一些常用的SCI论文句式Word格式.doc

一些常用的SCI论文句式Word格式.doc

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1．ThemechanismsgoverningthehomeostasisofmemoryTcellshavebeenanareaofintenseinvestigation.

2．Extensiveworkhasbeendoneintheareaofcytokinesignaling.

3．Notunexpectedly,thenewest‘lineage’ofhelperTcells,TH-17cells,alsoreceivedagreatdealofattentionattheRingbergmeeting.

4.WhiletheinteractionsofDCwithnaiveTcellswithinLNhavebeenanalysedindetail,…

5.WhileinteractionsofDCwithnaiveTcellsinLNhavebeenextensivelyexaminedby2P-IVM,

6.Althoughthesignalsthatcontrolneutrophilmigrationfromthebloodtositesofinfectionhavebeenwellcharacterized,littleisknownabouttheirmigrationpatternswithinlymphnodesorthestrategiesthatneutrophilsusetofindtheirlocalsitesofaction.

不像B，which…，A…

1.UnlikenaiveTcells,whichsurvivelargelyininterphase,memoryTcellspersistundernormalconditionswithaslowbutconstantturnover.

像…一样

1．AswithnaiveTcells,memoryTcellsarealsocapableofundergoingmorerapidcelldivisionunderlymphopenicconditions,knownasacute

homeostaticproliferation.

…已有共识

1．Thereisnowageneralconsensusthattwomembersofthecommonγchaincytokinefamily,namelyIL-7andIL-15,controlthehomeostasisofCD8+

memorycells

…仍不清楚

1.However,thefactorsthatgovernthehomeostasisofCD4+memorycellshaveyettobefullydefined.

2.Althoughmoleculardetailsoftheprocessarepoorlyunderstood.

3.AlthoughwhythissubsetofTcellsisuniquelysensitivetoIL-2iscurrentlyunclear.

4.experimentsdirectlyinterrogatingthephysiologicalrequirements

forDC-producedIL-2haveyettobepublished.

5.AmongthequestionsthatremaintoberesolvedarehowIL-2mayplaybothsupportiveandrestrictiverolesinthesametransgenicOT-1CD8+Tcells.

6.ThecauseofthisdiseasehasbeenelusivebecausetheSAPgeneisnotaffectedinXLP2patients.

7．ThemainsourceofIL-17atthelocalsiteofinflammationstillremainsunknown.

8.WhethersuchamechanismisrelevanttoCD4+Thelpercellsremainsanopenissue.

9.WhetherthefailuretosilenceTRAILsynthesisuponrechallengeexplainsthisexampleofAICDremainstobeinvestigated.

10.WhetherthereceivingcellmustmakecontactwiththeproducingcellorwhetherthereisaroleforsolubleIL-15/IL-15RαcomplexesinCD8+memoryTcellhomeostasisisnotclear.

11.ButthequestionofwhethertheyneedtonicsignalsviatheirTCRisstillopen.

12.ExactlywhatCD4+TcellsprovidetomaintainCD8+Tcellmemoryremainsamystery.

13．LargequestionsremainastohowchemokinesignalingregulatesorisregulatedtocoordinatethecomplexinvivodynamicsoftheTlymphocytes。

14.However,whathasnotbeendelineatedistheresponseofeffectorTcellsatnonlymphoidtissuesiteswhentheyreencounterAg.

15.ThepreciseroleofIL-2intheregulationofCD8TcellresponsestoforeignAginvivohoweverremainsenigmatic.

16．OurunderstandingofthedevelopmentalcontrolofV（D）Jrecombinationontheonehand,andthatofcellproliferation,death,andsurvivalduringdifferentiationontheother,isstillfragmentary.

…已经得到公认

1．Itiswellacceptedthattwocytokines,namelyIL-7andIL-15,areinvolvedinmaintainingthenumbersofCD8memorycellsinvivo（145–147）.

与…相似

1．Inaddition,thereisahigh-affinityreceptorforIL-15,referredtoasIL-15Rα,anditwasthought,inanalogywiththeIL-2R,thatathree-chaincomplex,αβγ,wasthereceptorforIL-15onNKcellsandmemoryCD8+Tcells.

仍存在争议

1．Itwasclearthatthereisnoshortageofcontroversy.

可以肯定地说

1．Itissafetosay,infact,thatthereisalongwaytogobeforethefieldfullyunderstandstheprocessofeffectorandmemorycelldifferentiation,therelationshipsamongthesepost-activationcellfatesandtheextenttowhichanygivenTcelladoptsafixedversusaflexiblefunctionalprogramafterantigenactivation.

2.Thereisnodoubtimmunologicalresearchhasbeenboostedbythe

recentapplicationof2P-IVM

依赖、需要

1．Ag-specificmemoryCD8+cells,ontheotherhand,arelessdependentonIL-15,relyingmoreonIL-7,butstillrequireIL-15forbasalhomeostaticproliferationandlong-termmaintenance

2．Furthermore,robustCD8recallresponsesappeartobeparticularlyreliantonCD8costimulationvia4-1BB.

A与B之间的差异

1．ThediscrepancyinthehomeostaticrequirementsforAg-specificmemoryversusMPcellsappearsevengreaterforCD4+thanCD8+cells.

与…一致,相符

1．Consistentwiththisnotion,recentstudieshaveshownthatIL-7isessentialforthesurvivalandbasalhomeostaticturnoverofAg-specificCD4+memorycells.

2.SimilarlybroadexpressionofIL-2andIL-15receptorsdonotcoincidewellwiththehighlyrestrictedrolest