1、共享医学SCI论文经典句子汇总医学生物学SCI论文经典句子汇编Title要求简练,精确_ Compassionate use of bevacizumab (Avastin) in children and young adults withrefractory or recurrent solid tumors._ Bevacizumab-induced transient remodeling of the vasculature in neuroblastomaxenografts results in improved delivery and efficacy of systemic
2、ally administeredchemotherapy._ Proteomics Approaches to the Systems Biology of Cardiovascular Diseases_ Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis._ Lack of early bevacizumab-related skeletal radiographic changes in children withneuroblastoma._ Interleukin-4 activates andro
3、gen receptor through CBP/p300_ Trisomy 8 in an allogeneic stem cell transplant recipient representative of adonor-derived constitutional abnormality._ Disruption of diacylglycerol metabolism impairs the induction of T cell anergy_ T cell anergy is reversed by active Ras and is regulated by diacylgly
4、cerol kinase-_ High-dose conformal RT improves tumor control in patients with prostate cancer_ Vitamin D concentration does not affect the risk of prostate cancer_ Liver resection with salvage transplantation for hepatocellular carcinoma_ The impact of histopathologic diagnosis on the proper managem
5、ent of testis neoplasms_ Prostate stem cell antigen is associated with diffuse-type gastric cancer_ Multiple myeloma: high-risk immunophenotypes identified_ Increased c-kit expression predicts poor outcome in acute myeloid leukemia_ Global Analysis of the Meiotic Crossover Landscape_ Serum Response
6、Factor Is Required for Sprouting Angiogenesis and Vascular Integrity_ Integrin Trafficking Regulated by Rab21 Is Necessary for Cytokinesis_ Reduced Translocation of Nascent Prion Protein During ER Stress Contributes toNeurodegeneration_ Effects of oral niacin on endothelial dysfunction in patients w
7、ith coronary artery disease:Results of the randomized, double-blind, placebo-controlled INEF study._ Global experiences with vardenafil in men with erectile dysfunction and underlyingconditions._ Noninvasive cardiac imaging: implications for risk assessment in adolescents and youngadults._ Transform
8、ing growth factor beta1 T29C gene polymorphism and hypertension:Relationship with cardiovascular and renal damage._ A comparison of hormone therapies on the urinary excretion of prostacyclin andthromboxane A2._ Repair of an infected aortic aneurysm using an aortic allograft and a venous autograft:Re
9、port of a case._ Circulating Leptin and Stress-induced Cardiovascular Activity in Humans._ Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronaryintervention: insights from the PCI-CURE study._ Long-term cardiovascular outcomes following ischemic heart disease in patien
10、ts with andwithout peripheral vascular disease._ Reduced renal function and sleep-disordered breathing in community-dwelling elderlymen._ Intracoronary pharmacotherapy in the management of coronary microvasculardysfunction._ Inhibition of platelet aggregation by combined therapy with aspirin and cil
11、ostazol afteroff-pump coronary artery bypass surgery._ Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db MiceAbstract 要求简洁,连贯_ The acquisition of metastatic ability by tumor cells is considered a late event in theevolution of malignant tumors. We report that untransfor
12、med mouse mammary cells thathave been engineered to express the inducible oncogenic transgenes MYC and KrasD12, orpolyoma middle T, and introduced into the systemic circulation of a mouse can bypasstransformation at the primary site and develop into metastatic pulmonary lesions uponimmediate or dela
13、yed oncogene induction. Therefore, previously untransformedmammary cells may establish residence in the lung once they have entered thebloodstream and may assume malignant growth upon oncogene activation. Mammarycells lacking oncogenic transgenes displayed a similar capacity for long-term residence
14、inthe lungs but did not form ectopic tumors._ Almost two decades after CFTR was identified as the gene responsible for cystic fibrosis(CF), we still lack answers to many questions about the pathogenesis of the disease, and itremains incurable. Mice with a disrupted CFTR gene have greatly facilitated
15、 CF studies,but the mutant mice do not develop the characteristic manifestations of human CF,including abnormalities of the pancreas, lung, intestine, liver, and other organs. Becausepigs share many anatomical and physiological features with humans, we generated pigswith a targeted disruption of bot
16、h CFTR alleles. Newborn pigs lacking CFTR exhibiteddefective chloride transport and developed meconium ileus, exocrine pancreaticdestruction, and focal biliary cirrhosis, replicating abnormalities seen in newborn humanswith CF. The pig model may provide opportunities to address persistent questions
