双语教学中的生物化学词汇.docx

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双语教学中的生物化学词汇.docx

双语教学中的生物化学词汇

双语生物化学词汇

GlossaryofBiochemistryBilingually

A

Absoluteconfiguration(绝对构型)Theconfigurationoffourdifferentsubstituentgroupsaroundanasymmetriccarbonatom,inrelationtou-andi.-glyceraldehyde.

Absorption(吸收):

transportoftheproductsofdigestionfromtheintestinaltractintotheblood.

Acceptorcontrol(受体控制):

TheregulationoftherateofrespirationbytheavailabilityofADPasphosphategroupacceptor.

Accessorypigments(辅助色素):

Visiblelight-absorbingpigments(carotenoids,xanthophyll,andphycobilins藻胆素)inplantsandphotosyntheticbacteriathatcomplementchlorophyllsintrappingenergyfromsunlight.

Acidosis(酸中毒):

Ametabolicconditioninwhichthecapacityofthebodytobufferisdiminished;usuallyaccompaniedbydecreasedbloodpH.

Actin(肌动蛋白):

Aproteinmakingupthethinfilaments(细丝)ofmuscle;alsoanimportantcomponentofthecytoskeletonofmanyeukaryoticcells.

Activationenergy(ΔG*)(活化能):

Theamountofenergy(injoules)requiredtoconvertallthemoleculesin1moleofareactingsubstancefromthegroundstatetothetransitionstate.

Activator:

(活化物、激活剂)

(1)ADNA-bindingproteinthatpositivelyregulatestheexpressionofoneormoregenes;thatis,transcriptionratesincreasewhenanactivatorisboundtotheDNA.

(2)Apositivemodulatorofanallostericenzyme.

Activesite:

(活性部位)Theregionofanenzymesurfacethatbindsthesubstratemoleculeandcatalyticallytransformsit;alsoknownasthecatalyticsite.

Activetransport:

(主动运输)Energy-requiringtransportofasoluteacrossamembraneinthedirectionofincreasingconcentration.

Activity:

(活度)Thetruethermodynamicactivityorpotentialofasubstance,asdistinctfromitsmolarconcentration.

Activitycoefficient:

(活度系数)Thefactorbywhichthenumericalvalueoftheconcentrationofasolutemustbemultipliedtogiveitstruethermodynamicactivity.

Adenosine3',5'-cyclicmonophosphate:

SeecyclicAMP.

Adenosinediphosphate:

SeeADP.

Adenosinetriphosphate:

SeeATP.

Adipocyte:

(脂肪细胞)Ananimalcellspecializedforthestorageoffats(triacylglycerols).

Adiposetissue:

(脂肪组织)Connectivetissuespecializedforthestorageoflargeamountsoftriacylglycerols.

ADP(adenosinediphosphate):

Aribonucleosidediphosphateservingasphosphategroupacceptorinthecellenergycycle.

Aerobe:

(需氧生物)Anorganismthatlivesinairandusesoxygenastheterminalelectronacceptorinrespiration.

Aerobic:

Requiringoroccurringinthepresenceofoxygen.

Alcoholfermentation:

(乙醇发酵)Theanaerobicconversionofglucosetoethanolviaglycolysis.Seealsofermentation.

Aldose:

(醛糖)Asimplesugarinwhichthecarbonylcarbonatomisanaldehyde;thatis,thecarbonylcarbonisatoneendofthecarbonchain.

Alkalosis:

(碱中毒)Ametabolicconditioninwhichthecapacityofthebodytobufferisdiminished;usuallyaccompaniedbyanincreaseinbloodpH.

Allostericenzyme:

(变/别构效应)Aregulatoryenzyme,withcatalyticactivitymodulatedbythenoncovalentbindingofaspecificmetaboliteatasiteotherthantheactivesite.

Allostericprotein:

(变/别构蛋白)Aprotein(generallywithmultiplesubunits)withmultipleligand-bindingsites,suchthatligandbindingatonesiteaffectsligandbindingatanother.

