoccipitallobes.TheMRlesionsdemonstrateddiffuse

increasedsignalonDWI（diffusion-weightedimages）andnormaltolowsignalonADC

（apparentdiffusioncoefficients）.Contrast-enhancedT1imageswereunremarkable.

Lumbarpuncturerevealedamildelevationincerebrospinalfluid（CSF）protein.CSF

PCRassayforviralDNAfragmentswerenegativeontwooccasions.Serumserologyfor

HIVwasnegativeaswell.Abrainbiopsywassubsequentlyperformed.Theclinicaland

neuroimagingdifferentialdiagnosesaswellasneuropathologiccorrelationarepresented.

_Invitro-generatedmesenchymalstemcells（MSCs）initiallyattractedinterestfortheir

abilitytoundergodifferentiationtowardcellsofdifferentlineages.

_Theseresultssuggestedthat

_However,therearestillobstaclesin

_Themajorchallengeforsuccessfuldrugdevelopmentisidentifyingdeliverystrategies

thatcanbetranslatedtotheclinic.

_ThisreviewwilldiscussprogressindevelopingandtestingsmallRNAi-baseddrugsand

potentialobstacles.

_Thisreviewhighlightswhat

_Inaddition,thereareindicationsthat

_Properconsiderationofalloftheseissueswillbenecessaryin

_Thesestudiesprovide

_Thispaperpresentsthepotentialapplicationsandthehurdlesfacinganti-HCVsiRNA

drugs.

_ThepresentreviewprovidesinsightintothefeasibletherapeuticstrategiesofsiRNA

technology,anditspotentialforsilencinggenesassociatedwithHCVdisease.

_Abasicprobleminthedesignofxxispresentedbythechoiceofaxxrateforthe

measurementofexperimentalvariables.

_Thispaperexaminesanewmeasureofxxinxxbasedonfuzzymathematicswhich

overcomesthedifficultiesfoundinotherxxmeasures.

_Thispaperdescribesasystemfortheanalysisofthexx.

_Themethodinvolvestheconstructionofxxfromfuzzyrelations.

_Theprocedureisusefulinanalyzinghowgroupsreachadecision.

_Thetechniqueusedistoemployanewlydevelopedandversatilexxalgorithms.

_Theusefulnessofxxisalsoconsidered.

_Abriefmethodologyusedinxxisdiscussed.

_Theanalysisisusefulinxxandxxproblem.

_Amodelisdevelopedforaxxanalysisusingfuzzymatrices.

_Algorithmstocombinetheseestimatesandproduceaxxarepresentedandjustified.

_Theuseofthemethodisdiscussedandanexampleisgiven.

_Resultsofanexperimentalapplicationsofthisxxanalysisprocedurearegivento

illustratetheproposedtechnique.

_Thispaperanalysesproblemsin

_Thispaperoutlinesthefunctionscarriedoutby...

_Thispaperincludesanillustrationofthe...

_Thispaperprovidesanoverviewandinformationusefulforapproaching

_Emphasisisplacedontheconstructionofacriterionfunctionbywhichthexxin

achievingahierarchicalsystemofobjectivesareevaluated.

_Themainemphasisisplacedontheproblemofxx

_Ourproposedmodelisverifiedthroughexperimentalstudy.

_Theexperimentalresultsrevealinterestingexamplesoffuzzyphasesof:

xx,xx

_Thecompatibilityofaprojectintermsofcost,andxxarelikewiserepresentedby

linguisticvariables.

_Adidacticexampleisincludedtoillustratethecomputationalprocedure

Introduction引证核心文献，提出假设，指出文章的核心观点

Beginning

_Overthecourseofthepast30years,..hasemergedformintuitive

_Weevaluated508participantswho

_Acutekidne