医学微生物英语教学大纲6版.docx

医学微生物英语教学大纲6版.docx

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医学微生物英语教学大纲6版

MedicalMicrobiology

Introduction

•Microbiologyisthebiologyofmicroorganismsthataresmall,simplestructureandnotdirectlyvisibletounaidedeye.Itisabioscienceforthestudyoftheevolution,classification,morphologyofmicrobesundercertaindefiniteconditions,thelawoftheirlifeactivities,andtheirinteractionwithhumanbeings,animalsorplantsaswellaswithnaturalenvironment.Microorganismsarecreaturesthatarenotdirectlyvisibletotheunaidedeye,withdramaticalbiologicdiversity.Viruses,bacteria,fungi,protozoaandsomealgaeareallinthiscategory.Themedicalmicrobiologyisoneoftheessentialbasicsciences.ItisthestudyofBiologicalcharacteristicsofmicroorganismsandtheirrelationshipswithhumanhosts

contents

1.Bologicalpropertiesofmicroorganism6h

2.Infection3h

3.Immunitytomicroorganisminfection2h

4.Heredityandvariation3h

5.Medicalmicroecology,Nosocomialinfection,Disinfectionandsterilization2h

6.Diagnosis,preventionandcureofaetiology1h

7.Pyogenicbacteria2h

8.Enterobacteriaceae,Vibrios3h

9.Anaerobes1.5h

10.Bacteriainfectionthroughrespiratory1.5h

11.BacteriainfectionthroughZoonoticbacteria2h

12.RespiratoryVirus2.5h

13.Enterovirusgroup2.5h

14.HepatitisViruses3h

15.FlavivirusVirus0.5h

16.HemorrhagicFeverViruses0.5h

17.HerpesVirus1.5h

18.Retrovirus1.5h

19.OtherViruses,Prion,1.5h

20.Fungi1.5h

21.Othermicroorganism2h

ChapterBiologicalpropertiesofmicroorganism

[Requirement]

Bacteria

1.Masterthecellwallstructureofbacteriaandtheirfunctions

2.Masterthespecialstructureofbacteriaandtheirfunctions

3.Masterthefollowingconcepts:

1.plasmid2.capsule3.spore

4.L-formbacterium5.lipopolysaccharide（LPS）

4.UnderstandtheMetabolismofbacteriaandtheirproducts

5.Understandthegrowthcurveofbacteria

6.Understandthecellmembrane,cytoplasm,nuclearmaterialofbacteria

Virus

1.Masterthechemicalcompositionandfunctionofviruses

2.Masterthemajorfeatureofthereplicationcycleofviruses

3.Masterthefollowingconcepts:

1.virion2.interference3.prion4.defectivevirus（缺陷病毒）5.abortiveinfection（顿挫感染）

4.UnderstandthecharacteristicsofViralGenetics.

5.Understandtheeffectsofphysicalandchemicalagentsonviruses.

Fungus

1.Masterthegenearalcharacteristicsoffungi.（真菌）

2.Understandthemorphologyandculturepropertiesoffungi

[Classhour:

6hour]

[Content]

Bacteria

1.detailedexplaintheconceptionofbacteria,structure,specialstructure,Grams’stainandchemicalcompositionofbacteria.

2.2.generalexplainbacterialnutrientmaterials,bacterialgrowthandreproductionangbacterialmetabolism.

Virus

3.detailedexplaintheconceptionofvirus,StructureandChemicalCompositionandclassificationofvirus.

4.intensivelyexplaintheViralReplicationcycle（复制周期）adsorption（吸附）,

penetration（穿入）,uncoating（脱壳）,biosynthesis（生物合成）,assemblyandrelease（装配和释放）.

3.intensivelyexplainUnnormalmultiplication.

4.generalexplaintheViralGeneticsMutations;EffectsofPhysicalandChemicalAgentsonViruses.

Fungus

1.generalexplaincharacteristicsmorphology（形态）,properties,Classificationoffung

ChapterInfection

[Requirement]

1.Masterthemechanismofbacterialvirulence

2.Mastertheresource,chemicalcompositionandpathogenicmechanismofexotoxinandendotoxin

3.Masterthethepathwaysofviralinfectionsandtheviruseswhichcanresultinverticalinfection.

4.Masterthepathogenesisofviralinfectionandtheoncogenicvirusassociatedwithhumantumors.

5.Masterthethecharacteristicsofimmunityagainstvirusinfection

6.MasterthetheantiviralactivityofIFN.

7.Masterthefollowingconcepts:

1.verticaltransmission2.latentinfection3.slowvirusinfection

4.Interferon（IFN）5.neutrilizingantibody6.CPE7.infection8.exotoxin9.endotoxin

8.UnderstandtheclassificationofIFNandtheproductionofIFN.

9.Understandtheresource,routeandtypeofbacterialinfection.

10.Understandthemorphologyandculturepropertiesoffungi

[Classhour:

3hours]

[Content]

1.intensivelyexplainpathogenesisofbacterialInfection.

2.detailedexplaintheresource,chemicalcomposition,pathogenicmechanism.

3.detailedexplainthethepathwaysofviralinfectionsandthetypeofviralinfection,Immunityagainstvirusinfection.

4.intensivelyexplainPathogenesisofViralInfection.

5.generalexplainEpidemiology,examinationmethods,preventionandtreatment,Pathogenicityandimmunitydiagnosisoffungi

ChapterHeredityandVariation

[Requirement]

1.Mastertheconcept,maincharacteristicofplasmidandimportantplasmidofassociatedmecial.

