专业英语电子教案Word格式文档下载.docx

专业英语电子教案Word格式文档下载.docx

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重点

药物的概念，体内过程及中医理论的专业词汇和表达方式

难点

体内过程的英文描述和相关词汇

思考题

Whatwillhappentoadrugaftertheabsorption?

参考文献

MedicinalChemistry

系部

化学制药系

授课教师

房静

教学方案

（共1页、第1页）

课程名称：

专业英语课程内容：

药学专业英语

教师名称：

房静教学日期：

2011-2012学年第一学期

授课对象：

09化学制药1-3班教材版本：

《制药专业英语》第一版

授课方式：

讲授学时数：

4听课人数：

本单元或章节的教学目的与要求：

掌握药物分类，不良反应，作用机制等专业词汇和表达方法

授课主要内容及学时分配

Unit1Whatisadrug？

1definitionandmedicinalandnon-medicinaldrugs1学时

2Classificationandnamesofdrugs1学时

3Differentmechanismsofdrugaction1学时

Self-assessment1学时

重点、难点及对学生要求（包括熟悉、了解和自学）

熟悉课程结构、讲授部分的课文内容、课后重点词汇；

了解相关词汇；

自学补充阅读材料

外语词汇：

PharmaceuticalEnglish,treatment,prevention,diagnosis,etc.

辅助教学情况

ppt

复习思考题WhatsthepurposeofstudyingPharmacyEnglish？

Unitonewhatisadrug

Warm-upquestions:

1whatisyourdefiniationofdrugs?

2whattypesofdrug/medicinehaveyouused?

Vocabulary

Synthetic合成的,综合的,人造的（反义词:

NAUTURAL天然的）

Phsiological生理的

Pathological病理的

Cure治愈

Treatment治疗

Prevetion预防

Diagnosis诊断

Cannabis大麻

Heroine海洛因

Cocaine古柯碱,可卡因

Caffeine咖啡因

Nicotine尼古丁

Pregnant怀孕的,妊娠的

Fetalmalformation胎儿畸形,畸胎

Metabolism代谢

renalclearance肾清除率

Controindicate禁忌

Molecule分子

Molecular分子的

Genericname通用名

Brandname商品名

Pharmacopoeia药典

Patent专利

Expire到期

Retain保留,保持

Inevitable不可避免的

Cellular细胞的

Macromolecule大分子

Enzyme酶

Receptor受体

Modification改变,修改

Molecularmordification分子修饰

Inhibition抑制

Socialdrugsthetermreferstotheagentstakennotforthetreatmnetofdisease,butforpleasureorotherpersonalreasons.指非用于治疗目的,而是用于娱乐和其他个人目的的药物,如酒精,烟草,非法毒品等.

Pronetoequalstotendingto易于….的,有…..倾向的

补充词汇：

Pharmacology药理学

Pharmacy药学

Pharmaceutics药剂学

PharmaceuticalAnalysis药分

Medicinalchemistry药化

Naturalproducts天然产物

Pharmacognosy生药学

TEXT

Whatisadrug?

Adrugisanynaturalorsyntheticsubstancethataltersthephsiologicalstateofalivingorganism.Drugscanbedividedintotwogroups:

1medicinaldrugs

2non-medicinals/drugsocialdrugs

Drugabuse药物滥用

drugscanrarelyexertaideallyselectiveaction.Thereisalwaysariskofsideefectsassociatedwiththeuseofdrug.Herearethefourgroupsofpeoplethataremorepronetheadverseeffects:

1pregnantweman

2breast-feedingweman

3patientswithliverorkidneydisease

4theelderly

Drugnamesandclassification

Asingledrugcanhaveavareityofnamesandbelongtomanyclasses.

Factorsusedtoclassifyingdrugs:

1pharmacotheropeuticactons

2pharmaclogicalactions

3molecularactions

4chemicalnature

Twotypesofname:

1genericnameisthatappearsintheofficialnationalpharmacopoeia（onlyoneinacountry）

2brandnamecanbevariousinacountry.

