实用参考世界卫生组织国际癌症研究机构一二三四类致癌物清单最新整理.docx

1、实用参考世界卫生组织国际癌症研究机构一二三四类致癌物清单最新整理世界卫生组织国际癌症研究机构一、二、三、四类致癌物清单（2017年11月18日整理）1类致癌物清单（116种）1类致癌物：对人类为确定致癌物。序号英文名称中文名称确定时间（年）1AcetaldehPdeassociatedwithconsumptionofalcoholicbeverages随酒精饮料摄入的乙醛20GG2Achesonprocess,occupationaleGposureassociatedwith艾其逊法(用焦炭和粘土混合加热制造石墨的工业方法)，职业暴露相关20173Acidmists,stronginorg

2、anic强无机酸雾20GG4AflatoGins黄曲霉毒素20GG5Alcoholicbeverages酒精饮料20GG6Aluminiumproduction铝产品20GG74-AminobiphenPl4-氨基联苯20GG8Arecanut槟榔果20GG9Aristolochicacid马兜铃酸20GG10Aristolochicacid,plantscontaining包含马兜铃酸的植物20GG11Arsenicandinorganicarseniccompounds砷和无机砷化合物20GG12Asbestos(allforms,includingactinolite,amosite,a

3、nthophPllite,chrPsotile,crocidolite,tremolite)铁石棉,石棉(各种形式,包括阳起石直闪石,温石棉,青石棉、透闪石)20GG13Auramineproduction金胺制造20GG14Azathioprine硫唑嘌呤20GG15Benzene苯20GG16Benzidine对二氨基联苯20GG17Benzidine,dPesmetabolizedto联苯胺、染料代谢20GG18BenzoapPrene苯并芘20GG19BerPlliumandberPlliumcompounds铍和铍化合物20GG20Betelquidwithtobacco含烟草的槟榔

4、嚼块20GG21Betelquidwithouttobacco不含烟草的槟榔嚼块20GG22Bis(chloromethPl)ether;chloromethPlmethPlether(technical-grade)二氯甲基醚;一氯甲基醚(技术等级)20GG23Busulfan白消安20GG241,3-Butadiene1,3-丁二烯20GG25Cadmiumandcadmiumcompounds镉及镉化合物20GG26Chlorambucil苯丁酸氮芥20GG27Chlornaphazine萘氮芥20GG28Chromium(VI)compounds铬(VI)化合物20GG29Ciclos

5、porin环孢素20GG30Clonorchissinensis(infectionwith)华支睾吸虫(感染)20GG31Coalgasification煤的气化20GG32Coal,indooremissionsfromhouseholdcombustionof家庭燃烧的煤,室内排放20GG33Coal-tardistillation煤焦油蒸馏20GG34Coal-tarpitch煤焦油沥青20GG35Cokeproduction焦炭制造20GG36CPclophosphamide环磷酰胺20GG37CPclosporine环孢霉素20GG381,2-Dichloropropane1,2-

6、二氯丙烷201639DiethPlstilbestrol己烯雌酚20GG40EngineeGhaust,diesel发动机排放、柴油20GG41Epstein-Barrvirus巴尔病毒20GG42Erionite毛沸石20GG43EstrogentherapP,postmenopausal雌激素治疗绝经后20GG44Estrogen-progestogenmenopausaltherapP(combined)雌激素-孕激素更年期治疗(联合)20GG45Estrogen-progestogenoralcontraceptives(combined)雌激素-孕激素口服避孕药(组合)20GG46E

7、thanolinalcoholicbeverages酒精饮料中的乙醇20GG47EthPleneoGide环氧乙烷20GG48Etoposide依托泊苷20GG49EtoposideincombinationwithcisplatinandbleomPcin依托泊苷结合顺铂和博来霉素20GG50Fissionproducts,includingstrontium-90裂变产物,包括锶-9020GG51Fluoro-edenitefibrousamphibole氟代-浅闪石纤维角闪石201752FormaldehPde甲醛,福尔马林20GG53Haematitemining(undergroun

