IgG Food Intolerance TestsWhat does the science say.docx

IgG Food Intolerance TestsWhat does the science say.docx

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IgGFoodIntoleranceTestsWhatdoesthesciencesay

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//www.sciencebasedmedicine.org/igg-food-intolerance-tests-what-does-the-science-say/

IgGFoodIntoleranceTests:

Whatdoesthesciencesay?

Postedby ScottGavura onFebruary2,2012 43Comments

Ispendalotoftimeasapharmacistdiscussingsideeffectsandallergiestodrugs.Foryourownsafety,Iwon’trecommendordispenseadruguntilIknowyourallergystatus.Idon’tlimitthehistorytodrugs—Iwanttoknowanythingyou’reallergicto,beitenvironmental,food,insects,oranythingelse.Allergiescancreatetruetherapeuticchallenges:

Wecan’tdismissanyallergyclaim,butasI’vebloggedbefore,there’sabiggapbetween whatmanyperceiveasanallergy andwhatisclinicallyconsideredatrueallergy.Myconcernisnotonlyavoidingtheharmofanallergicreaction,butalsoavoidingthepotentialconsequencesfromselectingasuboptimaltherapythatmayinfactbeappropriate.Youmayneedaspecificdrugsomeday,so Iencouragepatientstodiscussvaguedrugallergieswiththeirphysician,andrequestallergisttestingasrequired.

Foodallergiescanbeasrealasdrugallergies,andarearguablymuchhardertoprevent.Wecanusuallycontrolwhenwegetpenicillin.Butwhataboutpeanuts,eggs,ormilk,allofwhichcanalsocauselife-threateninganaphylaxis?

 Foodallergiesseemstobegrowing:

notonlyanaphylaxis,but morepeoplebelievetheyhavesomesortofallergytofood. Allergyissometimesconfusedwiththeterm“intolerance”,whichseemsmorecommon,possiblyastheavailabilityof“foodintolerancetesting”grows.Foodintolerancetestingandscreeningisparticularlypopularamongalternativepractitioners.Testingcantakedifferentforms,butgenerallytheconsumerisscreenedagainsthundredsoffoodproductsandfoodadditives.Theyarethenprovidedwithalistoffoodstheyare“intolerant”to.I’vespokenwithconsumerswhoarestrugglingtooverhaultheirdiet,havingbeenadvisedthattheyareactuallyintoleranttomanyoftheirfavouritefoods.Thesereportsaretakenseriouslybypatientswhobelievethatthey’llfeelbetteriftheyeliminatetheseproducts.Inthepharmacy,I’vebeenaskedtoverifytheabsenceoftraceamountsofdifferentfillers inmedicationsbecauseofaperceivedintolerance. Childrenmaybetested,too,andparentsmaybegivenalonglistoffoodstheyaretoldtheirchildisintolerantof.I’veseentheeffectsinthecommunity,too.Thinkgoing“peanutfree”istough?

Apublicschoolinmyareasenthomealistofforbiddenfoodproducts:

dairy,eggs,bananas,treenuts,peanuts,soy,sesame,flaxseed,kiwi,chicken,andbacon.Werethesealltrueallergies?

It’snotdisclosed.Anaphylacticornot,theparentshadinformedtheschool,andtheschoolhadbannedthefoodproduct.

Butcanasimplebloodtestactuallyidentifyandeliminatefoodintolerance?

That’sthequestionIwantedtoanswer.

Whenitcomestofoodintolerancetesting,bloodtestsarejustthestart.Othermethodsusedinclude vegatesting, the K-Test, hairtesting,and  appliedkinesiology.Butthebloodtestsareenjoyingnewpopularity—andevenpharmaciesarenowactively promotingthesetests:

Youmightlovefood,butsomefoodmightnotloveyou

TheHEMOCODEFoodIntoleranceSystemcanunlockyourhiddenfoodsensitivities

SpeakwithyourRexallPharmacisttodaytolearnaboutapainlessbloodtestthatcanidentifyover250commonfoodsthatmaybecausingyouunpleasantsymptomssuchaschronicfatigue,migraines,backpain,fibromyalgia,psoriasis,acne,diarrheaandconstipation.

There’sa shortvideo（above） thatisveryillustrative.Narratedbyapharmacist,itdescribesthatasimplefingertipbloodtestisusedtoscreenbloodagainst250items.Testresultsarethenreviewedby“naturopathicmedicalprofessionals”whowilldescribethefoodsandotherproductsthatyouareintolerantto,andyourdegreeofintolerance.You’realsoadvised:

Yourpersonalizedresultsalsoincluderecommendedvitaminsandsupplementsthatareuniquelysuitedtothecustomer,basedonthefoodsthataresuggestedtobeeliminatedfromyourdiet,whicharethemselves,uniquelypersonal.

Sothe $450bloodtest,includesdietarychangerecommendationsaswellasvitaminandsupplementrecommendation.Thevendor explainsitasfollows:

Byaddingpersonalizedvitaminandsupplementrecommendations,theHemocodeSystemwillhelpconsumersmovetowardsoptimalnutritionastheyworktoeliminateoffendingfoodsfromtheirdiets.Nootherfoodintoleranceprogramoffersthistypeofseamlesslydelivered,highlycustomizedsolution.Inadditiontodeliveringameaningfulwellnessbenefittotheircustomers,theinclusionofdietarysupplementrecommendationsaspartofHemocodecreatesanopportunityforretailerstorecognize:

accretiverevenuefromHemocodeSystemsales;incrementalgrowthintheircorevitaminprogramandanenhancementoftheirmarketdifferentiation.

