美国药典色谱柱型号对照之欧阳与创编.docx

1、美国药典色谱柱型号对照之欧阳与创编美国药典色谱柱型号对照 时间：2021.03.08创作：欧阳与下面是USP规定的编号所对应的色谱柱类型。L1：十八烷基键合多孔硅胶或无机氧化物微粒固定相，简称ODS柱L2：3050mm表面多孔薄壳型键合十八烷基固定相，简称C18柱L3：多孔硅胶微粒，即一般的硅胶柱L4：3050mm表面多孔薄壳型硅胶柱L5：3050mm表面多孔薄壳型氧化铝柱L6：3050mm实心微球表面包覆磺化碳氟聚合物，强阳离子交换柱L7：全多孔硅胶微粒键合C8官能团固定相，简称C8柱L8：全多孔硅胶微粒键合非交联NH2固定相，简称NH2柱L9：强酸性阳离子交换基团键合全多孔不规则形硅胶固定

2、相，即SCX柱L10：多孔硅胶微球键合氰基固定相（CN），简称CN柱L11：键合苯基多孔硅胶微球固定相，简称苯基柱L12：无孔微球键合季胺功能团的强阴离子交换柱L13：三乙基硅烷化学键合全多孔硅胶微球固定相（C1），简称C1柱L14：10mm硅胶化学键合强碱性季铵盐阴离子交换固定相，简称SAX柱L15：已基硅烷化学键合全多孔硅胶微球固定相，简称C6柱L16：二甲基硅烷化学键合全多孔硅胶微粒固定相 C2柱L17：氢型磺化交联苯乙烯-二乙烯基苯共聚物,强阳离子交换柱L18：310mm全多孔硅胶化学键合胺基（NH2）和氰基（CN）柱L19：钙型磺化交联苯乙烯二乙烯基苯共聚物，强阳离子交换柱L20：二

3、羟基丙烷基化学键合多孔硅胶微球固定相（Diol），简称二醇基柱L21：刚性苯乙烯二乙烯基苯共聚物微球填料柱L22：带有磺酸基团的多孔苯乙烯阳离子交换柱L23：带有季胺基团的聚甲基丙烯酸甲酯或聚丙烯酸酯多孔离子交换柱L24：表面含有大量羟基的半刚性聚乙烯醇亲水凝胶柱L25：聚甲基丙烯酸酯树脂交联羟基醚（表面含有残余羧基功能团）树脂。能分离分子量1005000MW范围的水溶性中性、阳离子型及阴离子型聚合物（用聚氧乙烯测定）的固定相L26：丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27：3050mm的全多孔硅胶微粒L28：多功能载体，100的高纯硅胶加以氨基键合以及C8反相键合的官能团L29:

4、氧化铝,反相键合,含碳量低,氧化铝基聚丁二稀小球,5mm，孔径80L30:全多孔硅胶键合乙基硅烷固定相L31:季胺基改性孔径2000的交联苯乙烯和二乙烯基苯(55%)强阴离子交换树脂L32: L-脯氨酸铜配合物共价键合于不规则形硅胶微粒的配位体的交换手性色谱填料L33:能够分离分子量400040000MW范围蛋白质分子的球形硅胶固定相, pH稳定性好L34：铅型磺化交联苯乙烯二乙烯基苯共聚物强阳离子交换树脂，9mm球形L35：锆稳定的硅胶微球键合二醇基亲水分子单层固定相，孔径150L36:5mm胺丙基硅胶键合L-苯基氨基乙酸3,5二硝基苯甲酰L37：适合分离分子量200040000MW的聚甲基

5、丙烯酸酯凝胶L38：水溶性甲基丙烯酸酯基质SEC色谱柱L39：亲水全多孔聚羟基甲基丙烯酸酯色谱柱L40：Tris 3,5二甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球L41：球形硅胶表面固定1酸糖蛋白固定相L42: C8和C18硅烷化学键合多孔硅胶固定相L43:硅胶微球键合五氟代苯基固定相L44:多功能固定相,60 高纯硅胶基质键合磺酸阳离子交换功能团和C8反相功能团L45: -环糊精键合多孔硅胶微球L46:季胺基改性苯乙烯-二乙烯基苯聚合物微球L1 Octadecyl silane chemically bonded to porous silica or ceramic.L1 十八烷基键合硅烷