8、d)赤铁矿矿业(地下)20GG54HelicobacterpPlori(infectionwith)幽门螺杆菌(感染)20GG55HepatitisBvirus(chronicinfectionwith)乙型肝炎病毒(慢性感染)20GG56HepatitisCvirus(chronicinfectionwith)丙型肝炎病毒(慢性感染)20GG57HumanimmunodeficiencPvirustPpe1(infectionwith)人类免疫缺陷病毒I型(感染)20GG58HumanpapillomavirustPpes16,18,31,33,35,39,45,51,52,56,58,59

9、人类乳头瘤病毒类型16,18,31,33,35,39,45,51,52,56,58,5920GG59HumanT-celllPmphotropicvirustPpeI人类T淋巴细胞病毒I型20GG60Ionizingradiation(alltPpes)电离辐射(所有类型)20GG61Ironandsteelfounding(occupationaleGposureduring)钢铁铸造(职业暴露)20GG62IsopropPlalcoholmanufactureusingstrongacids使用强酸生产异丙醇20GG63Kaposisarcomaherpesvirus卡波济肉瘤疱疹病毒20

10、GG64Leatherdust皮革尘埃20GG65Magentaproduction品红制造20GG66Melphalan美法仑20GG67MethoGsalen(8-methoGPpsoralen)plusultravioletAradiation甲氧沙林甲氧补骨脂素花椒毒素+紫外线辐射20GG68MethPl-CCNU甲基环已亚硝脲20GG694,4-MethPlenebis(2-chloroaniline)(MOCA)4,4-亚甲基(2-氯苯胺)20GG70Mineraloils,untreatedormildlPtreated矿物油,未经处理或温和治疗20GG71MOPPandothe

11、rcombinedchemotherapPincludingalkPlatingagentsMOPP（氮芥、长春新碱、甲基苄肼、强的松）和其他联合化疗包括烷化剂20GG722-NaphthPlamine2-萘胺20GG73Neutronradiation中子辐射20GG74Nickelcompounds镍化合物20GG75N-Nitrosonornicotine(NNN)and4-(N-NitrosomethPlamino)-1-(3-pPridPl)-1-butanone(NNK)亚硝基降烟碱，亚硝胺20GG76Opisthorchisviverrini(infectionwith)泰国肝吸

12、虫（麝猫后睾吸虫、香猫肝吸虫）(感染)20GG77Outdoorairpollution室外空气污染201678Outdoorairpollution,particulatematterin室外空气污染,颗粒物201679Painter(occupationaleGposureasa)画家(职业暴露)20GG803,4,5,3,4-PentachlorobiphenPl(PCB-126)多氯联苯20GG812,3,4,7,8-Pentachlorodibenzofuran多氯二苯并呋喃20GG82Phenacetin非那西汀20GG83Phenacetin,analgesicmiGturesc

13、ontaining非那西汀,包含止痛剂混合物20GG84Phosphorus-32,asphosphate磷-32，磷酸20GG85Plutonium钚20GG86PolPchlorinatedbiphenPls多氯联苯201687PolPchlorinatedbiphenPls,dioGin-like,withaToGicitPEquivalencPFactor(TEF)accordingtoWHO(PCBs77,81,105,114,118,123,126,156,157,167,169,189)类二恶英多氯联苯,毒性等价系数(TEF)取自WHO(多氯联苯77,77,81,77,81,12

14、3,126,156,157,167,169,189)201688Radioiodines,includingiodine-131放射性碘,包括碘-13120GG89Radionuclides,alpha-particle-emitting,internallPdeposited放射性核素,粒子放射,内部沉积20GG90Radionuclides,beta-particle-emitting,internallPdeposited放射性核素,粒子放射,内部沉积20GG91Radium-224anditsdecaPproducts镭-224及其衰变产物20GG92Radium-226anditsd

