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内科病例
Case1
Male,62year-old,camefromemergencyroom
Chiefcomplaint:
coughandsputumfor20years,breathlessnessonexertionfor5years,symptomaggravationforaweek.
Presenthistory:
thepatienthadcoughandsputumof20years’duration.Recent5yearshehadshortofbreathonexertionandhissymptomprogressivelyaggravated.Aweekago,hebegantohaveyellowsputumandseveredyspnea.Althoughheusedmanydrugsathome,hisshortofbreathcouldn’tbereleased.
Physicalexamination:
cysnosisonhiship,wheezingandmoistralescanbeheardontwolungs.
PulmonaryfunctiontestshowedFEV45%predictedandFEV/FVC55%afterinhalingbronchodilator.
Analysisofarterybloodgases:
pH7.43PaCO284mmHgHCO3-46mmol/L.
Examinationofperipheralblood:
WBC12.6×109/L,N87%,L13%.
Question1pleasemakethecompletediagnoses,includingcomplications.
2whatcausedacuteexacerbationofthediseaseforrecent1week?
Case2
Male,32yearsold.
Chiefcomplaint:
feverandfatigueforonemonth,dyspneaaftermovementforoneweek.
Physicalexamination:
T38.5℃,tracheatowardtheright,theplumpcontouroftheleftlowerchest,decreasedfremitusandbreathsoundaswellasdullnessbypercussionattheleftlowerchest,norubfeeling.
ChestX-rayandlungCT:
pleuraleffusion.
Question1whatkindsoflaboratoryexaminationshouldbedonefirst?
Question2whatshouldbecautiousaboutwhenthorcentesisisbeingdone?
Question3whatisthemostimportantinpleuraleffusioninestablishingthediagnosisofmalignantpleuraleffusion?
Case3
Apreviouslyhealthy46-year-oldfemalepresentedtoalocalhospitalwitha5-dayhistoryofcough,fever,chills,anddyspnea.Hertemperaturewas38.2℃andphysicalexaminationrevealeddiminishedbreathsoundsintheleftlungfieldandcracklesintherightmid-lungfield.Chestroentgenographydemonstratedbilaterallowerlunginfiltratesandaleftpleuraleffusion.
Question:
1whatisthemostpossiblediagnosis?
2whatareyougoingtodonextinordertoverifyyourdiagnosis?
3whatkindofantibioticsshouldberecommended?
Case4
Male,67Y,chroniccoughandsputumproductionfor10years,exertionaldyspneafor3years,andexacerbationfor2weeks.Thepatienthadoftencoughed,withwhitefoam-likesputumfor10years.Andinrecent2weeks,thesymptomsaggravated,includingsevereshortbreathandwheeze,purulentsputum,limitationofactivity.Cigarettesmokingfor30years,20/d.Physicalfindings:
lightlycyanosedorallip,diminishedbreathsoundanddryralesonauscultinghibaterallung.X-ray:
hibateralpulmonarymarkingsdisordered,diaphragmaticmusclemoveddown.
Question1
Whichisthemostprobablediagnosis?
Abronchialasthma
Bbronchiectasis
CCOPD
DCOPDwithcorpulmonale
Question2
Whichmethodsbelowisthebestchoicefordefinitivediagnosis?
AlungHRCT
Bpulmonaryfunctionaltest
Cdermalallergentest
DDopplerechocardiography
Question3
Whichtherapeuticstrategyisthebesteffectivetorelivesymptom?
Aposturaldrainage
Benhancementofmyocardialcontractilityanddiuresis
Cinhaledglucocorticosteroid
Dbronchodilators
Case5
Male,34Y,gotfever2daysagoforcommoncold,T38.9℃,coughedexpectoratedalittleofyellowsputum,andalsohaddyspnea.Hehadeverdiarrheafor2times.Itwasinefficaciousfororalusecephalosporin.Physicalfindings:
P92/min,R28/min,somnolence,lightlycyanosedorallip,moistralesonauscultinghibateralinferiorlung.WBC9.2×109/L,N87%,bloodserum[Na+]↓.Bloodgasanalysis:
pH7.35,PaO257mmHg.X-ray:
lamellarshadowcanbeseeninsuperiorandinferiorlobeofleftlung,middleandinferiorlobeofrightlung.
Question
1writeoutthemostprobabletypeofpneumonia.
2whichkindofantibioticisthefirstchoice?
Case6
Male,60Y,smokingfor800number-years.Chroniccoughanddyspneafor35years,intermittentedemaoflowerlimbsfor2years.BloodgasanalysishadshowedPaO2at55-60mmHgformanytimes.Recently,thesymptomsaggravatedaftercommoncold,witholiguriaandedemaoflowerlimbsappearing.Onadmission,thepatientshowedtrance,somnolenceandobviouscyanosis.Bloodgasanalysis:
PaO250mmHg,PaCO286mmHg.
Question
1writeoutthediagnosisofthispatient?
2we’llplantotherapythepatientwithtrachealintubationandmechanicalventilation,andtheaimistolowerthePaCO2to__
Anormallevel
Bbelownormallevel
C55-60mmHg
Dretainthepresentstate
Case7
A70yearsoldmalewithahistoryofheavysmokingandmoderatelyseverechronicobstructivepulmonarydiseasehasbeenfeelingpoorly.Hereportscough,chills,pleuriticchestpain,andlow-gradefever.Chestradiographrevealsasmalldenseinfiltrateintherightlowerlobe.Gram-negativestainofthepatient’ssputumrevealsnumerousgram-negativecoccus,manyofwhichoccurinpairs.