Allostericsite:

(变/别构部位)Thespecificsiteonthesurfaceofanallostericenzymemoleculetowhichthemodulatororeffectormoleculeisbound.

αhelix:

(α-螺旋)Ahelicalconformationofapolypeptidechain,usuallyright-handed,withmaximalintrachainhydrogenbonding;oneofthemostcommonsecondarystructuresinproteins.

Amestest:

Asimplebacterialtestforcarcinogens,basedontheassumptionthatcarcinogensaremutagens.

Aminoacidactivation:

(氨基酸活化)ATP-dependentenzymaticesterificationofthecarboxylgroupofanaminoacidtothe3'-hydroxylgroupofitscorrespondingtRNA.

Aminoacids:

(氨基酸)anAmino-substitutedcarboxylicacids,thebuildingblocksofproteins.

Amino-terminalresidue:

(氨基末端残基)Theonlyaminoacidresidueinapolypeptidechainwithafreea-aminogroup;definestheaminoterminusofthepolypeptide.

Aminoacyl-tRNA:

(氨酰tRNA)AnaminoacylesterofatRNA.

Aminoacyl-tRNAsynthetases:

(氨酰tRNA合成酶)Enzymesthatcatalyzesynthesisofanaminoacyl-tRNAattheexpenseofATPenergy.

Aminotransferases:

(氨基转移酶)Enzymesthatcatalyzethetransferofaminogroupsfromα-aminotoα-ketoacids;alsocalledtransaminases.

Ammonotelic:

(排氨的)Excretingexcessnitrogenintheformofammonia.

Amphibolicpathway:

(双向代谢途径)Ametabolicpathwayusedinbothcatabolismandanabolism.

Amphipathic:

(双亲的)Containingbothpolarandnonpolardomains.

Ampholyte:

(两性电解质)Asubstancethatcanactaseitherabaseoranacid.

Amphoteric:

(两性的)Capableofdonatingandacceptingprotons,thusabletoserveasanacidorabase.

Anabolisim:

(合成代谢)Thephaseofintermediarymetabolismconcernedwiththeenergy-requiringbiosynthesisofcellcomponentsfromsmallerprecursors.

Anaerobe:

(厌氧生物)Anorganismthatliveswithoutoxygen.Obligateanaerobes(专性厌氧生物)diewhenexposedtooxygen.

Anaerobic:

(厌氧的)Occurringintheabsenceofairoroxygen.

Anapleroticreaction:

(回补反应)Anenzyme-catalyzedreactionthatcanreplenishthesupplyofintermediatesinthecitricacidcycle.

Angstrom(Ǻ):

(唉)Aunitoflength(10-8cm)usedtoindicatemoleculardimensions.

Anhydride:

(酸酐)Theproduct,ofthecondensationoftwocarboxylorphosphategroupsinwhichtheelementsofwaterareeliminatedtoformacompoundwiththegeneralstructureR—X—0—X—R,whereXiseithercarbonorphosphorus.

Anion-exchangeresin:

(阴离子交换树脂)Apolymericresinwithfixedcationicgroups;usedinthechromatographicseparationofanions.

Anomers:

(异头物、端基异构体)Twostereoisomersofagivensugarthatdifferonlyintheconfigurationaboutthecarbonyl(anomeric)carbonatom.

Antibiotic:

(抗生素)Oneofmanydifferentorganiccompoundsthatareformedandsecretedbyvariousspeciesofmicroorganismsandplants,aretoxictootherspecies,andpresumablyhaveadefensivefunction.

Antibody:

(抗体)Adefenseproteinsynthesizedbytheimmunesystemofvertebrates.Seealsoimmunoglobulin.

Anticodon:

(反密码子)AspecificsequenceofthreenucleotidesinatRNA,complementarytoacodonforanaminoacidinanmRNA.

Antigen:

(抗原)Amoleculecapableofelicitingthesynthesisofaspecificantibodyinvertebrates.

Antiparallel:

(反平行)Describingtwolinearpolymersthatareoppositeinpolarityororientation.

Antiport:

(反向转运)Cotransportoftwosolutesacrossamembraneinoppositedirections.