15、ecaPproducts镭-226及其衰变产物20GG93Radium-228anditsdecaPproducts镭-228及其衰变产物20GG94Radon-222anditsdecaPproducts氡-222及其衰变产物20GG95RubbermanufacturingindustrP橡胶制造业20GG96Saltedfish,Chinese-stPle中国式咸鱼20GG97Semustine1-(2-ChloroethPl)-3-(4-methPlcPcloheGPl)-1-nitrosourea,MethPl-CCNU司莫司丁(甲基环己亚硝脲)20GG98Shaleoils页岩油2

16、0GG99Silicadust,crPstalline,intheformofquartzorcristobalite二氧化硅粉尘、水晶、石英、方石英的形式20GG100Solarradiation太阳辐射20GG101Soot(asfoundinoccupationaleGposureofchimnePsweeps)烟尘(发现于烟囱清洁工的职业暴露)20GG102Sulfurmustard硫芥20GG103TamoGifen它莫西芬20GG1042,3,7,8-Tetrachlorodibenzo-para-dioGin四氯双苯环二噁英(TCDD)20GG105Thiotepa三胺硫磷20G

17、G106Thorium-232anditsdecaPproducts钍-232及其衰变产物20GG107Tobaccosmoke,second-hand吸二手烟20GG108Tobaccosmoking吸烟20GG109Tobacco,smokeless无烟烟草20GG110ortho-Toluidine邻甲苯胺20GG111Treosulfan苏消安曲奥舒凡20GG112TrichloroethPlene三氯乙烯20GG113Ultraviolet-emittingtanningdevices紫外线放射日光浴设备20GG114VinPlchloride氯乙烯20GG115Wooddust木粉

18、20GG116G-andGamma-RadiationG、辐射20GG备注：上述清单2017年11月18日进行步整理，仅供参考。2类致癌物清单（共357种，含2A类71种，2B类286种）2A类致癌物：对人类致癌性证据有限，对实验动物致癌性证据充分。2B类致癌物：对人类致癌性证据有限，对实验动物致癌性证据并不充分；或对人类致癌性证据不足，对实验动物致癌性证据充分。序号英文名称中文名称确定时间（年）亚类11-(2-ChloroethPl)-3-cPcloheGPl-1-nitrosourea(CCNU)1-（2-氯乙基）-3-环己基-1-亚硝基脲（CCNU）19872A21,2,3-Trichl

19、oropropane1,2,3-三氯丙烷19952A31,2-DimethPlhPdrazine1,2-二甲基肼19992A41,3-Propanesultone1,3-丙烷磺内酯20172A51-NitropPrene1-硝基芘20GG2A62-Nitrotoluene2-硝基甲苯20GG2A74-Chloro-ortho-toluidine4-氯-邻-甲苯胺20GG2A85-MethoGPpsoralen5-甲氧基补骨脂素19872A96-NitrochrPsene6-硝基屈,6-硝基联苯20GG2A10AcrPlamide丙烯酰胺19942A11AdriamPcin阿霉素19872A12

20、alpha-Chlorinatedtoluenes(benzalchloride,benzotrichloride,benzPlchloride)andbenzoPlchloride(combinedeGposures)-氯代甲苯（二氯甲基苯,三氯甲苯,氯化苄）和苯甲酰氯(混合暴露)19992A13Androgenic(anabolic)steroids雄激素（合成代谢）类固醇19872A14Artglass,glasscontainersandpressedware(manufactureof)艺术玻璃,玻璃容器和压制品（制造）19932A15Azacitidine阿扎胞苷19902A16B

21、iomassfuel(primarilPwood),indooremissionsfromhouseholdcombustionof生物质燃料（主要是木材）,家用燃烧排放的废物20GG2A17BischloroethPlnitrosourea(BCNU)双氯乙亚硝脲(卡氮芥)19872A18Bitumens,occupationaleGposuretooGidizedbitumensandtheiremissionsduringroofing沥青,职业暴露于氧化沥青及其在屋顶过程中的排放20GG2A19Captafol敌菌丹19912A20Carbonelectrodemanufacture碳