1thepathogenicbacteriashouldprobablybe__
Asteptocococuspneumonia
Bhemophilusinfluenzae
Cklebsiellapneumoniae
Dmoraxellacatarhalis
Epseudomonasaeruginosa
2themostappropriatetherapyshouldbe__
Anoantimicrobialtherapyisrequired
Btetracycline
Cciprofloxacin
Dtrimethoprim-sulfamethoxazole
Epenicillin-calvulanicacid
Case8
a63-year-oldmanhaspneumococcalpneumoniawithextensiveair-spaceconsolidationintheleftupperandleftlowerlobes.Hecomplainsofextremeshortnessofbreathwhenpositionedwithhisleftsidedown.AnarterialbloodsampledrawninhispositionshowsaPO2of6.2Kpa(46mmHg),10minutesearlier,anarterialbloodsampledrawnwhilehisrightsidewasdependenthasrevealedaPO2of8.2kp(66mmHg).
ThemostlikelyexplanationforthedropinPO2whenthemanwaslyingonhisleftsideis__
Aincreasedbloodflowtothedependentlung
Breducedventilationtothedependentlung
Cincreasedairwayresistanceinthedependentlung
Daccumulationofinterstitialedemainthedependent
Eincreasedstiffofthechestwallonthedependentlung
Case9
thepatientisa19yearoldmalestudent.herchiefcomplaintisbeingfeverforfourdays,coughingfortwodays.
fourdaysagohefeltcoldthenfeverafterabasketballmatch.thehighesttemperatureisupto40degreeaccompanyingwithchilling.thosesymptomswerenotimprovedbytakingamoxicillinandparacetamol.twodaysago,hebegantocough,accompanyingwithalittlewhitesputumandrightchestpain.X-rayofchestshowsslightlypatchyshadowintheinferiorfieldofrightlungnearthediaphragm.hewasgiventhediagnosisofpneumoniaatlocalhospitalandcephradineintravenouslyfortwodays.butnoimprovementappeared.Now,hewasbadappetite,nausea,withoutvomiting,dilutedstool.heishealthypreviously.
physicalexamination:
T39.5degree,P100permin,R28permin,BP85/60mmHg.Heisconsciouswithfeveringfaceandinbadstate.nosuppurativelesioncanbefoundinhisglossopharyngealpartandskin.percussionoflowerpartofrightlungisdull.Auscultationofthatareacanfounddiminishedbreathsoundwithoutdryormoistrale.theheartrateis100perminwithregularrhythm.Theabdomenissoft,andtheliverispalpitated2cmbelowthecoast,softandtouchingpain.
laboratoryexamination:
WBC3.5g/l,N0.9,L0.1.urineproteinispositive.livetfunctiontestshowselevatedALTandALP.myocardialenzymaticspectrumshowselevatedLDHandCPK.Theconcentrationofsodiuminserumisatthelowerlimitofnormalstandard.legionellaantibodyisnegative.mycoplasmaantibodyisnegative.blood–gasanalysisshowsPH7.50,Pao258mmhg.
X–rayofchestshowslargehigherdensityparchyshadowinthemiddleandinferiorfieldofrightlung.rightcostophragmangledisappears.ECGshowssinaltachycardia.dopplerofheartshowsnormalintracardiacstructureandalittleeffusioninpericardia.
Questions
1whatistheimpressdiagnosis
2whichantibioticsshouldbechosen?
Case10
Thepatientisa38yearsoldfemalepeasant.Herchiefcomplaintisparoxysmalgasping,dyspneafortwodays.Twodaysago,shesuddenlypanted,accompanyingwithbreathlessanddyspnea,whenshewasplantingmushroominanairtightconservatory.Thesesymptomswerenotrelievedaftershelefttheconservatory.Sheishealthypreviously.Physicalexamination:
Thepatientisconscious,orthopnea,sweaty,brokenspeaking,cyanosisofthelops.Wheezecanbeheardthroughoutbothlungs.Heartrateis130perminwithregularrhythm.Blood-gasanalysis:
PH7.472,PaO256mmHg,PaCO2mmHg.Pulmonaryfunctiontestcannotbecarriedoutbecauseofherdyspnea.X-rayofchestshowsbothlungsarehypertranslucent.
Questions
1What’sthediagnosis
2thesymptomofgaspingofthepatientisobviouslyrelievedandthewheezeinbothlungsdiminishedafteradministratingglucocorticoidintravenouslyforfiveyears.Then,WhichexaminationshouldbetakenandWhichdrugshouldbegivenforthepurposeofmaintainingtreatmentforalongtime?
Case11
Thepatientisa45yearsoldmalepeasant.Hischiefcomplaintisbeingfever,coughingwithbloodysputumforhalfamonth.Deterioratingwithlargeamountofyellowfoulsuppurativesputumtwodays.Hebegantosmoketwentyyearsago,twentycigaretteseachday.Histemperatureis38.5degree.Moistralecanbeheardintheinterscapulararea.AuxillarytestshowselevatednumberofWBC,andtheproportionofneutrophilishigh.Thetuberculosisbacteriaandtumorcellinsputumarenegative.X-rayofchestshowspatchyshadowinthebacksegmentofupperlobeofrightlungwithblurredborder.Theseareatranslucentareac