Andrews' Diseases of the Skin _ Clinical Dermatology (2015, Elsevier).pdf

Andrews' Diseases of the Skin _ Clinical Dermatology (2015, Elsevier).pdf

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tahir99-UnitedVRGUseofthecurrenteditionoftheelectronicversionofthisbook（eBook）issubjecttothetermsofthenontransferable,limitedlicensegrantedon.AccesstotheeBookislimitedtothefirstindividualwhoredeemsthePIN,locatedontheinsidecoverofthisbook,atandmaynotbetransferredtoanotherpartybyresale,lendingorothermeans.Anyscreen.Anytime.Anywhere.ActivatetheeBookversionofthistitleatnoadditionalcharge.UnlockyoureBooktoday.1VisitScratchoffyourcode3Typecodeinto“EnterCode”box4Click“Redeem”5LoginorSignUp6Goto“MyLibrary”Itsthateasy!

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e.tahir99-UnitedVRGVIDEOCONTENTSVideosavailableat37-1Shavebiopsy37-2Punchbiopsy37-3Narrowholelipomaexcision37-4Excision37-5Fusiformexcision37-6Transpositionflap37-7Splitthicknessskingraft37-8Mohssurgery38-1Fullfaceablativeresurfacing39-1Filler,lips39-2Botulinumtoxin,glabella39-3Botulinumtoxin,frontalis39-4Starchiodinetestforhyperhidrosis39-5Botulinumtoxin,hyperhidrosisaxilla39-6Sclerotherapy39-7FoamsclerotherapyThispageintentionallyleftblanktahir99-UnitedVRGAndrewsDiseasesoftheSkinCLINICALDERMATOLOGYExecutiveContentStrategist:

RussellGabbedySeniorContentDevelopmentSpecialist:

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Dr.WilliamD.James.tahir99-UnitedVRGAndrewsDiseasesoftheSkinCLINICALDERMATOLOGYTwelfthEditionWilliamD.James,MDPaulRGrossProfessorofDermatologyDepartmentofDermatologyUniversityofPennsylvaniaSchoolofMedicinePhiladelphia,PennsylvaniaTimothyG.Berger,MDProfessorofClinicalDermatologyExecutiveViceChairandResidencyProgramDirectorChairinDermatologyMedicalStudentEducationUniversityofCalifornia,SanFranciscoSanFrancisco,CaliforniaDirkM.Elston,MDProfessorandChairmanDepartmentofDermatologyandDermatologicSurgeryMedicalUniversityofSouthCarolinaCharleston,SouthCarolina;FormerDirectorAckermanAcademyofDermatopathologyNewYork,NewYorktahir99（blink99）UnitedVRG,OriginalRelease.https:

/kat.cr/user/Blink99/1600JohnF.KennedyBlvd.Ste.1800Philadelphia,PA19103-2899ANDREWSDISEASESOFTHESKIN:

CLINICALDERMATOLOGY,TWELFTHEDITIONISBN:

978-0-323-31967-6InternationalEditionISBN:

978-0-323-31968-3Copyright2016byElsevier,Inc.Allrightsreserved.11thedition2011byElsevier,Inc.Nopartofthispublicationmaybereproducedortransmittedinanyformorbyanymeans,electronicormechanical,includingphotocopying,recording,oranyinformationstorageandretrievalsystem,withoutpermissioninwritingfromthepublisher.Detailsonhowtoseekpermission,furtherinformationaboutthePublisherspermissionspoliciesandourarrangementswithorganizationssuchastheCopyrightClearanceCenterandtheCopyrightLicensingAgency,canbefoundatourwebsite:

bookandtheindividualcontributionscontainedinitareprotectedundercopyrightbythePublisher（otherthanasmaybenotedherein）.NoticesKnowledgeandbestpracticeinthisfieldareconstantlychanging.Asnewresearchandexperiencebroadenourunderstanding,changesinresearchmethods,professionalpractices,ormedicaltreatmentmaybecomenecessary.Practitionersandresearchersmustalwaysrelyontheirownexperienceandknowledgeinevaluatingandusinganyinformation,methods,compounds,orexperimentsdescribedherein.Inusingsuchinformationormethodstheyshouldbemindfuloftheirownsafetyandthesafetyofothers,includingpartiesforwhomtheyhaveaprofessionalresponsibility.Withrespecttoanydrugorpharmaceuticalproductsidentified,readersareadvisedtocheckthemostcurrentinformationprovided（i）onproceduresfeaturedor（ii）bythemanufacturerofeachproducttobeadministered,toverifytherecommendeddoseorformula,themethodanddurationofadministration,andcontraindications.Itistheresponsibilityofpractitioners,relyingontheirownexperienceandknowledgeoftheirpatients,tomakediagnoses,todeterminedosagesandthebesttreatmentforeachindividualpatient,andtotakeallappropriatesafetyprecautions.Tothefullestextentofthelaw,neitherthePublishernortheauthors,contributors,oreditors,assumeanyliabilityforanyinjuryand/ordamagetopersonsorpropertyasamatterofproductsliability,negligenceorotherwise,orfromanyuseoroperationofanymethods,products,instructions,orideascontainedinthematerialherein.InternationalStandardBookNumber:

ISBN:

978-0-323-31967-6PrintedinChinaLastdigitistheprintnumber:

987654321tahir99-UnitedVRGvCONTENTS1Skin:

BasicStructureandFunction12CutaneousSignsandDiagnosis113DermatosesResultingfromPhysicalFactors184PruritusandNeurocutaneousDermatoses455AtopicDermatitis,Eczema,andNoninfectiousImmunodeficiencyDisorders626ContactDermatitisandDrugEruptions907ErythemaandUrticaria1368ConnectiveTissueDiseases1539Mucinoses17910SeborrheicDermatitis,Psoriasis,RecalcitrantPalmoplantarEruptions,PustularDermatitis,andErythroderma18511PityriasisRosea,PityriasisRubraPilaris,andOtherPapulosquamousandHyperkeratoticDiseases19912LichenPlanusandRelatedConditions20913Acne22514BacterialInfections24515DiseasesResultingfromFungiandYeasts28516MycobacterialDiseases31917HansensDisease33118Syphilis,Yaws,Bejel,andPinta34319ViralDiseases35920ParasiticInfestations,Stings,andBites41821ChronicBlisteringDermatoses45122NutritionalDiseases47123DiseasesofSubcutaneousFat48024EndocrineDiseases49125AbnormalitiesofDermalFibrousandElasticTissue50026ErrorsinMetabolism50927GenodermatosesandCongenitalAnomalies54228DermalandSubcutaneousTumors57929EpidermalNevi,Neoplasms,andCysts62530MelanocyticNeviandNeoplasms68031Macrophage/MonocyteDisorders69932CutaneousLymphoidHyperplasia,CutaneousT-CellLymphoma,OtherMalignantLymphomas,andAlliedDiseases72633DiseasesoftheSkinAppendages74734DisordersoftheMucousMembranes78935CutaneousVascularDiseases80736DisturbancesofPigmentation85637DermatologicSurgery87438CutaneousLaserSurgery90139CosmeticDermatology913ThispageintentionallyleftblankviiPREFACEANDACKNOWLEDGMENTSAndrewsremainsasitwasfromthebeginning:

anauthoredtextwhoseonevolumeisfilledwithclinicalsigns,symptoms,diagnostictests,andtherapeuticpearls.Theauthorshaveremainedgeneralclinicaldermatologistsinaneraofsubspe-cialistsinacademia.TheyarecommittedtokeepingAndrewsasanexcellenttoolforanyonewhoneedshelpindiagnosingapatientwithaclinicalconundrumortreatingapatientwithatherapeuticallychallengingdisease.Andrewsisprimarilyintendedforthepracticingdermatolo-gist.Itismeanttobeusedonthedesktopathisorherclinic,givingconsistent,conciseadviceonthewholespectrumofclinicalsituationsfacedinthecourseofabusyworkday.Whilewehavebeentruetoourcommitmenttoasingle-volumework,weprovideourtextinaconvenientonlineformataswell.Becauseofitsrelativebrevitybutcompletecoverageofourfield,manyfindthetextidealforlearningdermatologyforthefirsttime.Ithasbeenamainstayoftheresidentyearlycurriculumformanyprograms.Wearehopefulthattraineeswilllearnclinicaldermatologybystudyingtheclinicaldescrip-tions,diseaseclassifications,andtreatmentinsightsthatdefineAndrews.Webelievethatstudents,interns,internistsorothermedicalspecialists,familypractitioners,andotherhealthpro-fessionalswhodesireacomprehensivedermatologytextbookwillfindthatoursmeetstheirneeds.Long-timedermatolo-gistswillhopefullydiscoverAndrewstobetheneededupdatethatsatisfiestheirlifelonglearningdesires.Onourcollectivetripsaroundtheworld,wehavebeengratifiedtoseeourinternationalcolleaguesstudyingAndrews.ThousandsofbookshavebeenpurchasedbyChineseandBrazilianderma-tologistsalone.Manymajorchangeshavebeenmadetothisedition.BillJames,TimBerger,andDirkElston,threegreatfriendsofoverthreedecades,haveworkedcloselytocontinuetoimprovethequalityofourtext.ThesurgicalchaptershavebeenupdatedandexpandedbyIsaacNeuhaus.Hehasaddedvideosofsomeofthemostcommonprocedures,whichareavailableonline.Wethankhimforhiscontinuedworktoimprovethisportionofourtextbook.RobertMichelettiexpertlyupdatedChapters29and35.Heisaninternist/dermatologistwithsuperiorwritingskillswhosecontributionsaremostappreciated.Wehavetriedtoensurethateachentityisdiscussedonlyonce,inacompleteyetconcisemanner.Inordertodothiswehavehadtomakedecisionsregardingtheplacementofdiseaseprocessesinonlyonesite.Clearly,neutrophiliceccrinehidrad-enitis,forexample,couldbepresentedunderdrugeruptions,neutrophilicreactiveconditions,infectionorcancer-associateddisease,orwitheccrinedisorders.Thefinaldecisionsareateameffortandmadeintheinterestofeliminatingredun-dancy.Thisallowsustopresentourunifiedphilosophyintreatingpatientsinonedensevolume.Medicalsciencecontinuestoprogressatbreakneckspeed.Ourunderstandingoftheetiologyofcertainconditionshasnowledustorecategorizewell-recognizeddiseasestatesanddictatedtheadditionofmanynewlydescribedentities.Molec-ularinvestigativetechniques,technologicbreakthroughs,anddesignertherapeuticsleadthewayinprovidingadvancesinourspecialty.Wecoverthenewunderstandingfoll