Howdodrugswork?

Adrugcausesachangeofphsiologicalfunctionbyinteractionwiththeorganismatthechemicallevel.

Certaindrugsworkbymeansoftheirphysicalpropertiesandhaveanon-specificmechanismofaction.Forthisreason,theymustbegiveninamuchlargerdose.

Mostdrugsproducetheireffectsbytargetingspecificcellularmacromolecules.ThismayinvlovemodificstionofDNA/RNAfuntion,inhibitionoftransportsystemorenzymeor,morecommonly,actiononreceptors.

Selfassessment

Skipped

Readingmaterial

Routesofdrugadministration.

掌握药物体内过程和蛋白结合等专业词汇和表达方法

Unit2Fateofdrugafterabsorption

Vocabulary1学时

1Bindingofdrugtoplasmaprotein

2metabolismandexcretionofbounddrug1学时

3Interactionofdrugco-existence1学时

Absorption,serum,plasmaprotein,treatmentregimen，etc.

复习思考

Whatistheinfluenceoftheadditionaldrug？

1Doyouknowhowthedrugsdetthroughthehumanbody?

3Whathappenstothedruginthebody?

Absortion吸收

Bound结合的

Protein蛋白质

Naproxen萘普生

Plasma血浆

Penicillin青霉素

Amoxicillin氨苄青霉素

Concentration浓度

Filter过滤

Glomeruli肾小球

Penetrate渗透,穿过

Reservior储库

Depot仓库,补及站

Saturation饱和

Serum\血清

Albumin白蛋白

Phenytion苯妥英

Simultaneous同步的,与此同时的

Salicylate水杨酸盐

Thyroid甲状腺

Thyroxin甲状腺素

Hormone激素

Anti-抗-

Inflammatory炎症的,发炎的

Coagulate凝结

Diaetic糖尿病的

Sulfonamide磺胺类药物

Intensity’强度

Warfarin华法林

\triple三倍,成三倍增长

regimen治疗方案

monitor检测,监控

component组分,成分

accumulate累积,积蓄

permeability透过性

capability能力

affinity亲和力

solubilityinlipids脂溶性（脂肪中的溶解度）

相关词汇补充：

-ate表示酯或盐类

-one表示酮类

-nol表示醇类

-ane烷类

-ene烯类

Methyl一甲基methane甲烷methanol甲醇（依此类推）

Ethyl二乙基

Propyl三丙基

Butyl四丁基

Pentyl五戊基

Hexyl

Heptyl

Octyl

Nanyl

Decyl

药物代谢的四大部分：

Absorption吸收metabolism代谢

Distribution分布excretion排泄

Text

Fateofdrugafterabsorption

Afterabsorptionintothegeneralcirculationfromanyrouteofadministration,adrugmaybecomeboundtobloodproteinsanddelayeditspassageintothesurroundingtissues.Thedegreeodadrugbindingtobloodproteinisdifferent,itcanbehighlybound,lowboundorunbound.

Thedegreeofthisbingdingcanbeexpresedasafraconorasapercentageoftheboundconcentrationtothetoalconcetration,boundplusunbound.（refertothetextookfortheequation）

Thus,ifoneknowstwoofthethreetermsofthisequation,thenthethirdonecouldbecalculated.Drugshavivinganalphavaluegreaterthan0.9zreconsideredtobehighlybound,anddrugshavinganalphavaluelessthan0.2arelittleproteinbound.

Bounddrugisnertherexposedtothebody’sdetoxificationprocessnorisitfilteredthroughtherenalglomeruli.Bounddrugisthereforereferedtoastheinactveportionintheblood,andthoseunbounddrugaresocalledactivebloodportion.Boundbloodportionservesasthereserviorordepotofthedrug,whichwillreleasethedruginthefreeformwhentheleveloffreedruginthebloodisnotadequatetoensuretheproteinsaturation.Adrugthatishighlyboundwillstayinthebodyforlongerperiodoftimeandrequireslessfrequentdosageadministration.Evideninsuggeststhattheconcentrationofserumalbumindecreasessignificantlythemaybeclinicallyimportantforthosedrugsthatarestrongproteinbound.Withoutadownwarddosageadjustment,therecouldbeanincreaesedincidenceofadverseeffects.

