JPharmBiomedAnal投稿指南Word格式.docx

1、If excerpts from other copyrighted works are included, the Author（s） must obtain written permission from the copyright owners and credit the source（s） in the article. Elsevier has preprinted forms for use by Authors in these cases: contact Elseviers Rights Department, Oxford, UK: phone （+44） 1865 84

2、3830, fax （+44） 1865 853333, e-mail permissions. Requests may also be completed online via the Elsevier homepage, This journal is an international medium for the publication of original research reports and authoritative reviews on pharmaceutical and biomedical analysis. It covers the interdisciplin

3、ary aspects of analysis in the pharmaceutical and biomedical sciences, including relevant developments in analytical methodology, instrumentation, computation and interpretation. Submissions on novel applications focussing on drug purity and stability studies, pharmacokinetics, therapeutic monitorin

4、g, metabolic profiling; drug-related aspects of analytical biochemistry and forensic toxicology; quality assurance in the pharmaceutical industry are welcome. Since classical UV-VIS methods （including derivative spectrophotometric and multi-wavelength measurements）, solvent extraction, basic electro

5、analytical methods, titrimetry, etc. are well established, studies in such areas are accepted for publication in exceptional cases only, if a unique and substantial advantage over presently known systems is demonstrated. Studies reported should be supported by a demonstration of the application of t

6、he method to real samples. No papers dealing with the determination of drugs in biological samples based merely on spiked samples are acceptable. In determining the suitability of submitted articles for publication, particular scrutiny will be placed on the degree of novelty and significance of the

7、research and the extent to which it adds to existing knowledge in pharmaceutical and biomedical analysis. In all submissions to the journal, authors must address the question of how their proposed methodology compares with previously reported methods. A substantial body of work cannot be fractionate

8、d into different shorter papers.The journal is directed towards the needs of academic, clinical, government and industrial analysis and presents a unique forum for the discussion of current developments at the interface between pharmaceutical, biochemical and clinical analysis.Submission: Authors sh

9、ould submit their manuscript online to one of the journal editors by using the Online Submission tool for the Journal of Pharmaceutical and Biomedical Analysis. To submit online authors should upload their article as a LaTeX, Microsoft （MS） Word, WordPerfect, or PostScript via the journals Author Ga

10、teway homepage at The system generates an Adobe Acrobat PDF version of the article which is used for the reviewing process. Authors, Reviewers and Editors send and receive all correspondence by e-mail and no paper correspondence is necessary.Manuscripts must be double-spaced on one side only, with a

11、t least 2.5 cm （1 inch） margins all round. All pages should be numbered and the first page must contain the following: title; names of all authors with their addresses in full. Full instructions how to use the online submission tool are available at the online submission website of the journal Peer

12、Review: All manuscripts will be assessed by two independent Reviewers. Reviews will be assessed by one independent Reviewer. Authors will be informed of the Reviewers comments and, where permission is given, of their identities. Proofs: Proofs must be returned to the Publisher within the time period

13、 specified, after which the Editors reserve the right to make any necessary corrections to a paper prior to publication. Only necessary amendments will be accepted at this stage and any changes not of a typographical nature may be charged to the Author. Reprints: Twenty-five reprints of each paper w

14、ill be sent to the corresponding author free of charge. Additional copies may be ordered on the form accompanying the proofs. General Considerations: Please write your text in good english （American or British usage is accepted, but not a mixture of these）.Language Polishing: Upon request, Elsevier

15、will direct authors to an agent who can check and improve the English of their paper （before submission）. Please contact authorsupport for further information. A number of the commonly accepted abbreviations that may be used without further definition are described in the journals list of abbreviati

16、ons. Any other terms to be abbreviated should first be defined and then followed immediately by the abbreviation in parentheses. Articles should be written in the past tense and in the impersonal style （I, we, me, us, etc. are to be avoided, except in the Acknowledgements section）. The following typ

17、es of papers will be considered for publication:Reviews: Authors wishing to submit a review should send a short synopsis to one of the editors before starting detailed work on a manuscript. The structure and presentation of a review article will normally be at the authors discretion. Reviews may be

18、relatively short, i.e. dealing with a limited subject, or longer and more general in nature. Full Length Research Papers: These papers should describe in detail original and important pieces of work in the fields covered by the Journal. Each paper should be set out as follows:Title: This should be a

19、s brief as possible consistent with clarity. Authors names should be given with full addresses. The name of the corresponding author, to whom reprints will be addressed, should be marked with an asterisk and the corresponding authors telephone number; fax number and email address should be indicated

20、. Keywords: The detailed subject index of the journal is compiled annually with the aid of keywords furnished by authors. These keywords （or key phrases） must be carefully selected to reflect the scope of the paper. General words （e.g. immunoassay, chromatography） should be avoided in favour of more

21、 specific terms （e.g. enzyme immunoassay, reversed-phase chromatography）. Normally six keywords or key phrases will be sufficient. Abstract: This should be a concise self-contained summary of the principal results of the work described, together with any essential experimental details. Introduction:

22、 This should be a concise statement of the background to the work presented, including relevant earlier work, suitably referenced. The importance of the subject and reasons for the readers presumed interest should be indicated. Experimental （or Materials and Methods）: This section should contain rea

23、sonably detailed accounts of materials and experimental procedures, and/or references to previously published methods used. Sufficient information should be provided to permit repetition of the work by other workers. When describing mixed solvents for chromatography, extraction or other purposes, th

24、e following convention must be adopted: solvent Asolvent Bsolvent C （a:b:c, v/v/v） or （a:c, w/w/w） where a:c are the proportions （by volume or weight as appropriate） of the components A, B and C, respectively. The method of preparation of buffers should be clearly expressed, with the pH value and mo

25、larity stated in parentheses, e.g. sodium acetate （pH 4.7; 0.1 M）. For mixed solvent systems, it should be clearly stated whether the pH value quoted is the pH of the original aqueous component or the apparent pH （i.e. pH*） of the mixed solvent system. Typical examples of mobile phases employed in l

26、iquid chromatography might be:acetonitrilesodium octylsulphate （10 mM）sodium acetate （pH 4.7;0.1 M） （25:25:50, v/v/v）, and acetonitrilesodium octylsulphate （10 mM）sodium acetate （0.1 M）（25:50, v/v/v ）（pH* 4.7）. Discussion of the optimisation procedure for the proposed method / assay should be given

27、in detail. Results: The important results of the work should be clearly stated and illustrated where necessary by tables and figures. The latter should be kept to the minimum consistent with clarity. In particular figures showing linear analytical response curves are generally unnecessary, and will

28、be deleted. The details of slope, intercept, standard error of slope, standard error of intercept, concentration range and number of standards are essential and they should be given in the text or tabulated. This section may also contain experimental detail such as that obtained when describing the development of new analytical procedures. It should include all relevant validat