IgG Food Intolerance TestsWhat does the science say.docx
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IgGFoodIntoleranceTestsWhatdoesthesciencesay
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IgGFoodIntoleranceTests:
Whatdoesthesciencesay?
Postedby ScottGavura onFebruary2,2012 43Comments
Ispendalotoftimeasapharmacistdiscussingsideeffectsandallergiestodrugs.Foryourownsafety,Iwon’trecommendordispenseadruguntilIknowyourallergystatus.Idon’tlimitthehistorytodrugs—Iwanttoknowanythingyou’reallergicto,beitenvironmental,food,insects,oranythingelse.Allergiescancreatetruetherapeuticchallenges:
Wecan’tdismissanyallergyclaim,butasI’vebloggedbefore,there’sabiggapbetween whatmanyperceiveasanallergy andwhatisclinicallyconsideredatrueallergy.Myconcernisnotonlyavoidingtheharmofanallergicreaction,butalsoavoidingthepotentialconsequencesfromselectingasuboptimaltherapythatmayinfactbeappropriate.Youmayneedaspecificdrugsomeday,so Iencouragepatientstodiscussvaguedrugallergieswiththeirphysician,andrequestallergisttestingasrequired.
Foodallergiescanbeasrealasdrugallergies,andarearguablymuchhardertoprevent.Wecanusuallycontrolwhenwegetpenicillin.Butwhataboutpeanuts,eggs,ormilk,allofwhichcanalsocauselife-threateninganaphylaxis?
Foodallergiesseemstobegrowing:
notonlyanaphylaxis,but morepeoplebelievetheyhavesomesortofallergytofood. Allergyissometimesconfusedwiththeterm“intolerance”,whichseemsmorecommon,possiblyastheavailabilityof“foodintolerancetesting”grows.Foodintolerancetestingandscreeningisparticularlypopularamongalternativepractitioners.Testingcantakedifferentforms,butgenerallytheconsumerisscreenedagainsthundredsoffoodproductsandfoodadditives.Theyarethenprovidedwithalistoffoodstheyare“intolerant”to.I’vespokenwithconsumerswhoarestrugglingtooverhaultheirdiet,havingbeenadvisedthattheyareactuallyintoleranttomanyoftheirfavouritefoods.Thesereportsaretakenseriouslybypatientswhobelievethatthey’llfeelbetteriftheyeliminatetheseproducts.Inthepharmacy,I’vebeenaskedtoverifytheabsenceoftraceamountsofdifferentfillers inmedicationsbecauseofaperceivedintolerance. Childrenmaybetested,too,andparentsmaybegivenalonglistoffoodstheyaretoldtheirchildisintolerantof.I’veseentheeffectsinthecommunity,too.Thinkgoing“peanutfree”istough?
Apublicschoolinmyareasenthomealistofforbiddenfoodproducts:
dairy,eggs,bananas,treenuts,peanuts,soy,sesame,flaxseed,kiwi,chicken,andbacon.Werethesealltrueallergies?
It’snotdisclosed.Anaphylacticornot,theparentshadinformedtheschool,andtheschoolhadbannedthefoodproduct.
Butcanasimplebloodtestactuallyidentifyandeliminatefoodintolerance?
That’sthequestionIwantedtoanswer.
Whenitcomestofoodintolerancetesting,bloodtestsarejustthestart.Othermethodsusedinclude vegatesting, the K-Test, hairtesting,and appliedkinesiology.Butthebloodtestsareenjoyingnewpopularity—andevenpharmaciesarenowactively promotingthesetests:
Youmightlovefood,butsomefoodmightnotloveyou
TheHEMOCODEFoodIntoleranceSystemcanunlockyourhiddenfoodsensitivities
SpeakwithyourRexallPharmacisttodaytolearnaboutapainlessbloodtestthatcanidentifyover250commonfoodsthatmaybecausingyouunpleasantsymptomssuchaschronicfatigue,migraines,backpain,fibromyalgia,psoriasis,acne,diarrheaandconstipation.
There’sa shortvideo(above) thatisveryillustrative.Narratedbyapharmacist,itdescribesthatasimplefingertipbloodtestisusedtoscreenbloodagainst250items.Testresultsarethenreviewedby“naturopathicmedicalprofessionals”whowilldescribethefoodsandotherproductsthatyouareintolerantto,andyourdegreeofintolerance.You’realsoadvised:
Yourpersonalizedresultsalsoincluderecommendedvitaminsandsupplementsthatareuniquelysuitedtothecustomer,basedonthefoodsthataresuggestedtobeeliminatedfromyourdiet,whicharethemselves,uniquelypersonal.
Sothe $450bloodtest,includesdietarychangerecommendationsaswellasvitaminandsupplementrecommendation.Thevendor explainsitasfollows:
Byaddingpersonalizedvitaminandsupplementrecommendations,theHemocodeSystemwillhelpconsumersmovetowardsoptimalnutritionastheyworktoeliminateoffendingfoodsfromtheirdiets.Nootherfoodintoleranceprogramoffersthistypeofseamlesslydelivered,highlycustomizedsolution.Inadditiontodeliveringameaningfulwellnessbenefittotheircustomers,theinclusionofdietarysupplementrecommendationsaspartofHemocodecreatesanopportunityforretailerstorecognize:
accretiverevenuefromHemocodeSystemsales;incrementalgrowthintheircorevitaminprogramandanenhancementoftheirmarketdifferentiation.
