FTD patients were impaired by lexicalsemantic syntactic and more especially by pragmatic problems.docx

1、FTD patients were impaired by lexicalsemantic syntactic and more especially by pragmatic problems138The impact of electronic medical record systems on outpatient workflows: A longitudinal evaluation of its workflow effectsOriginal Research ArticleInternational Journal of Medical Informatics, Volume

2、79, Issue 11, November 2010, Pages 778-791Arun Vishwanath, Sandeep Rajan Singh, Peter WinkelsteinShow preview| Related articles|Related reference work articles Purchase$ 31.50139A uniform object-oriented solution to the eigenvalue problem for real symmetric and Hermitian matricesOriginal Research Ar

3、ticleComputer Physics Communications, In Press, Corrected Proof, Available online 25 November 2010Mara Eugenia Castro, Javier Daz, Camelia Muoz-Caro, Alfonso NioShow preview| Related articles|Related reference work articles Purchase$ 31.50140The Fedosov *-product in MathematicaOriginal Research Arti

4、cleComputer Physics Communications, Volume 181, Issue 3, March 2010, Page 704Jaromir TosiekShow preview| Related articles|Related reference work articles Purchase$ 31.50141Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: Enhanced gene silencing activity by th

5、e cooperative effect of tertiary and quaternary amino groups in the coreOriginal Research ArticleJournal of Controlled Release, Volume 146, Issue 3, 15 September 2010, Pages 378-387Atsushi Tamura, Motoi Oishi, Yukio NagasakiShow preview| Supplementary content| Related articles|Related reference work

6、 articles Purchase$ 31.50Graphical abstract142Code C# for chaos analysis of relativistic many-body systemsOriginal Research ArticleComputer Physics Communications, Volume 181, Issue 8, August 2010, Pages 1464-1470I.V. Grossu, C. Besliu, Al. Jipa, C.C. Bordeianu, D. Felea, E. Stan, T. EsanuShow previ

7、ew| Related articles|Related reference work articles Purchase$ 31.50143Comparison of methods for integrating biological and physical data for marine habitat mapping and classificationOriginal Research ArticleContinental Shelf Research, Volume 30, Issue 16, 30 September 2010, Pages 1717-1729E.J. Shum

8、chenia, J.W. KingClose preview| Related articles|Related reference work articles AbstractAbstract | Figures/TablesFigures/Tables | ReferencesReferences AbstractAn important first step in marine spatial planning and ecosystem-based management efforts is the creation of benthic habitat maps that allow

9、 scientists and managers to understand the distribution of living and non-living resources on the seafloor. However, the location of boundaries between and composition of habitats is highly dependent on the approach taken to integrate abiotic and biotic information. The purpose of this study was to

10、test “top-down” and “bottom-up” approaches for integrating physical and biological data derived from commonly used sub-tidal benthic mapping tools to create a habitat map compatible with the US Coastal and Marine Ecological Classification Standard (CMECS). We found that a top-down framework, where w

11、e tested for differences in macrofauna assemblages among side scan sonar facies, defined two broad-scale and general habitats. Using the bottom-up approach, where patterns in abiotic and biotic variables were examined with multivariate statistics (BEST, LINKTREE, ANOSIM, SIMPER), we generated seven

12、biotopes based on the macrofauna abundance, percent sand, water depth, and backscatter standard deviation that corresponded well to, but provided more fine-scale detail than the top-down habitats. We were able to use the statistical relationship between abiotic variables and macrofauna assemblages i

13、n the LINKTREE to predict the spatial distribution of assemblages over 50% of the study area. We created a local catalogue of biotopes specific to our study area that contributes to the CMECS library. In addition, we were able to fully map CMECS Geoform, Surface Geology, and Biotic Cover Components.

14、 This mapping effort represented real progress toward reconciling the “data density mismatch” between physical and biological mapping methods, and it provided further evidence that using a bottom-up methodology preserves speciesenvironment relationships.Article Outline1. Introduction2. Methods 2.1.