17、aboutCF pathogenesis and accelerate discovery of strategies for prevention and treatment._ Variable lymphocyte receptors (VLRs) rather than antibodies play the primary role inrecognition of antigens in the adaptive immune system of jawless vertebrates.Combinatorial assembly of leucine-rich repeat (L
18、RR) gene segments achieves therequired repertoire for antigen recognition. We have determined a crystal structure for aVLR-antigen complex, VLR RBC36 in complex with the H-antigen trisaccharide fromhuman blood type O erythrocytes, at 1.67 angstrom resolution. RBC36 binds theH-trisaccharide on the co
19、ncave surface of the LRR modules of the solenoid structurewhere three key hydrophilic residues, multiple van der Waals interactions, and the highlyvariable insert of the carboxyl-terminal LRR module determine antigen recognition andspecificity. The concave surface assembled from the most highly vari
20、able regions of theLRRs, along with diversity in the sequence and length of the highly variable insert, canaccount for the recognition of diverse antigens by VLRs._ A 51-year-old man with a diagnosis of myelodysplasia and non-Hodgkins lymphomaunderwent an unmatched allogenic bone marrow transplantat
21、ion and was treatedposttransplant with chronic immunosuppressive medication. Eight months followingtransplantation, he presented with progressive dysarthria, cognitive and visual decline.Evaluation included brain magnetic resonance (MR) imaging demonstrating multifocalareas of increased T2 and FLAIR
22、 (fluid attenuated inversion recovery) signals involvingthe left frontal, parietal, and occipital lobes. The MR lesions demonstrated diffuseincreased signal on DWI (diffusion-weighted images) and normal to low signal on ADC(apparent diffusion coefficients). Contrast-enhanced T1 images were unremarka
23、ble.Lumbar puncture revealed a mild elevation in cerebrospinal fluid (CSF) protein. CSFPCR assay for viral DNA fragments were negative on two occasions. Serum serology forHIV was negative as well. A brain biopsy was subsequently performed. The clinical andneuroimaging differential diagnoses as well
24、as neuropathologic correlation are presented._ In vitro-generated mesenchymal stem cells (MSCs) initially attracted interest for theirability to undergo differentiation toward cells of different lineages._ These results suggested that_ However, there are still obstacles in_ The major challenge for s
25、uccessful drug development is identifying delivery strategiesthat can be translated to the clinic._ This review will discuss progress in developing and testing small RNAi-based drugs andpotential obstacles._ This review highlights what_ In addition, there are indications that_ Proper consideration o
26、f all of these issues will be necessary in_ These studies provide_ This paper presents the potential applications and the hurdles facing anti-HCV siRNAdrugs._ The present review provides insight into the feasible therapeutic strategies of siRNAtechnology, and its potential for silencing genes associ
27、ated with HCV disease._ A basic problem in the design of xx is presented by the choice of a xx rate for themeasurement of experimental variables._ This paper examines a new measure of xx in xx based on fuzzy mathematics whichovercomes the difficulties found in other xx measures._ This paper describe
28、s a system for the analysis of the xx._ The method involves the construction of xx from fuzzy relations._ The procedure is useful in analyzing how groups reach a decision._ The technique used is to employ a newly developed and versatile xx algorithms._ The usefulness of xx is also considered._ A bri
29、ef methodology used in xx is discussed._ The analysis is useful in xx and xx problem._ A model is developed for a xx analysis using fuzzy matrices._ Algorithms to combine these estimates and produce a xx are presented and justified._ The use of the method is discussed and an example is given._ Resul
30、ts of an experimental applications of this xx analysis procedure are given toillustrate the proposed technique._ This paper analyses problems in_ This paper outlines the functions carried out by ._ This paper includes an illustration of the ._ This paper provides an overview and information useful f
31、or approaching_ Emphasis is placed on the construction of a criterion function by which the xx inachieving a hierarchical system of objectives are evaluated._ The main emphasis is placed on the problem of xx_ Our proposed model is verified through experimental study._ The experimental results reveal
32、 interesting examples of fuzzy phases of : xx,xx_ The compatibility of a project in terms of cost, and xx are likewise represented bylinguistic variables._ A didactic example is included to illustrate the computational procedureIntroduction 引证核心文献,提出假设,指出文章的核心观点Beginning_ Over the course of the past 30 years, . has emerged form intuitive_ We evaluated 508 participants who_ Acute kidne
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