10年心理学大会论文摘要医学心理.docx

1、10年心理学大会论文摘要医学心理医学心理医学心理专题报告分裂型人格研究新进展组织者：陈楚侨，中国科学院心理研究所心理健康重点实验室，中国科学院心理研究所神经心理学与应用认知神经科学实验室，北京，100101，rckchan主持者：谭淑平，北京回龙观医院 专题简介：分裂型人格是精神分裂症的易感人格特质，那些具有分裂型人格特点的个体在一生当中更有可能发展成为精神分裂症。过去在精神分裂症上的研究普遍认为精神分裂症病人存在语义加工障碍、明显的偏执观念、决策行为的改变、以及动机系统有关的正性情绪体验的损伤。然而，对于分裂型人格类似话题的研究尚少。本专题中的研究，通过行为的和神经电生理的手段，考察了分裂型

2、人格倾向个体在语义加工、偏执观念、决策行为以及期待性和消费性情绪体验上的表现。Symposium at the 13th Chinese Congress of Psychology:Most Recent Progress in the Study of Individuals with Schizotypal Personality FeaturesIntroduction of symposium: Schizotypal Personality Disorders (SPD) is predisposition of schizophrenia in the level of pers

3、onality organization. People with schizotypal personality features have higher risk to develop into schizophrenia in their later life time. Past studies in schizophrenia have proved that schizophrenic patients demonstrate semantic processing dysfunction, obvious paranoid ideation, changed in their d

4、ecision making behaviors, and deficits of motivation-system-related positive emotional experience. However, very few studies have been conducted on individuals with schizotypal personality features. The main aim of the current symposium is to give an overall view of most recent findings on individua

5、ls with schizotypal personality features, in particular, topics will cover semantic processing, paranoid thinking, decision making and anticipatory/consummatory affective with both behavioral and ERP paradigms.论文1:分裂型人格倾向个体语义加工的ERP研究王葵1,2,3王毅1,2,3严超1,2,3王玉娜1,2,3张琦1,2,3曹原4陈楚侨1,2*1中国科学院心理研究所神经心理学与应用认知

6、神经科学实验室，北京，100101；2中国科学院心理研究所心理健康重点实验室，北京，100101，rckchan；3中国科学院研究生院，北京，100049；4香港城市大学，香港特别行政区, 999077摘要：已有大量研究表明精神分裂症患者表现出语义加工的缺陷。迄今为止少有文献关注具有分裂型人格倾向的健康个体的语义加工过程。本研究使用词对语义关系判断任务探讨具有分裂型人格倾向个体的语义加工过程。刺激不同步时间为700毫秒。实验被试包含10个具有分裂型人格倾向的大学生和10个不具有该倾向的大学生。行为数据表明两组被试在反应时上均出现明显的启动效应，且不存在组间差异。两组被试对于有关词对的反应时间明

7、显短于对无关词对的反应时间。无关目标词在两组被试中均引起明显的N400。在300-400毫秒的时间窗口内，分裂性人格倾向个体组头皮前部N400差异波波幅要略大于控制组。这表明具有分裂型人格倾向个体似乎在使用补偿策略来进行语义加工。关键词：N400；语义；ERP；分裂型人格倾向Paper 1: An ERP Study on Semantic Processing in Individuals with Schizotypal Personality FeaturesWang Kui1,2,3 Wang Yi1,2,3 Yan Chao1,2,3 Wang Yuna1,2,3 Zhang Qi1

8、,2,3 Cao Yuan4 Raymond C. K. Chan1,2*1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China;2 Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101，China;3 Graduate S

9、chool , Chinese Academy of Sciences, Beijing 100049, China;4 City University of Hong Kong, Hong Kong 999077, ChinaAbstract: Semantic processing deficits have been observed in schizophrenia spectrum disorders. So far little work has been done in individuals with schizotypal personality features. In c

10、urrent study, we administered a semantic relatedness judgment task with word pairs to 20 participants (10 individuals in each group with and without schizotypal personality features). The SOA in the experiment was set at 700 ms. Behavioral priming effects were observed in both groups. No group effec

11、t or interaction between group and relatedness was obtained in the behavioral data. The ERP data showed a clear N400 with a wide scalp distribution for unrelated target words in both groups. Critically, the mean amplitudes for the difference wave between unrelated and related target words in 300-400