Adrug’sbindingtobloodproteinmaybeaffectedbythesimutaneouspresenceofaseconddrugormoredrugs.Theadditionaldrugsmayresultindrugactionordurationquitedissimilartothatfoundwheneachisadministeredalone.Wetakeseveraldrugsforinstancetoillustratethis,theseincludesalicylates,phenydutazone,warfarin.

Inthesamemannerastheybindtothebloodprotein,theyalsobindtospecificcompnentsofcertaincells.Thus,drugisnotdisributeduniformlyamongallthecellsinofthebody,rathertendtopassfromthebloodintothetissuefluid,andmayaccumulatincertaincellsaccordingtotheirpermeabilitycapabilitiesandtheirphysicalandchemicalaffinity.Thisaffinityforcertaibodysiteinfluencetheiractionfortheymaybebroughtintocontactwithreactivetissuesordepositedinplaceswheretheymaybeinactive.Manydrugs,becauseoftheiraffinityforandsolubilityinlipids,arefoundtobedepositedinthefattybodytissue,therebycreatingastorageplacefromwherethedrugcanbeslowlyreleasedintoothertissues.

Self–assessment

Skipped.

ReadingmaterialExcretionofdrugs（homework）

掌握中医基础理论，辨证论治整体观等专业词汇和表达方法

Unit3TCM

1thingsaboutTCM，thehistoryandsituation1学时

2twocharacteristicsofTCM1学时

TraditionalChineseMedicine,etiology,holisticpointofview,etc.

Pptvedio

复习思考题

WhatdoyouknowofYin-Yang？

Unit3TraditionalChineseMedicine（TCM）

1whatdoyouknowaboutTCM?

2Haveyouevertriedit?

talkaboutyourexperience

Etiology病因学,病源学

symptomcomplex症候群

Channels经脉

Collaterals络脉

Holistic整体的,全盘的

Entity实体

Dysfunction功能紊乱,机能不良

Vessel血管,导管

Acupuncture针灸

Geographical地理的

Constitution体质

Syndrome综合症

Identify识别,鉴别

Causative导致发生的,成为原因的

Confrontation对抗

Manifestation表现,症状

Analogy类似物,类推

1.中医的脏腑包括五脏:

心肝脾肺肾;

六腑:

胆,胃,小肠,大肠,膀胱,三焦.与西医中的内脏有区别.

2.中医认为致病因素和非致病因素之间对抗导致疾病,因此,课文中的’toOBTAINTHECONCLUSIONSABOUTTHECONFRONTATIONBETWEENPATHOGENICANDANTI-PATHOGENICFACTORS’可译为辨病机.

IntraductiontoTCM

ThebasictheoriesofTrditionalChineseMedicinedescribe:

1physiologyandpathologyofthehumanbody人体生理病理学

2disaseetiology疾病的病源学

3diagnosis诊断学

4differentationofsyndromes辩证（施治）

Theseincludetheoriesof:

1Yin-Yang阴阳

2FiveElements五行

3zang-fu脏腑

4channels–collaterals经络

4qi,blood气血

5bodyfluid津液

6methodsofdiagnosis诊断方法

7differentationofsymptom-complexes症侯群的分析辨别

TraditionalChinesemedicaltheoriespossesstwooutstangdingfeatures:

1theholisticpointofview整体观

2theapplicationoftreatmentaccordngtothedifferentiationofsyndromes.

辨证施治

InTCM,thezang-fuorgansarethecoreofthehuamnabodyasanentiy,inwhichsenseorgansandtissuesareconnectedthroughanet