Thistestingisalso positionedasaweightlossplan:
WouldIbeabletoloseweightwithHEMOCODE?
Yourchancesofpermanentsuccessareexcellent:
HEMOCODE(TM)worksdifferentlythanotherconventionaldietsandrulesouttheyoyo-effect.
IsHEMOCODEamiraclediet?
Itisnotamiraclediet,butascientificallybaseddietmodification.UnlockingyourHEMOCODE(TM)getstotherootofyourproblem.Foodintolerancescanbethecauseofaweightproblemandinhibitthesuccessoflosingweightwithconventionaldiets.TheHEMOCODE(TM)testlooksatfoodsonaone-by-onebasisforindividualintolerances.
Hemocodeisjustoneofseveralbloodteststhat’smarketed.There’salsothe YorkTest intheUnitedKingdomand alsoCanada:
Foodintoleranceisallabouthowyourbodysimmunesystemthebodysnaturaldefenceagainstforeignsubstances,suchaspoisonsandharmfulbacteriareactstospecificfoods. [sic]
Foodintolerancesarebelievedtoarisewhencertain,incompletelydigestedfoodparticlesenteryourbloodstreamandaretreatedasforeignsubstances.Thisresultsinyourimmunesystemproducingtailor-madeantibodies(IgG),whichattackthefoodinquestion.Someresearchersbelievethisinflammatoryresponseinthebodycanincreasecertainsymptoms.FoodintolerancehasbeenassociatedwithIrritableBowelSyndrome(IBS),bloating,tiredness,constipation,diarrhea,cramping,eczema,headachesandmigraines.
Sojustwhatistheevidencesupportingtheuseoffoodintolerancetests?
TestingPrinciples
Diagnostictestscanbeaspseudoscientificastreatments.Toevaluate,weaskthefollowing:
∙Analyticvalidity:
Howreliableisthetesting?
Thisincludeswithin-laboratoryandbetween-laboratoryprecision.
∙Clinicalvalidity:
Howconsistentlyandaccuratelydoesthetestdetectanobjectively-measuredclinicalstatus?
Thetestshouldbebothsensitive(few falsenegatives)andspecific(fewfalsepositives).Patientsinthesamecircumstancesshouldconsistentlyhavethesametestresults.
∙Clinicalutility:
Whatisthenaturalhistoryofthedisorder?
Willtheuseofthetestmakeanydifferenceintheoutcome?
Interventionstakenshouldbeevaluatedandcomparedagainstnotesting.
∙Ethical,legal,orsocialimplications :
Whatarethepotentialpatientconsequencesoftheuseofthetest,anditsresults?
Whatiftheresultsareerroneous?
Itallboilsdowntoasinglequestionthatmustbesatisfactorilyansweredbeforeweproceedwithtesting:
Howhasthistestbeenvalidated?
What’saFoodIntoleranceBloodTestActuallyTesting?
Hemocode isanIgGbloodtest,accordingtothemanufacturer(textnowremoved;cachedversion here):
TheHemocodeSystemisafingerpricktestthatidentifiesspecificimmunesystem-basedfoodintolerances.
Everythingweeatcanelicitapositiveornegativereactioninthebody.Ifyouareintoleranttoacertainfoodandyoucontinuetoeatit,yourbodywillmountaninflammatoryreactionwhichmaymanifestinavarietyoflifestyle-affectingconditionssuchasheadaches,chronicpain,digestivedisordersandmanyotherissues
TheHemocodefoodintolerancetestisastatisticallyproven,doctorandpharmacistrecommendedIgG-relatedtestthatdetermineswhichfoodsarecausingnegativereactions.
TheYorkTestisalsoanIgGtest.ThereisnopublishedinformationintheliteraturethatdescribeseithertheHemocodeortheYorktest,ortheiranalyticvalidityforanyoftheproductstestedfor.
UnderstandingIgE,allergies,andwhatIgGmeans
Foodallergiesarereactiontofoodproteins.TheymaybecategorizedasimmunoglobulinE(IgE)–mediated(immediate)reactions,non–IgE-mediated(delayed)hypersensitivityreactions,andmixedreactions.IgE-mediatedreactionsaretheonesweworryaboutwhenwehearabouta“foodallergy”:
flushing,itchyskin,wheezing,vomiting,throatswelling,andevenanaphylaxis.Thesereactionscanoccurimmediatelyfollowingexposure,andaretheconsequenceoftheinteractionofallergenswithIgElocatedonmastcells.Theinteractioncausesthereleaseofinflammatorychemicalslikehistamineandleucotriene,triggeringthetheallergicresponsewhichistypicallyskinrelated(itchiness,swellingandrash) butmaybeanaphylacticaswell.
Notallreactionsfollowthiscascade.Non-IgE-mediatedallergicreactionscancauselocalized(e.g.,contactdermatitis)orgeneralizedreactions,whichareusuallygastrointestinalordermatologicalinnature.Celiacdiseaseisanon-IgErelatedallergicreaction.Finally,someallergicdisordersarebothIgEandnon-IgEmediated,suchasatopicdermatitis(eczema).
BeyondtheIgEmediatedreactions,thereareanumberofpossiblereactionstofood,whichmaybetermed“foodintolerances”.Notimmune-systembased,they’remorecommonthanallergies.Theyincludeconditionslikelactoseintoleran