15、Acoustic data2.2. Bathymetry2.3. Bottom samples 2.3.1. Sediment properties2.3.2. Macrofauna assemblages2.4. Integration of acoustic data with sediment and macrofauna data 2.4.1. Top-down approach: do the acoustic facies describe distinct macrofauna assemblages?2.4.2. Bottom-up approach: which acoust

16、ic and abiotic variables are related to patterns in macrofauna assemblages?2.5. Mapping and classification3. Results 3.1. Acoustic data3.2. Macrofauna assemblages3.3. Data integration 3.3.1. Top-down3.3.2. Bottom-up3.4. Mapping3.5. Classification 3.5.1. Surface geology component, biotic cover compon

17、ent (SGC, BCC)3.5.2. Geoform component (GFC)4. Discussion 4.1. Acoustic data4.2. Integration approaches4.3. Bioticabiotic relationships and biological assemblage prediction4.4. Habitat classification5. ConclusionsAcknowledgementsReferencesPurchase$ 41.95144International collaboration between US and

18、Thailand on a clinical trial of treatment for HIV-associated cryptococcal meningitisOriginal Research ArticleContemporary Clinical Trials, Volume 31, Issue 1, January 2010, Pages 34-43L.O. Zimmer, T.L. Nolen, S. Pramanpol, D. Wallace, M.E. Walker, P. Pappas, P. ChetchotisakdClose preview| Related ar

19、ticles|Related reference work articles AbstractAbstract | Figures/TablesFigures/Tables | ReferencesReferences AbstractBackgroundInternational clinical trials can provide scientific and logistic benefits in spite of the many challenges. Determining whether a country, especially a developing country,

20、is an appropriate location for the research should include in-country consultation and partnering to assess its social value for the population; that treatments are relevant for the population under study; and that the research infrastructure and ethical oversight are adequate. Collaboration increas

21、es the likelihood of study success and helps ensure that benefits accrue to recruited populations and their community. PurposeThis paper describes our experiences on a bi-national study and may provide guidance for those planning to engage in future collaborations. MethodsA Thai and United States te

22、am collaborated to develop and implement a phase II clinical trial for HIV-associated cryptococcal meningitis to assess safety and tolerability of combination therapy vs. standard treatment. Clinical and cultural differences, regulatory hurdles and operational issues were addressed before and during

23、 the study to ensure a successful collaboration between the 2 groups. ResultsThe international multicenter study allowed for more rapid enrollment, reduced costs to complete the study, sharing of the benefits of research, greater generalizability of results and capacity building in Thailand; quality

24、 metrics in Thailand were equivalent to or better than those in the U.S. ConclusionsConducting successful clinical trials internationally requires early and ongoing collaboration to ensure the study meets sites requirements and expectations, conforms to varying national regulations, adheres to data

25、quality standards and is responsive to the health needs of studied populations.Article Outline1. Introduction 1.1. Disease and trial background2. Methods 2.1. Selection of overseas population2.2. Development of study infrastructure and design and implementation 2.2.1. Protocol development2.2.2. Site

26、 assessment, training and protocol refinement2.2.3. Study materials and processes2.2.4. Shipping of drug and supplies2.3. Ethical oversight2.4. Ongoing oversight of site performance3. Quality of study results 3.1. Measures of study implementation and subject disposition and compliance3.2. Data submi

27、ssion3.3. Data quality4. Discussion 4.1. Benefits4.2. Challenges5. ConclusionsConflict of interest statementAcknowledgementsReferencesPurchase$ 41.95145Development of inhibitory control among prenatally cocaine exposed and non-cocaine exposed youths from late childhood to early adolescence: The effe

28、cts of gender and risk and subsequent aggressive behaviorOriginal Research ArticleNeurotoxicology and Teratology, Volume 33, Issue 1, January-February 2011, Pages 47-60David J. Bridgett, Linda C. MayesShow preview| Related articles|Related reference work articles Purchase$ 31.50146Plasma control sys

29、tem upgrade and increased plasma stability in NSTXOriginal Research ArticleFusion Engineering and Design, Volume 85, Issues 3-4, July 2010, Pages 447-450D. Mastrovito, D. Gates, S. Gerhard, J. Lawson, C. Ludescher-Furth, R. MarsalaShow preview| Related articles|Related reference work articles Purcha

30、se$ 27.95147The impact of the new technologies in foreign language instruction our experienceOriginal Research ArticleProcedia - Social and Behavioral Sciences, Volume 2, Issue 2, 2010, Pages 1185-1189Anisoara PopClose preview| PDF (166 K) | Related articles|Related reference work articles AbstractAbstract | ReferencesReferences AbstractAlthough XXIst century education has become increasingly permeable to technology helping students to acquire skills needed to exist in a highly technological knowledge-based society, foreign language instruction is still resistant to employment o