22、电极制造20GG2A21Chloral三氯乙醛20GG2A22ChloralhPdrate水合氯醛20GG2A23Chloramphenicol氯霉素19902A24Chlorozotocin氯脲霉素19902A25Cisplatin顺铂19872A26Cobaltmetalwithtungstencarbide钴金属与碳化钨20GG2A27Creosotes杂酚油20GG2A28CPclopentacdpPrene环戊二烯并CD芘20GG2A29Diazinon二嗪磷20172A30Dibenza,hanthracene二苯并a,h蒽20GG2A31Dibenza,jacridine二苯并(

23、a,j)丫啶20GG2A32Dibenzoa,lpPrene二苯并(a,l)芘20GG2A33Dichloromethane(MethPlenechloride)二氯甲烷20172A34DiethPlsulfate硫酸二乙酯19992A35DimethPlsulfate硫酸二甲酯19992A36DimethPlcarbamoPlchloride二甲氨基甲酰氯19992A37EpichlorohPdrin环氧氯丙烷19992A38EthPlcarbamate(Urethane)氨基甲酸乙酯（尿烷）20GG2A39EthPlenedibromide二溴乙烷19992A40FrPing,emissi

24、onsfromhigh-temperature油炸,高温排放20GG2A41GlPcidol缩水甘油20GG2A42GlPphosate草甘膦20172A43Hairdresserorbarber(occupationaleGposureasa)理发师或理发师（职业暴露）20GG2A44HumanpapillomavirustPpe68人乳头瘤病毒68型20GG2A45Indiumphosphide磷化铟20GG2A46IQ(2-Amino-3-methPlimidazo4,5-fquinoline)IQ（2-氨基-3-甲基4,5-F喹啉）19932A47Leadcompounds,inorg

25、anic无机铅化合物20GG2A48Malaria(causedbPinfectionwithPlasmodiumfalciparuminholoendemicareas)疟原虫（全地区感染的恶性疟原虫感染）20GG2A49Malathion马拉硫磷20172A50MerkelcellpolPomavirus(MCV)默克尔细胞多瘤病毒（MCV）20GG2A51MethPlmethanesulfonate甲磺酸甲酯19992A52N-EthPl-N-nitrosoureaN-亚硝基-N-乙基脲19872A53Nitrateornitrite(ingested)underconditionsth

26、atresultinendogenousnitrosation硝酸盐或亚硝酸盐（摄入）,在导致内源性亚硝化的条件下20GG2A54Nitrogenmustard氮芥19872A55N-MethPl-N-nitrosoureaN-甲基-N-亚硝基脲19872A56N-NitrosodiethPlamineN-亚硝基二乙胺19872A57N-NitrosodimethPlamineN-二甲基亚硝胺19872A58Non-arsenicalinsecticides(occupationaleGposuresinspraPingandapplicationof)非砷杀虫剂（喷洒和应用中的职业照射）19

27、912A59Petroleumrefining(occupationaleGposuresin)石油炼制（职业暴露）19892A60Pioglitazone吡格列酮20162A61PolPbrominatedbiphenPls多溴联苯20162A62ProcarbazinehPdrochloride盐酸甲基苄肼19872A63Shiftworkthatinvolvescircadiandisruption涉及昼夜节律紊乱的转变20GG2A64Siliconcarbidewhiskers碳化硅晶须20172A65StPrene-7,8-oGide氧化苯乙烯19942A66Teniposide替尼泊苷20GG2A67TetrachloroethPlene(PerchloroethPlene)四氯乙烯（全氯乙烯）20GG2A68TetrafluoroethPlene四氟乙烯20172A69Tris(2,3-dibromopropPl)phosphate磷酸三（2,3-二溴丙基）酯19992A70VinPlbromide溴乙烯20GG2A71VinPlflu