Andrews' Diseases of the Skin _ Clinical Dermatology (2015, Elsevier).pdf

1、tahir99-UnitedVRGUse of the current edition of the electronic version of this book(eBook)is subject to the terms of the nontransferable,limited license granted on .Access to the eBook is limited to the first individual who redeems the PIN,located on the inside cover of this book,at and may not be tr

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4、le device:e.tahir99-UnitedVRGVIDEO CONTENTSVideos available at 37-1 Shavebiopsy37-2 Punchbiopsy37-3 Narrowholelipomaexcision37-4 Excision37-5 Fusiformexcision37-6 Transpositionflap37-7 Splitthicknessskingraft37-8 Mohssurgery38-1 Fullfaceablativeresurfacing39-1 Filler,lips39-2 Botulinumtoxin,glabella

5、39-3 Botulinumtoxin,frontalis39-4 Starchiodinetestforhyperhidrosis39-5 Botulinumtoxin,hyperhidrosisaxilla39-6 Sclerotherapy39-7 FoamsclerotherapyThis page intentionally left blanktahir99-UnitedVRGAndrews Diseases of the SkinCLINICAL DERMATOLOGYExecutive Content Strategist:Russell GabbedySenior Conte

6、nt Development Specialist:Ailsa LaingPublishing Services Manager:Patricia TannianSenior Project Manager:John CaseyDesigner:Christian BilbowOriginal cover images:Upper left:Dr.Donald Adler(deceased);Upper right:Dr.Shyam Verma;Center:Dr.Debabrata Bandyopadhyay;Lower right:Dr.William D.James.tahir99-Un

7、itedVRGAndrewsDiseasesof the SkinCLINICAL DERMATOLOGYTwelfth EditionWilliam D.James,MDPaul R Gross Professor of DermatologyDepartment of DermatologyUniversity of Pennsylvania School of MedicinePhiladelphia,PennsylvaniaTimothy G.Berger,MDProfessor of Clinical DermatologyExecutive Vice Chair and Resid

8、ency Program DirectorChair in Dermatology Medical Student EducationUniversity of California,San FranciscoSan Francisco,CaliforniaDirk M.Elston,MDProfessor and ChairmanDepartment of Dermatology and Dermatologic SurgeryMedical University of South CarolinaCharleston,South Carolina;Former DirectorAckerm

9、an Academy of DermatopathologyNew York,New Yorktahir99(blink99)UnitedVRG,Original Release.https:/kat.cr/user/Blink99/1600 John F.Kennedy Blvd.Ste.1800Philadelphia,PA 19103-2899ANDREWS DISEASES OF THE SKIN:CLINICAL DERMATOLOGY,TWELFTH EDITION ISBN:978-0-323-31967-6International Edition ISBN:978-0-323

10、-31968-3Copyright 2016 by Elsevier,Inc.All rights reserved.11th edition 2011 by Elsevier,Inc.No part of this publication may be reproduced or transmitted in any form or by any means,electronic or mechanical,including photocopying,recording,or any information storage and retrieval system,without perm

11、ission in writing from the publisher.Details on how to seek permission,further information about the Publishers permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency,can be found at our website: book and the individual

12、contributions contained in it are protected under copyright by the Publisher(other than as may be noted herein).NoticesKnowledge and best practice in this field are constantly changing.As new research and experience broaden our understanding,changes in research methods,professional practices,or medi

13、cal treatment may become necessary.Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information,methods,compounds,or experiments described herein.In using such information or methods they should be mindful of their own safety and the sa

14、fety of others,including parties for whom they have a professional responsibility.With respect to any drug or pharmaceutical products identified,readers are advised to check the most current information provided(i)on procedures featured or(ii)by the manufacturer of each product to be administered,to

15、 verify the recommended dose or formula,the method and duration of administration,and contraindications.It is the responsibility of practitioners,relying on their own experience and knowledge of their patients,to make diagnoses,to determine dosages and the best treatment for each individual patient,

16、and to take all appropriate safety precautions.To the fullest extent of the law,neither the Publisher nor the authors,contributors,or editors,assume any liability for any injury and/or damage to persons or property as a matter of products liability,negligence or otherwise,or from any use or operatio

17、n of any methods,products,instructions,or ideas contained in the material herein.International Standard Book Number:ISBN:978-0-323-31967-6Printed in ChinaLast digit is the print number:9 8 7 6 5 4 3 2 1tahir99-UnitedVRGvCONTENTS1 Skin:Basic Structure and Function 12 Cutaneous Signs and Diagnosis 113