12、 ms time window tended to be larger in individuals with schizotypal personality features. These results may suggest a compensation for semantic processing in individuals with schizotypal personality features. Keywords: N400; semantic; ERP; schizotypal personality features论文2：分裂型人格倾向个体的延迟折扣与决策行为史艳芳1,

13、2,3陈楚侨1,2*严超1,2,3曹筱燕1,2,3宗纪刚1,2,31中国科学院心理研究所神经心理学与应用认知神经科学实验室，北京，100101；2中国科学院心理研究所心理健康重点实验室，北京，100101，rckchan；3中国科学院研究生院，北京，100049摘要：过去的研究提示精神分裂症病人会低估未来奖励的价值，进而不能有效的进行最优化的选择。分裂型人格作为精神分裂症的易感特质，目前还不清楚这些个体身上是否也存在与精神分裂症相类似的决策行为的改变。本研究旨在考察分裂型人格倾向个体的延迟折扣与决策行为的情况。34名分裂型人格与34名对照组参加了本研究，他们都完成一份考察延迟折扣率的问卷(Mo

14、netary-Choice Questionnaire, MCQ)和一个评估决策行为的赌博任务(Cambridge Gambling Task, CGT)。结果发现，相对于对照组，那些具有分裂型人格倾向的个体表现出显著增加的延迟折扣率，但他们在赌博任务上的表现却与对照组差不多。结果表明，尽管总体的决策行为表现上分裂型人格倾向的个体与对照组没有差别，但其相对增加的延迟折扣率提示他们也似乎存在对未来奖励价值低估的问题。关键词：分裂型人格；奖励；主观价值表征；最优选择行为Paper 2: Delay Discount and Decision Making in Individuals with S

15、chizotypal Personality FeaturesShi Yanfang1,2,3 Raymond C. K. Chan1,2*Yan Chao1,2,3 Cao Xiaoyan1,2,3 Zong Jigang1,2,31 Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101，China;2 Key Laboratory of Mental Health, Institut

16、e of Psychology, Chinese Academy of Sciences,Beijing 100101，China;3 Graduate School, Chinese Academy of Sciences, Beijing 100049，ChinaAbstract: Previous studies suggest that patients with schizophrenia usually underestimate potential values of future rewards and are most unlikely to make optimal cho

17、ice behavior. However, very little is known that whether individuals with schizotypal personality features have similar behavioral changes in their decision making. The current study aims to examine delay discount and decision making in individuals with schizotypal personality features. Thirty-four

18、individuals with schizotypal personality features and 34 comparison controls were administered the Monetary-Choice Questionnaire (MCQ) and the Cambridge Gambling Task (CGT). Results indicated that individuals with schizotypal personality features reported significant increased delay discounting rate

19、 comparing to the controls. However, there was no group difference in their performances on the gambling task. The findings suggested that individuals with schizotypal personality features demonstrate a similar deficit with schizophrenia in subjective representation of values for rewards but not a g

20、eneral deficit in gambling-task-captured decision making behavior.Key words: schizotypal; reward; subjective representation; optimal choice behavior 论文3：分裂型人格偏执观念相关的ERP研究李雪冰1,2黄佳1,2龚启勇3陈楚侨1,2*1 中国科学院心理研究所神经心理学与应用认知神经科学实验室，北京，100101；2 中国科学院心理研究所心理健康重点实验室，北京，100101，rckchan；3 四川大学华西医院影像系，成都，610041摘要： 本

21、研究的目的是采用事件相关电位(Event-related potential，ERP)技术来探讨分裂型人格偏执观念的潜在神经机制。通过SPQ (Schizotypal Personality Questionnaire)问卷筛查，共有33名大学生参加了此研究，其中17名入组SPD (schizotypal personality disorder)组(分数35)，16名入组非SPD组(分数22)。实验采用被试输数字，“别人”猜的方法，诱导被试产生“被人看穿”的想法。首先让被试在屏幕上随机输入一个数字(范围1-9)，之后给出一个反馈的数字，告诉被试这个反馈的数字，是其他人猜到的。但实际上，反馈数

