生物信息学选择题Bioinformatics multiplechoice question.docx

生物信息学选择题Bioinformatics multiplechoice question.docx

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生物信息学选择题Bioinformaticsmultiplechoicequestion

生物信息学选择题（Bioinformaticsmultiple-choicequestion）

ThemeaningofUTRis（B）.

A.codingregion

B.noncodingregion

C.lowcomplexityregion

D.openreadingframe

Themeaningofmotifis（D）.

A.motif

B.crossclonalpopulation

C.basepair

D.domain

Themeaningofalgorithmis（B）.

A.logonnumber

B.algorithm

C.alignment

D.analogy

RGPis（D）.

A.onlinehumanMendelgeneticdata

B.nationalnucleicaciddatabase

C.humangenomeproject

D.ricegenomeproject

ThefollowingFastaformatiscorrect（B）.

A.seq1:

agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactccctta

B.>seq1agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactccctta

C.seq1:

agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactccctta

D.>seq1agcggatccagacgctgcgtttgctggctttgatgaaaactctaactaaacactccctta

Ifwearetryingtodosubcellularlocalizationofproteins,weshoulduse（D）.

A.NDBdatabase

B.PDBdatabase

C.GenBankdatabase

D.SWISS-PROTdatabase

ThemeaningofBioinformaticsis（A）.

A.Bioinformatics

B.genomics

C.proteomics

D.epigenetics

InGenBank,thePLNofthecategorycodemeans（D）.

A.mammaliansequence

B.bacterialsequences

C.phagesequences

D.sequencesofplants,fungi,andalgae

Themeaningoforthologis（A）.

A.orthologous

B.paralog

C.directevolution

D.indirectevolution

TheshortsequenceobtainedfromthecDNAlibraryis（D）.

A.STS

B.UTR

C.CDS

D.EST

Themeaningofcontigis（B）.

A.motif

B.crossclonalpopulation

C.basepair

D.domain

TheTAIR（AtDB）databaseis（C）.

A.nematodegenome

B.Drosophilagenome

C.Arabidopsisdatabase

D.Escherichiacoligenome

ThemeaningofORFis（D）.

A.regulatoryregion

B.noncodingregion

C.lowcomplexityregion

D.openreadingframe

MRNA5'endhas（A）structure.

A.hat

B.tail

C.hatsandtails

D.polynucleotide

UsingtheCNKIdatabase（CNKI）tofindthesubjectoftheanalysis,theexpansionproteinfamilyproteinsequencewaspublishedinthethirdissueofjournalbioinformaticsseventhin2008（C）.

A.,page3-5

B.,page93-95

C.,page193-195

D.,page293-295

Atpresent,themainmethodforstatisticalanalysisofmicroarraydatais（C）.

A.chisquaretest

B.correlationanalysis

C.clusteranalysis

TestofnormaldistributionofD.

ThemeaningofSAGEis（A）.

ContinuousanalysisofA.geneexpression

B.polyacrylamidegelelectrophoresis

C.genomeanalysis

D.two-dimensionalelectrophoresisanalysis

Themeaningofdomainis（D）.

A.motif

B.crossclonalpopulation

C.basepair

D.domain

MRNA3'endhas（B）structure.

A.hat

B.tail

C.hatsandtails

D.polycytosine

ThehumannonredundantgenedatabaseinNCBIis（A）.

A.UniGene

B.UniPro

C.UniRef

D.URF

Themeaningofalignmentis（C）.

A.logonnumber

B.algorithm

C.alignment

D.analogy

Entrezusesseverallogicaloperatorstomakethemostbasicrestrictionsonkeywordretrieval（C）

1kindsofA.

2kindsofB.

3kindsofC.

4kindsofD.

Microsatellitemarkersare（C）.

A.RFLP

B.SNP

C.SSR

D.RAPD

ThesubmissionsequencetoGenBank,theprogramusedcanbe（D）.

A.Entrez

B.SRS

C.Medline

D.BankIt

PDBisaprotein（B）.

A.classificationdatabase

B.structuredatabase

C.phantomdatabase

D.domaindatabase

Restrictionfragmentlengthpolymorphismmarkers（A）.

A.RFLP

B.SNP

C.SSR

D.RAPD

ThemeaningofCDSis（A）.