18、 Dermatoses Resulting from Physical Factors 184 Pruritus and Neurocutaneous Dermatoses 455 Atopic Dermatitis,Eczema,and Noninfectious Immunodeficiency Disorders 626 Contact Dermatitis and Drug Eruptions 907 Erythema and Urticaria 1368 Connective Tissue Diseases 1539 Mucinoses 17910 Seborrheic Dermat

19、itis,Psoriasis,Recalcitrant Palmoplantar Eruptions,Pustular Dermatitis,and Erythroderma 18511 Pityriasis Rosea,Pityriasis Rubra Pilaris,and Other Papulosquamous and Hyperkeratotic Diseases 19912 Lichen Planus and Related Conditions 20913 Acne 22514 Bacterial Infections 24515 Diseases Resulting from

20、Fungi and Yeasts 28516 Mycobacterial Diseases 31917 Hansens Disease 33118 Syphilis,Yaws,Bejel,and Pinta 34319 Viral Diseases 35920 Parasitic Infestations,Stings,and Bites 41821 Chronic Blistering Dermatoses 45122 Nutritional Diseases 47123 Diseases of Subcutaneous Fat 48024 Endocrine Diseases 49125

21、Abnormalities of Dermal Fibrous and Elastic Tissue 50026 Errors in Metabolism 50927 Genodermatoses and Congenital Anomalies 54228 Dermal and Subcutaneous Tumors 57929 Epidermal Nevi,Neoplasms,and Cysts 62530 Melanocytic Nevi and Neoplasms 68031 Macrophage/Monocyte Disorders 69932 Cutaneous Lymphoid

22、Hyperplasia,Cutaneous T-Cell Lymphoma,Other Malignant Lymphomas,and Allied Diseases 72633 Diseases of the Skin Appendages 74734 Disorders of the Mucous Membranes 78935 Cutaneous Vascular Diseases 80736 Disturbances of Pigmentation 85637 Dermatologic Surgery 87438 Cutaneous Laser Surgery 90139 Cosmet

23、ic Dermatology 913This page intentionally left blankviiPREFACE AND ACKNOWLEDGMENTSAndrews remains as it was from the beginning:an authored text whose one volume is filled with clinical signs,symptoms,diagnostic tests,and therapeutic pearls.The authors have remained general clinical dermatologists in

24、 an era of subspe-cialists in academia.They are committed to keeping Andrews as an excellent tool for anyone who needs help in diagnosing a patient with a clinical conundrum or treating a patient with a therapeutically challenging disease.Andrews is primarily intended for the practicing dermatolo-gi

25、st.It is meant to be used on the desktop at his or her clinic,giving consistent,concise advice on the whole spectrum of clinical situations faced in the course of a busy workday.While we have been true to our commitment to a single-volume work,we provide our text in a convenient online format as wel

26、l.Because of its relative brevity but complete coverage of our field,many find the text ideal for learning dermatology for the first time.It has been a mainstay of the resident yearly curriculum for many programs.We are hopeful that trainees will learn clinical dermatology by studying the clinical d

27、escrip-tions,disease classifications,and treatment insights that define Andrews.We believe that students,interns,internists or other medical specialists,family practitioners,and other health pro-fessionals who desire a comprehensive dermatology textbook will find that ours meets their needs.Long-tim

28、e dermatolo-gists will hopefully discover Andrews to be the needed update that satisfies their lifelong learning desires.On our collective trips around the world,we have been gratified to see our international colleagues studying Andrews.Thousands of books have been purchased by Chinese and Brazilia

29、n derma-tologists alone.Many major changes have been made to this edition.Bill James,Tim Berger,and Dirk Elston,three great friends of over three decades,have worked closely to continue to improve the quality of our text.The surgical chapters have been updated and expanded by Isaac Neuhaus.He has ad

30、ded videos of some of the most common procedures,which are available online.We thank him for his continued work to improve this portion of our textbook.Robert Micheletti expertly updated Chapters 29 and 35.He is an internist/dermatologist with superior writing skills whose contributions are most app

31、reciated.We have tried to ensure that each entity is discussed only once,in a complete yet concise manner.In order to do this we have had to make decisions regarding the placement of disease processes in only one site.Clearly,neutrophilic eccrine hidrad-enitis,for example,could be presented under dr

32、ug eruptions,neutrophilic reactive conditions,infection or cancer-associated disease,or with eccrine disorders.The final decisions are a team effort and made in the interest of eliminating redun-dancy.This allows us to present our unified philosophy in treating patients in one dense volume.Medical s

33、cience continues to progress at breakneck speed.Our understanding of the etiology of certain conditions has now led us to recategorize well-recognized disease states and dictated the addition of many newly described entities.Molec-ular investigative techniques,technologic breakthroughs,and designer therapeutics lead the way in providing advances in our specialty.We cover the new understanding foll