Apoenzyme:

(酶蛋白)Theproteinportionofanenzyme,exclusiveofanyorganicorinorganiccofactorsorprostheticgroupsthatmightberequiredforcatalyticactivity.

Apolipoprotein:

(脱辅基脂蛋白)Theproteincomponentofalipoprotein.

Apoprotein:

(脱辅基蛋白)Theproteinportionofaprotein,exclusiveofanyorganicorinorganiccofactorsorprostheticgroupsthatmightberequiredforactivity.

Apoptosis:

(细胞凋亡)(app'-a-toe'-sis)Programmedcelldeath,inwhichacellbringsaboutitsowndeathandlysis,signaledfromoutsideorprogrammedinitsgenes,bysystematicallydegradingitsownmacromolecules.

Arrestin:

(抑制蛋白)Afamilyofproteinsthatbindtothephosphorylatedcarboxyl-terminalregionofserpentinereceptors,preventingtheirinteractionswithGproteinsandtherebyterminatingthesignalthroughthosereceptors.

Asymmetriccarbonatom:

(不对称碳原子)Acarbonatomthatiscovalentlybondedtofourdifferentgroupsandthusmayexistintwodifferenttetrahedralconfigurations.

ATP(adenosinetriphosphate):

Aribonucleoside5'-triphosphatefunctioningasaphosphategroupdonorinthecellenergycycle;carrieschemicalenergybetweenmetabolicpathwaysbyservingasasharedintermediatecouplingendergonicandexergonicreactions.

ATPsynthase:

(ATP合酶)AnenzymecomplexthatformsATPfromADPandphosphateduringoxidativephosphorylationintheinnermitochondrialmembraneorthebacterialplasmamembrane,andduringphotophosphorylationinchloroplasts.

ATPase:

(ATP酶)AnenzymethathydrolyzesATPtoyieldADPandphosphate;usuallycoupledtosomeprocessrequiringenergy.

Attenuator:

(弱化子)AnRNAsequenceinvolvedinregulatingtheexpressionofcertaingenes;functionsasatranscriptionterminator.

Autotroph:

(自养生物)Anorganismthatcansynthesizeitsowncomplexmoleculesfromverysimplecarbonandnitrogensources,suchascarbondioxideandammonia.

Auxin:

(植物生长素)Aplantgrowthhormone.

Auxotrophicmutant(auxotroph):

(营养缺陷突变体)Amutantorganismdefectiveinthesynthesisofagivenbiomolecule,whichmustthereforebesuppliedfortheorganism'sgrowth.

Avogadro'snumber:

Thenumberofmoleculesinagrammolecularweight(amole)ofanycompound(6.02×1023).

B

Back-mutation:

(回复突变)Amutationthatcausesamutantgenetoregainitswild-typebasesequence.

Bacteriophage(phage):

(噬菌体)Aviruscapableofreplicatinginabacterialcell.

Basalmetabolicrate:

(基础代谢率)Therateofoxygenconsumptionbyananimal'sbodyatcompleterest,longafterameal.

Basepair:

(碱基对)Twonucleotidesinnucleicacidchainsthatarepairedbyhydrogenbondingoftheirbases;forexample,AwithTorU,andGwithC.

βconformation:

(β构象)、Anextended,zigzagarrangementofapolypeptidechain;acommonsecondarystructureinproteins.

βoxidation:

(β氧化)Oxidativedegradationoffattyacidsintoacetyl-CoAbysuccessiveoxidationsattheβ-carbonatom.

β-turn:

(β转角)Atypeofsecondarystructureinpolypeptidesconsistingoffouraminoacidresiduesarrangedinatightturnsothatthepolypeptideturnsbackonitself.

Bilayer:

(双分子层)Adoublelayeroforientedamphipathiclipidmolecules,formingthebasicstructureofbiologicalmembranes.Thehydrocarbontailsfaceinwardtoformacontinuousnonpolarphase.

Bilesalts:

(胆酸盐)Amphipathicsteroidderivativeswithdetergentproperties,participatingindigestionandabsorptionoflipids.

Binding

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