22、字是由电脑程序控制。对正确反馈相关的ERPs减去错误反馈相关的ERPs得到的差异波进行分析，结果发现SPD组的P350成分较非SPD组的波峰明显降低，P350的波幅与被试SPQ的得分成负相关。并且，SPD组P350主要分布在顶叶皮层区域，非SPD组则分布在前额叶区域。当前结果为SPD人群存在明显的偏执观念提供了电生理证据，并且指出ERP中的P350成分可能反应了这种多疑观念。此外，SPD个体可能更多动用顶叶皮层参与偏执想法的加工。关键词：分裂型人格特质；偏执观念；事件相关电位Paper 3:Event-related Potential Correlates of Paranormal Tho

23、ughts in Individuals with Schizotypal Personality FeaturesLi Xuebing, 2 Huang Jia1, 2Gong Qiyong3Chen Chuqiao1, 2*1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101，China;2 Key Laboratory of Mental Health, Institute o

24、f Psychology, Chinese Academy of Sciences, Beijing 100101, China;3 Huaxi MR Research Centre, Department of Radiology, West China Hospital/West China School of Medicine, Sichuan University, Chengdu 610041, ChinaAbstract: Paranoid ideation is a common clinical symptom of schizophrenia. This study aime

25、d to explore the underlying neural mechanism of paranoid thoughts in individuals with SPD using an event-related potential (ERP) paradigm. Participants were selected from the colleges in Beijing screened by the Schizotypal Personality Questionnaire (SPQ), and were classified into individuals with an

26、d without SPD features based on the SPQ score. Seventeen (scores35) and 16 (scores22) individuals were in the SPD and non-SPD group, respectively. The experiment was designed to induce the feeling of being seen through. The participants were instructed to input a digit from 1 to 9 at random on the c

27、omputer and were told that others would guess which number they had been input, then this number guessed by others would be shown on the screen as a feedback. However, the procedure was actually controlled by the computer. Difference waves were gained by subtracting wrong guess ERPs from right guess

28、 ERPs. The findings showed P350 amplitude was significantly reduced in SPD group relative to non-SPD group, which suggested that SPD individuals have more paranoid thoughts than non-SPD ones. The P350 of difference wave was negatively correlated with the SPQ cognitive-perception factor, which provid

29、ed preliminary electrophysiological evidence for the association of paranoid ideation and schizotypal personality. Besides, the P350 was broadly distributed in the frontal region in the non-SPD group and in the parietal region in the SPD group, which suggested that parietal cortex may play a role in

30、 the onset of suspicious thoughts.Key words: schizotypal personality; paranormal thoughts; ERP 论文4:分裂型人格特质的情绪体验和动机：预实验研究严超1,2,3陈楚侨1,2*曹筱燕1,2,3王玉娜1,2,3罗泽4宗纪刚1,2,31中国科学院心理研究所神经心理学与应用认知神经科学实验室，北京，100101；2中国科学院心理研究所心理健康重点实验室，北京，100101，rckchan；3中国科学院研究生院，北京，100049；4中国人民大学，北京，100872摘要：情感受限被普遍认为是分裂型人格障碍的一个

31、重要组成部分。然而，很少有研究使用实验去探讨分裂型人格障碍群体的情绪体验和动机行为。本研究着眼于从奖励和惩罚的角度去弄清这个群体的期待性情绪体验、消费性情绪体验和动机。48名被试(28名控制组和20名分裂型人格倾向组)参加了本研究，他们填写了一些有关情绪体验和动机的问卷，同时还参与了奖励延迟任务(Monetary Incentive Delay, MID)。在自我报告的问卷中，分裂型人格倾向的人群相对控制组报告出更多情绪体验问题；而他们报告出更少趋向动机和更多规避动机。在MID实验中，分裂型人格群体相对于控制组在惩罚情境下，主观报告出更多负性效价的期待性情绪体验和消费性情绪体验，而在奖励情境下

32、，没有发现和控制组的不一致表现。同时，也没有发现被试趋向动机和规避动机的差别。这个研究结果表明分裂型人格人群可能对于惩罚或者失败更为敏感，表现出更负性的情绪体验，反过来，这可能和分裂型人格障碍中的人际交往的因素有关系。关键词：分裂型人格障碍；情绪；动机；奖励；惩罚Paper 4:Anticipatory/Consummatory Affect and Motivation in Individuals with Schizotypal Personality Features: A Pilot StudyYan Chao1,2,3 Raymond C. K. Chan1,2* Cao Xiaoyan1,2,3 Wang Yuna1,2,3 Luo Zeyu4 Zong Jigang1,2,31 Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Scie