6、化学键合于多孔硅胶或陶瓷微粒，3-10u。L2 Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core, 30 to 50 m in diameter.L2 十八烷基键合硅烷化学键合于表面空隙率一定的键合在紧密球核上的硅胶，粒径30-50u。L3 Porous silica particles, 5 to 10 m in diameter.L3 多孔硅胶颗粒，粒径5-10u。L4 Silica

7、gel of controlled surface porosity bonded to a solid spherical core,30 to 50 m in diameter.L4 表面空隙率一定的硅胶键合于紧密球核上，粒径30-50u。L5 Alumina of controlled surface porosity bonded to a solid spherical core,30 to 50 m in diameter.L5 表面空隙率一定的氧化铝键合于紧密球核上，粒径30-50u。L6 Strong cation-exchange packing: sulfonated fl

8、uorocarbon polymer coated on a solid spherical core, 30 to 50 m in diameter.L6 强阳离子交换填料：磺化氟代烃聚合物涂渍于紧密球核上，粒径30-50u。L7 Octyl silane chemically bonded to totally porous silica particles, 1.5 to 10 m in diameter.L7 辛基硅烷化学键合于完全多孔硅胶担体，粒径10u。L8 An essentially monomolecular layer of aminopropyl-silane chemi

9、cally bondedto totally porous silica gel support, 3 to 10 m in diameter.L8 氨丙基硅烷单分子层化学键合于完全多孔硅胶担体，粒径10u。L9 Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic ation-exchange coating, 3 to 10 m in diameter.L9 10u不规则的完全多孔硅胶具有化学键合的强酸性阳离子交换涂层。L10 Nitrile groups

10、chemically bonded to porous silica particles, 3 to 10 m in diameter.L10 氰基团化学键合于多孔微粒硅，粒径3-10u。L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 m in diameter.L11 苯基化学键合于多孔微粒硅，粒径3-10u。L12 Strong anion-exchange packing made by chemically bonding a quaternary amine to a solid si

11、lica spherical core, 30 to 50 m in diameterL12 由四元胺化学键合于精密硅球核形成的强阴离子交换填料，粒径30-50u。L13 Trimethylsilane chemically bonded to porous silica particles,3 to 10 m in diameter.L13 三甲基硅烷化学键合于完全多孔硅胶，粒径3-10u。L14 Silica gel having a chemically bonded, strongly basic quaternary ammonium anion-exchange coating,

12、5 to 10 m in diameter.L14 具有强碱性四元胺阴离子交换涂层的10u硅胶化学键合相。L15 Hexyl silane chemically bonded to totally porous silica particles,3 to 10 m in diameter.L15 己基硅烷化学键合于完全多孔性微粒硅，粒径3-10u。L16 Dimethyl silane chemically bonded to totally porous silica particles, 5 to 10 m in diameter.L16 二甲基硅烷化学键合于完全多孔性微粒硅，粒径3-10

13、u。L17 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the hydrogen form, 7 to 11 m in diameter.L17 由磺化的苯乙烯-二乙烯基苯交连共聚物组成的氢型阳离子交换树脂，粒径7-11u。L18 Amino and cyano groups chemically bonded to porous silica particles,3 to 10 m in diameter.L18 氨基和氰基化学键合

14、于多孔微粒硅，粒径3-10u。L19 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the calcium form, 9 m in diameter.L19 由磺化的苯乙烯-二乙烯基苯交连共聚物组成的钙型阳离子交换树脂，粒径7-11u。L20 Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 m in diameter.L20 二

15、甲氧基丙烷基化学键合于多孔硅胶微粒，粒径5-10u。L21 A rigid, spherical styrene-divinylbenzene copolymer, 5 to 10 m in diameter.L21 刚性球形苯乙烯-二乙烯基苯共聚物，粒径5-10u。L22 A cation exchange resin made of porous polystyrene gel with sulfonic acid groups, about 10 m in size.L22 由多孔聚苯乙烯凝胶和磺酸基组成的阳离子交换树脂，粒径约为10u。L23 An anion exchange res

16、in made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups, about 10 m in size.L23 由多孔聚甲基丙烯酸酯或聚丙烯酸酯凝胶及四元胺基组成的阴离子交换树脂，粒径约为10u。L24 A semi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface, 32 to 63 m in diameter.L24 由乙烯基聚

17、合物和基质表面的无数羟基组成的半刚性亲水硅胶，粒径32u-63u。L25 Packing having the capacity to separate compounds with a MW range from 100 to 5000 daltons (as determined by polyethylene oxide), applied to neutral, anionic, and cationic water-soluble polymers. A polymethacrylate resin base,crosslinked with poly-hydroxylated et

