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Sadly,in2009,5yearslater,Lauralostherfather.Beforehedied,Laurawenttoahospitalappointmentwithhim,wheredoctorsmentionedthathisformofAlzheimer’swasgenetic,meaningtherewasafiftyfiftychancethatshehadinheritedit.ForseveralyearsLauraagonisedoverwhethertobetested,finallyfindingoutinAugust2017thatshehastheAPPgene,meaningthat,likehim,shewilldeveloptheconditionwithinadecade.

Atfirst,shestruggled,feelingasifshelackedpurpose.Then,duringasleeplessnightinthesummerof2018,shedecidedataround2a．m.toenterthe2019LondonMarathonsponsoredbythecharitiesAlzheimer’sSocietyandAlzheimer’sResearchU．K.

ShehopedtostarttheconversationaroundearlyonsetAlzheimer’sandtoencouragepeopletotalkaboutitmoreopenly.“IrememberwhenDadwasill,peoplewouldn’tknowhowtoreactanditallfeltveryhiddenaway,butIwanttobehonestandopen.”Sheadded,“Themoreinformationwecanget,thelessofataboo（忌讳）thiswillfeel.Thatsaid,thesupportI’vereceivedsofaraftergoingpublichasbeenamazing—that’swhatiscarryingmethrough.”

【解题导语】　LauraSides在读大学期间，父亲患上了阿尔茨海默病，她休学悉心照料父亲直到他去世；

后来她被医生告知自己在十年后也会患上同样的病。

短暂的痛苦之后，她便振作了起来，积极面对生活，参加马拉松比赛，并且进行阿尔茨海默病方面的公开演讲，鼓励人们公开谈论这种病，而不是回避它。

1．Lauranoticedherfather’sdementiawhen________.

A．herfathertoldherhisconditioninperson

B．peoplenearbyinformedherofherfather’scondition

C．herfatherforgothisownbirthdayparty

D．herfatherforgottoattendher21yearoldbirthdayparty

D　解析：

细节理解题。

根据第一段中的“Then,Icamehomeformy21stbirthday...That’swhenIknewsomethingseriouswashappening.”可知，Laura的父亲忘记参加女儿的21岁生日会，在那时Laura意识到父亲已患病，故选D。

2．Theunderlinedword“agonised”inparagraph4probablymeans“________”．

A．excited　　B．struggled

C．shockedD．delighted

B　解析：

词义猜测题。

根据上文中的“therewasafiftyfiftychancethatshehadinheritedit”可知，医生告知Laura，她有百分之五十的患病概率，并结合画线词所在句中的“whethertobetested”可知，此处表示Laura多年来苦苦思索是否去检查一下，与B项词义接近。

3．Laurastartedtheopentalkinthehopeof________.

A．gettingpeopletotalkaboutAlzheimer’sopenly

B．earningsomemoneytohelptreatherAlzheimer’s

C．makingherselfstrongertofightagainstAlzheimer’s

D．raisingfundsforcharitiesAlzheimer’sSocietyandAlzheimer’sResearchU．K.

A　解析：

根据题干中的关键词opentalk定位到文章的最后一段。

根据该段首句“ShehopedtostarttheconversationaroundearlyonsetAlzheimer’sandtoencouragepeopletotalkaboutitmoreopenly.”可知，作者公开谈论阿尔茨海默病是为了鼓励人们公开谈论此病，故选A。

4．WhichwordscanbestdescribeLaura?

A．Caringandpositive.B．Carefulandhonest.

C．Patientandcautious.D．Devotedandmodest.

推理判断题。

通读全文内容可知，Laura在得知父亲患阿尔茨海默病后休学来悉心照料他直至他去世，后来得知自己也会得阿尔茨海默病后，挣扎后便振作起来，先是决定参加马拉松比赛，接着针对这种病进行公开演讲，鼓励人们更加公开地谈论它，而不是回避它。

由此可知，作者是一个关心他人且积极向上的人，故选A。

【难句分析】　Beforehedied,Laurawenttoahospitalappointmentwithhim,wheredoctorsmentionedthathisformofAlzheimer’swasgenetic,meaningtherewasafiftyfiftychancethatshehadinheritedit.

分析：

本句是一个主从复合句。

Before引导了一个时间状语从句；

关系副词where引导一个非限制性定语从句，修饰先行词ahospitalappointment；

该定语从句中，that引导宾语从句，作mentioned的宾语；

meaning...shehadinheritedit是现在分词短语作伴随状语，其中therewasa．..it是省略了连词that的宾语从句，且thatshehadinheritedit作chance的同位语。

译文：

在他去世前，劳拉陪他去医院，医生提到他的阿尔茨海默病是基因型的，这就意味着劳拉有百分之五十的概率遗传这个病。

B

郑州高三质检）Foraslongaswe’veknownaboutit,humanshavesearchedforacureforcancer.Acrosstheworld,countlessamountsoftimeandmoneyhavebeenspentonresearchingawaytostopthisterribledisease.Butnow,itseemsliketheanswercouldhavebeeninsideourownbodiesthewholetime.

Recently,theFoodandDrugAdministration（FDA）intheU．S.,agovernmentagencythat’sresponsibleforhealthcare,approvedanewformofgenetherapythatcouldmeantheendofacertaintypeofcancer.