2.Masterthemainmodeofgenetransferandrecombination.

3.Masterthefollowingconcepts:

1.Plasmid2.phage3.transformation4.conjugation5.transduction6.lysogenicconversion

4.Understandtheprincipleofheredityandvariation

5.Understandthevariationphenomenonofbacteria.

6.Understandthemedicalsignificanceofmicrobicheredityandvariation

[Classhour:

3hours]

[Content]

1.generalexplaintheprincipleofheredityandvariation

2.detailedexplainthevariationphenomenonofbacteria.

3.detailedexplainthemodeofphage.

4.intensivelyexplainthevariationmechanismofbacteria.

5.explaintheheredityandvariationofvirus.

6.generalexplainthemedicalsignificanceofmicrobicheredityandvariation

ChapterMedicalmicroecology,Nosocomialinfection,Disinfectionandsterilization

[Requirement]

1.Mastertheconceptofnormalfloraandconditionedpathogen

2.Masterthepathogenicconditionandmaincharacteristicofconditionedpathogen.

3.Masterthefollowingconcepts:

1.normalflora2.conditionedpathogen3.opportunisticinfection4.disinfection5.sterilization6.asepsis7.antiseptictechnique

4.Understandtheconceptandresearchcontentsofmedicalmicroecology.

5.Understand.

6.Understandthephysicsmethodsandchemicalmethodsofdisinfectionandasepsis.

[Classhour:

3hours]

[Content]

1.detailedexplainconditionedpathogenandopportunisticinfection.

2.explaintheconceptthemianmicroorganism,riskfactorsandpreventionandtherapyofnosocomialinfection.

3.detailedexplaintheconceptsofdisinfection,sterilization,asepsisandantiseptictechnique

5.detailedexplainmoistheatsterilization.

6.explainchemicalmethodsofdisinfectionandasepsis.

ChapterDiagnosis,preventionandtreatmentofaetiology

[Requirement]

1．Masterannouncementsofspecimencollectionandlaboratorydiagnosis

2．Masterthemainprocessofdetectionofpathogen

3．Masterthecultureofvirus

4．Understandthesignificanceofserodignosis

5．Understandtheexaminationmethodsofviralinfection.

[Classhour:

1hours]

[Content]

1.explainbacteriologicaldiagnosisandserologicaldiagnosis

2.explainthediagnosisofvirus

3.explainthedignosisoffungus

ChapterPyogenicbacteria

[Requirement]

1.Masterthepathogenicmaterials,mechanismsofcoccusanditsdisease

2.Understandthecommonproperties,examinationmethods,preventionandtreatmentofcoccus

[Classhour:

3hours]

[Content]

1.intensivelyexplainthepathogenicityofStaphylococcusandStreptococcus

2.intensivelyexplainthepathogenicityofS.pneumoniaeandNeisseria

3.explainthecommonproperties,examinationmethodsofcoccus

ChapterEnterobacteriaceae,Vibrios

[Requirement]

1.MasterthecommonpropertiesofBacteriumentericum

2.MasterthepathogenicityofBacteriumentericum

3.MasterthebiologicalcharacteristicsandpathogenicityofV.choleraae

4.Understandtheexaminationmethods,preventionandtreatmentofBacteriumentericum

5.Understandtheexaminationmethods,preventionandtreatmentofV.choleraae

[Classhour:

3hours]

[Content]

1.intensivelyexplainthemainbiologicalcharacteristicsandpathogenicityofShigella

2.intensivelyexplainthemainbiologicalcharacteristicsandpathogenicityofSalmonella

3.detailedexplainlaboratoryexaminationofBacteriumentericum

4.detailedexplainWidaltestanditsresultdecision

5.detailedexplaintheeffectofcholeraenterotoxinatpathogenesis

ChapterAnaerobes

[Requirement]

1.MasterthebiologicalcharacteristicsandpathogenicityofC.tetani

2.MasterhowtouseantitoxandanatoxineatdiseasecausedC.tetani

3.UnderstandthebiologicalcharacteristicsofC.perfringens

4.Understandpathogenicmechanismandcharacteristicsofclostridialmyonecrosis

5.UnderstandthepathogenesisofC.botulinum

[Classhour:

1.5hours]

[Content]

1.intensivelyexplainthebiologicalcharacteristics,pathogenicity,preventionandtreatmentofC.tetani

2.intensivelyexplainbiologicalcharacteristics,pathogenicmechanismandcharacteristicsofclostridialmyonecrosis

3.detailedexplainpathogenesisofClostridum

4.explainthetheclassificationofanaerobicbacteria

5.explainthetheclassification,commonproperties,distributionofNon-spore-forminganaerobes

ChapterBacteriainfectionthroughrespiratory

[Requirement]

1.Masterthebiologicalcharacteristics,pathogenicityandimmunityofMycobacterium

2.Mastertheprinciple,method,resultjudgementandsignificanceoftuberculintest

3.Masterthebiologicalcharacteristics,pathogenicity,immunityandtreatmentofC.dipheriae

4.UnderstandthebiologicalpropertiesofL.pneumophila

[Classhour:

1.5hours]

[Content]

1.intensivelyexplainthebiologicalcharacteristics,pathogenicityandimmunityofMycobacterium

2.intensivelyexplaintheprinciple,method,resultjudgementandsignificanceoftuberculintest

3.detailedexplainthebiologicalcharacteristics,pathogenicity,immunityandtreatmen