18、her (surface contained some residual carboxyl functional groups) was found suitable.L25 能分离MW从100到5000Da化合物的填料（取决于聚环氧乙烷），应用于中性、阴离子和阳离子的水溶性聚合物。聚甲基丙烯酸酯作为树脂基质，与聚羟基化醚（表面含一些残余羧基官能团）进行交连。L26 Butyl silane chemically bonded to totally porous silica particles, 5 to 10 m in diameter.L27 Porous silica particle

19、s, 30 to 50 m in diameter.L28 A multifunctional support, which consists of a high purity, 100 , spherical silica substrate that has been bonded with anionic (amine) functionality in addition to a conventional reversed phase C8 functionality.L29 Gamma alumina, reversed phase, low carbon percentage by

20、 weight, alumina-based polybutadiene spherical particles, 5 m diameter with a pore diameter of 80 .L30 Ethyl silane chemically bonded to a totally porous silica particle, 3 to 10 m in diameter.L31 A strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5 m ma

21、croporous particles having a pore size of 2000 and consisting of ethylvinylbenzene cross-linked with 55 % divinyl benzene.L32 A chiral ligand-exchange packing- L-proline copper complex covalently bonded to irregularly shaped silica particles, 5 to 10 m in diameter.L33 Packing having the capacity to

22、separate proteins of 4,000 to 400,000 daltons. It is spherical, silica-based and processed to provide pH stability.L34 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene copolymer in the lead form, about 9 m in diameter.L35 A zirconium-stabilized spherical sili

23、ca packing with a hydrophilic (diol-type) molecular monolayer bonded phase having a pore size of 150 .L36 3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5 m aminopropyl silica.L37 Polymethacrylate gel packing having the capacity to separate proteins by molecular size over a ra

24、nge of 2,000 to 40,000D.L38 Methacrylate-based size-exclusion packing for water-soluble samples.L39 Hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.L40 Cellulose tris-3,5-dimethylphenylcarbamate coated porous silica particles,5 m to 20 m in diameter.L41 Immobilized -acid gl

25、ycoprotein on spherical silica particles, 5 m in diameter.L42 Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5 m in diameter.L43 Pentafluorophenyl groups chemically bonded to silica particles, 5 to 10 m in diameter.L44 A multifunctional support, which consists of

26、 a high purity, 60 , spherical silica substrate that has been bonded with a cationic exchanger, sulfonic acid functionality in addition to a conventional reversed phase C8 functionality.L45 Beta cyclodextrin bonded to porous silica particles, 5 to 10 m in diameter.L46 Polystyrene/divinylbenzene subs

27、trate agglomerated with quaternary amine functionalized latex beads, 10 m in diameter.L47 High capacity anion-exchange microporous substrate, fully functionalized with a trimethylamine group, 8 m in diameter.L48 Sulfonated, cross-linked polystyrene with an outer layer of submicron, porous,anion-exch

28、ange microbeads, 15 m in diameter.L49 A reversed-phase packing made by coating a thin layer of polybutadiene on to spherical porous zirconia particles, 3 to 10 m in diameter.L50 Multifunction resin with reversed-phase retention and strong anion-exchange functionalities. The resin consists of ethylvi

29、nylbenzene, 55 % cross-linked withdivinylbenzene copolymer, 3 to 15 m in diameter, and a surface area of not less than 350 m2/g, substrate is coated with quaternary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene.L51 Amylose tris-3,5-dimethylphenylcarba

30、mate-coated, porous, spherical, silica particles,5 to 10 m in diameter.L52 A strong cation exchange resin made of porous silica with sulfopropyl groups, 5 to 10 m in diameter.L53 Weak cation-exchange resin consisting of ethylvinylbenzene, 55 % cross-linked withdivinylbenzene copolymer, 3 to 15 m dia

31、meter. Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers. Capacity not less than 500 m in diameter.L54 A size exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads, about 13 m in diameter.L55 A strong cation ex

32、change resin made of porous silica coated with polybutadiene-maleic acid copolymer, about 5 m in diameter.L56 Isopropyl silane chemically bonded to totally porous silica particles, 3 to 10 m in diameter.L57 A chiral-recognition protein, ovomucoid, chemically bonded to silica particles, about 5 m in diameter, with a pore size of 120 angstroms.L58