A.codingregion

B.noncodingregion

C.lowcomplexityregion

D.nonregulatoryregion

Theconstructionoftheevolutionarytreetoolis（C）.

A.BLAST

B.ClustalW

C.Mega

D.GCG

Themeaningofanalogyis（D）.

A.logonnumber

B.algorithm

C.alignment

D.analogy

Ineukaryotes,thesequenceofthe5'startcodonAUGofagenecDNAconformsto（A）rules.

A.Kozak

B.AU...AG

C.SD

D.Poly（A）n

Afterthenucleicacidsequenceistranslatedintoaproteinsequencein6strands,thesequenceofproteinsissearched.Thedatabaseusestheprogram（B）.

A.

blastp

b.blastx

c.tblastn

d.tblastx

利用pubmed文献数据查找论文"transgenicplantsofpetuniahybridaharboringthecyp2e1geneefficientlyremovebenzeneandtoluenepollutantsandimproveresistancetoformaldehyde"的第一作者是（d）.

a.xiangt

b.baol

lipc.

zhangqd.

基本局部比对搜素工具是（c）.

a.mega

b.clustalw

c.blast

d.gcg

被誉为"生物信息学之父"的科学家是（d）.

a.dulbecco'smodifiedeagle

b.sanger

c.吴瑞

d.林华安

ddbj的含义是（c）.

a.美国国家生物信息中心

b.欧洲分子生物学实验室

c.日本dna数据库

d.中国基因组研究中心

利用pubmed文献数据查找发表在'nature,2012,487（7405）:

43-45"上的论文题目是（d）.

a.amapofthecisregulatorysequencesinthemousegenome

b.thehumancstcomplexisaterminatoroftelomeraseactivity

c.tumours:

lesslactationmayexplaincancerrise

d.stemcells:

asporadicsuperstate

利用pubmed文献数据查找论文"cancerepigenetics:

frommechanismtotherapy"作者的单位是（c）.

a.universityofcalifornia

b.universityofcolumbia

c.universityofcambridge

d.universityofchicago

单核苷酸标记是（a）.

a.rflp

b.snp

c.ssr

d.rapd

genbank数据库的基本信息单位是（b）.

a.fasta

b.gbff

c.gcg

d.asn.1

omim是（a）.

a.在线人类孟德尔遗传数据库

b.国家核酸数据库

c.人类基因组计划

d.水稻基因组计划

多序列比对工具是（b）.

a.blast

b.clustalw

c.mega

d.gcg

embl的含义是（b）.

a.美国国家生物信息中心

b.欧洲分子生物学实验室

c.日本dna数据库

d.中国国家基因组研究中心

accessionnumber的含义是（a）.

a.登录号

b.算法

c.比对

d.类推

est的含义是（a）.

a.表达序列标签

b.序列标签位点

c.高通量基因组序列

d.人工合成序列

利用中国知网文献数据库（中国知网）查找论文题目是"黄瓜对不同温度逆境的抗性研究"作者的单位是（a）.

a.天津市黄瓜研究所

b.中国农业科学院

c.中国科学院

d.中国农业大学

没有直接参与完成人类基因组计划的国家是（c）.

a.英国

b.中国

c.俄罗斯

d.德国

blast结果中hsp的含义是（d）.

a.空位

b.期望值

c.过滤

d.高分配对片段

genbank登录号为scu49845的序列,其dna产度是（d）.

a.1028bp

b.9bp

c.4028bp

d.5027bp

genbank数据库中的登录号aar19268是（a）.

a.水稻的dna序列

b.水稻的蛋白质序列

c.人类的dna序列

d.人类的蛋白质序列

在真核生物的一个基因内含子两端,即外显子/内含子拼接边界处,其符合（b）规则.

a.kozak

b.the...ag

csd

d.poly（a）n

蛋白质信号肽的预测工具有（d）.

a.nnpredict

b.predictprotein

c.singald

d.singalp

basepair的含义是（c）.

a.基序

b.跨叠克隆群

c.碱基对

d.结构域

proteomics的含义是（c）.

a.生物信息学

b.基因组学

c.蛋白质组学

d.表观遗传学

根据大量est具有相互重叠的性质,通过计算机算法获得cdna全长序列,这种克隆基因的方法是（b）.

a.重叠克隆

b.电子克隆

c.基因步移

d.基因重组

隐马尔科夫模型的代号是（a）.

a.hmm

b.cdd

c.htgs

d.gss

entrez数据库中的剪贴板的容量是（a）.

a.500条记录

b.1000条记录

c.5000条记录

d.