Thistestingisalso positionedasaweightlossplan:

WouldIbeabletoloseweightwithHEMOCODE?

Yourchancesofpermanentsuccessareexcellent:

HEMOCODE（TM）worksdifferentlythanotherconventionaldietsandrulesouttheyoyo-effect.

IsHEMOCODEamiraclediet?

Itisnotamiraclediet,butascientificallybaseddietmodification.UnlockingyourHEMOCODE（TM）getstotherootofyourproblem.Foodintolerancescanbethecauseofaweightproblemandinhibitthesuccessoflosingweightwithconventionaldiets.TheHEMOCODE（TM）testlooksatfoodsonaone-by-onebasisforindividualintolerances.

Hemocodeisjustoneofseveralbloodteststhat’smarketed.There’salsothe YorkTest intheUnitedKingdomand alsoCanada:

Foodintoleranceisallabouthowyourbodysimmunesystemthebodysnaturaldefenceagainstforeignsubstances,suchaspoisonsandharmfulbacteriareactstospecificfoods. [sic]

Foodintolerancesarebelievedtoarisewhencertain,incompletelydigestedfoodparticlesenteryourbloodstreamandaretreatedasforeignsubstances.Thisresultsinyourimmunesystemproducingtailor-madeantibodies（IgG）,whichattackthefoodinquestion.Someresearchersbelievethisinflammatoryresponseinthebodycanincreasecertainsymptoms.FoodintolerancehasbeenassociatedwithIrritableBowelSyndrome（IBS）,bloating,tiredness,constipation,diarrhea,cramping,eczema,headachesandmigraines.

Sojustwhatistheevidencesupportingtheuseoffoodintolerancetests?

TestingPrinciples

Diagnostictestscanbeaspseudoscientificastreatments.Toevaluate,weaskthefollowing:

∙Analyticvalidity:

 Howreliableisthetesting?

Thisincludeswithin-laboratoryandbetween-laboratoryprecision.

∙Clinicalvalidity:

 Howconsistentlyandaccuratelydoesthetestdetectanobjectively-measuredclinicalstatus?

Thetestshouldbebothsensitive（few falsenegatives）andspecific（fewfalsepositives）.Patientsinthesamecircumstancesshouldconsistentlyhavethesametestresults.

∙Clinicalutility:

 Whatisthenaturalhistoryofthedisorder?

Willtheuseofthetestmakeanydifferenceintheoutcome?

Interventionstakenshouldbeevaluatedandcomparedagainstnotesting.

∙Ethical,legal,orsocialimplications :

Whatarethepotentialpatientconsequencesoftheuseofthetest,anditsresults?

Whatiftheresultsareerroneous?

Itallboilsdowntoasinglequestionthatmustbesatisfactorilyansweredbeforeweproceedwithtesting:

 Howhasthistestbeenvalidated?

What’saFoodIntoleranceBloodTestActuallyTesting?

Hemocode isanIgGbloodtest,accordingtothemanufacturer（textnowremoved;cachedversion here）:

TheHemocodeSystemisafingerpricktestthatidentifiesspecificimmunesystem-basedfoodintolerances.

Everythingweeatcanelicitapositiveornegativereactioninthebody.Ifyouareintoleranttoacertainfoodandyoucontinuetoeatit,yourbodywillmountaninflammatoryreactionwhichmaymanifestinavarietyoflifestyle-affectingconditionssuchasheadaches,chronicpain,digestivedisordersandmanyotherissues

TheHemocodefoodintolerancetestisastatisticallyproven,doctorandpharmacistrecommendedIgG-relatedtestthatdetermineswhichfoodsarecausingnegativereactions.

TheYorkTestisalsoanIgGtest.ThereisnopublishedinformationintheliteraturethatdescribeseithertheHemocodeortheYorktest,ortheiranalyticvalidityforanyoftheproductstestedfor.

UnderstandingIgE,allergies,andwhatIgGmeans

Foodallergiesarereactiontofoodproteins.TheymaybecategorizedasimmunoglobulinE（IgE）–mediated（immediate）reactions,non–IgE-mediated（delayed）hypersensitivityreactions,andmixedreactions.IgE-mediatedreactionsaretheonesweworryaboutwhenwehearabouta“foodallergy”:

flushing,itchyskin,wheezing,vomiting,throatswelling,andevenanaphylaxis.Thesereactionscanoccurimmediatelyfollowingexposure,andaretheconsequenceoftheinteractionofallergenswithIgElocatedonmastcells.Theinteractioncausesthereleaseofinflammatorychemicalslikehistamineandleucotriene,triggeringthetheallergicresponsewhichistypicallyskinrelated（itchiness,swellingandrash） butmaybeanaphylacticaswell.

Notallreactionsfollowthiscascade.Non-IgE-mediatedallergicreactionscancauselocalized（e.g.,contactdermatitis）orgeneralizedreactions,whichareusuallygastrointestinalordermatologicalinnature.Celiacdiseaseisanon-IgErelatedallergicreaction.Finally,someallergicdisordersarebothIgEandnon-IgEmediated,suchasatopicdermatitis（eczema）.

BeyondtheIgEmediatedreactions,thereareanumberofpossiblereactionstofood,whichmaybetermed“foodintolerances”.Notimmune-systembased,they’remorecommonthanallergies.Theyincludeconditionslikelactoseintoleran