Thetherapyallowsscientiststo“train”theimmune（有免疫力的）cellsofsickpatientstofightleukemia—aformofbloodcancerthatmostlyaffectsyoungpeople.

Theexcitingnewtreatmentworksbyremovinghealthyimmunecellsfromthepatient,knownasTcells,whicharethenchangedtobeableto“huntdown”cancercells.

Thecellsarethenputbackintothepatientbeforetheybegintogetridofthepatient’sleukemiaovertime,similartohowthebodyfightsoffotherillnesses.

“Thisistrulyanexcitingnewdayforcancerpatients，”LouisJ.DeGennaro,presidentofTheLeukemia&

LymphomaSociety,saidinanewsrelease.

Upuntilnow,alongandpainfulmarrowtransplant（骨髓移植）wastheonlyoptionformanyleukemiapatients.

Inthisprocedure,healthybloodcellsaretakenfromadonorandplacedintothesickpatient,whoalsohastogothroughchemotherapy（化疗）toallowtheirbodytoadjusttothenewcells.

Butwitharecoveryrateofaround83%—accordingtoanewsreleasepublishedbytheFDA—it’shopedthatthedaysofpainfultripstothehospital,orevendeath,areoverforleukemiasufferers.

“We’reenteringanewfrontierinmedicalinnovationwiththeabilitytoreprogramapatient’sowncellstoattackadeadlycancer，”FDArepresentativeScottGottliebsaidintherelease.“Newtechnologiessuchasgeneandcelltherapiesholdthepotentialtotransformmedicineandourabilitytotreatandevencuremanyincurableillnesses.”

【解题导语】　治愈癌症是医学界的难题，大量的时间和金钱投入到研究一种阻止这种可怕疾病的方法上。

现在一种新的基因疗法给人们带来了治愈白血病的希望。

该疗法通过培养病人体内的有免疫力的细胞来对抗白血病。

5．Whatistheauthor’smainpurposeinwritingthepassage?

A．Tocomparedifferentwaysofcuringleukemia.

B．Toreportonabreakthroughincancertreatment.

C．Toexplorethepotentialofgeneandcelltherapies.

D．Toshowscientists’effortsinsearchofacureforcancer.

写作意图题。

根据第二段“Recently,theFoodandDrugAdministration（FDA）intheU．S.,agovernmentagencythat’sresponsibleforhealthcare,approvedanewformofgenetherapythatcouldmeantheendofacertaintypeofcancer.”并结合全文其他内容可知，本文主要介绍了治疗癌症的一项突破——一种新的基因疗法，故B项正确。

6．Howdoesthenewtreatmentforleukemiawork?

A．ByusingchangedTcellstodestroycancercells.

B．Byreplacingsickbloodcellswithhealthyones.

C．Byremovingsickbloodcellsduringamarrowtransplant.

D．Byusingchemotherapytoimprovethepatient’simmunesystem.

根据第四段的内容可知，该疗法通过改变后的T细胞来对抗身体内的癌细胞，从而达到治疗目的。

7．Whatcanbeinferredaboutthenewtherapyforleukemiasufferers?

A．Itcansavethemmanymoretripstothehospital.

B．Itcanimprovetheirabilitytofightoffallkindsofcancer.

C．Itcangivethemabetterchanceofsurvivalandrecovery.

D．Itcanreducetheirpainintheprocessofthemarrowtransplant.

C　解析：

根据倒数第二段“Butwitharecoveryrateofaround83%—accordingtoanewsreleasepublishedbytheFDA—it’shopedthatthedaysofpainfultripstothehospital,orevendeath,areoverforleukemiasufferers.”可知，根据美国食品和药物管理局发布的新闻，利用这一方法的白血病患者的治愈率约为83%，由此可知，这一方法有望给白血病患者带来更好的存活和康复机会，故C项正确。

8．WhatisScottGottlieb’sattitudetowardsgeneandcelltherapies?

A．Doubtful.B．Optimistic.

C．Worried.D．Casual.

观点态度题。

根据最后一段中ScottGottlieb所说的话“Newtechnologiessuchasgeneandcelltherapiesholdthepotentialtotransformmedicineandourabilitytotreatandevencuremanyincurableillnesses.”可知，ScottGottlieb认为，像基因和细胞疗法这样的新技术有可能改变医学，改变我们治疗甚至治愈许多无法治愈的疾病的能力。

由此可知，ScottGottlieb对基因和细胞疗法的态度是乐观的，故B项正确。

【难句分析】　Recently,theFoodandDrugAdministration（FDA）intheU．S.,agovernmentagencythat’sresponsibleforhealthcare,approvedanewformofgenetherapythatcouldmeantheendofacertaintypeofcancer.

句中that’sresponsibleforhealthcare为that引导的定语从句，修饰先行词agovernmentagency;

thatcouldmeantheendofacertaintypeofcancer为that引导的定语从句，修饰先行词anewformofgenetherapy,that在从句中作主语。

最近，美国食品和药物管理局，一个负责医疗的政府机构，批准了一项新的基因疗法，该疗法可能意味着某种类型的癌症的终结。

Ⅱ.完形填空

新疆维吾尔自治区适应性测试）WhatIhavelearnedwithmythreeteensisthis:

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