10000records

ThemeaningofUTRis（B）.

A.codingregion

B.noncodingregion

C.lowcomplexityregion

D.openreadingframe

GenBankis（B）.

A.onlinehumanMendelgeneticdata

B.internationalnucleicaciddatabase

C.humangenomeproject

D.ricegenomeproject

UsingtheCNKIdatabase（CNKI）,thetitleofthispaperis"theultrastructureandphotosyntheticcharacteristicsofleafchloroplastsofcucumberhairlessmutants",thefirstauthoris（A）.

A.CaoChenxing

B.ZhangSong

C.GuoHongyun

D.GuoYankui

Accordingtothestudy,therealcodingregionofproteinsinthehumangenomeisonlyDNA（B）.

A.1-2%

B.3-5%

C.5-10%

D.10-20%

ThemeaningofLCRis（C）.

A.codingregion

B.noncodingregion

C.lowcomplexityregion

D.openreadingframe

Ifwearetryingtodosubcellularlocalizationofproteins,weshoulduse（D）.

A.NDBdatabase

B.PDBdatabase

C.GenBankdatabase

D.SWISS-PROTdatabase

UsingPubMedliteraturedatatofindpapers,"A,whole-cell,computational,model,predicts,phenotype,from,genotype"waspublishedintheCellJournal（C）.

A.,Vol.first,issuefiftieth,page389-391

B.,Vol.first,issuefiftieth,page389-401

C.,Vol.second,issue150th,page389-401

D.,Vol.second,issue125th,page389-391

Themeaningof[ST]inproteinmotif（motif）is（C）.

A.aminoacidisST

B.aminoacidsareSandT

C.aminoacidsareSorT

D.removeanyaminoacidsexceptSandT

Buildphylogenetictreesthatshouldbeused（C）.

A.BLAST

B.FASTA

C.UPGMA

D.FTP

PIRis（D）.

A.nucleicaciddatabase

B.mRNAdatabase

C.bootdatabase

D.proteindatabase

Whatarethemainwaysinwhichtheoutputgraphisusedinmicroarrayanalysis?

（A）

A.colorcubearrayrepresentation

TheB.isrepresentedinahoneycombshape

TheC.isrepresentedinblackandwhitedots

D.isrepresentedincolorlines

Whichofthefollowingisnotpartofthepromoterstudy?

（A）

A.CpGIslandforecast

B.transcriptionstartpointprediction

C.glycosylationmodification

D.methylationdetection

Whatkindoftoolsdoesbioinformaticsmainlyusetorealizethestorage,retrievalandanalysisofbiologicalinformationinlifescienceresearch?

（A）

A.computer

B.iPhone

C.satellite

D.mobilephone

ThemeaningofHTGSis（C）.

A.expressedsequencetags

B.sequencetaggedsite

C.highthroughputgenomesequences

D.syntheticsequence

ThemeaningofSTSis（B）.

A.expressedsequencetags

B.sequencetaggedsite

C.highthroughputgenomesequences

D.syntheticsequence

UsingtheCNKIdatabase（CNKI）tofindthetitleofthispaper,"theinfluenceoflightandtemperaturefactorsinsolargreenhouseontheultrastructureandfunctionofcucumberchloroplasts"ispublishedintheJournalB.

A.JournalofHorticulture

B.JournalofAppliedEcology

C.Journalofecology

D.Geneticsjournal

UsingthePubMedliteraturedatatofindpapersEnhancing,phytoremediation,through,the,use,of,transgenics,and,endophytes,publishedinthejournalis（A）.

A.NewPhytol

B.Gene

C.Nature

D.PlantPhsiol

HGPis（C）.

A.onlinehumanMendelgeneticdata

B.nationalnucleicaciddatabase

C.humangenomeproject

D.ricegenomeproject

InDNA,theTmvalueisdirectlyproportionalto（B）content.

A.G+A

B.G+C

C.T+C

D.A+T