各种实验动物权威麻醉用量.docx

1、各种实验动物权威麻醉用量小鼠(mouse)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.02-0.05mg/kg IV,IM,SC 1.2mg/kg IP鎮靜劑 Acepromazine 0.75mg/kg IM Diazepam 5mg/kg IP Ketamine 20mg/kg IM注射麻醉劑 Ketamine 22-44mg/kg IM 100mg/kg IP 25mg/kg IV Pentobarbital 15mg/kg IV (以生理食鹽水10倍稀釋) 40-80mg/kg IP Thiopental 25mg/kg IV 50mg/kg IP Thiamyla

2、l 25-50mg/kg IV Tribromoethanol 0.2ml/10g IP (Avertin) (240mg/kg) (1.2 solution)混合注射麻醉劑 KetamineXylazine 50mg15mg/kg IM,IP 90-120mg10mg/kg IM,IP KetamineAcetylpromazine 100mg2.5mg/kg IM吸入麻醉劑 Carbon dioxide 50-70和氧混合 Inhalation Halothane 1-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 1-4 to effect I

3、nhalation Methoxyflurane 0.5-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC 4mg/kg IP Butorphanol 1-5mg/kg q2-4h SC,IM Pentacozine 10mg/kg q2-4h SC,IM,IV不推薦使用的藥物 Chloroform Ether Chloral Hydrate 370-400mg/kg IP Carbon tetrachloride Chlorpromazine Trichloroethylene TribromoethanolIM：肌肉注射 IV

4、：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)大鼠(Rat)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.02-0.05mg/kg IV,IM,SC鎮靜劑 Acepromazine 5mg/kg IM,SC Diazepam 2.5mg/kg IP Xylazine 13mg/kg IM Ketamin

5、e 22mg/kg IM 20mg/kg IP注射麻醉劑 Ketamine 44mg/kg IM 40-160mg/kg IP 50mg/kg IV Fentanyl-droperidol 0.2-0.6ml/kg IP Pentobarbital 30-40mg/kg IV 30-50mg/kg IP Urethane 1000mg/kg IP混合注射麻醉劑 KetamineXylazine 40-80mg5-10mg/kg IM,IP KetaminePentobarbital 44mg25mg/kg (K)IM,(P)IP KetamineAcetylpromazine 75-80mg2

6、.5mg/kg (K)IM,(A)IM吸入麻醉劑 Carbon dioxide 50-80和20-50氧混合 Inhalation Halothane 1-3 to effect Inhalation 0.5-1.5(維持) Isoflurane 1-5 to effect Inhalation Methoxyflurane 1-3 to effect Inhalation Enflurane 3-4 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorphanol 1-5mg/kg q2-4h SC Pentacozine

7、10mg/kg q2-4h SC不推薦使用的藥物 Chloroform Chloral Hydrate 300-450mg/kg IP Chlorpromazine Tribromoethanol 300mg/kg IPIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)沙鼠(Gerbil)麻醉劑量表藥 物

8、 劑 量 途 徑 麻醉前給藥Atropin 0.02-0.05mg/kg IV,IM,SC鎮靜劑 Diazepam 5-10mg/kg IP Ketamine 22mg/kg IM注射麻醉劑 Ketamine 44mg/kg IMFentanyl-droperidol 0.15ml/kg IP Pentobarbital 30mg/kg IV 60mg/kg IP,SC Tribromoethanol 0.2-0.25ml/10g IP (Avertin) (250-300mg/kg)混合注射麻醉劑 KetamineXylazine 50mg2mg/kg IP吸入麻醉劑 Halothane 1

9、-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 1-4 to effect Inhalation Methoxyflurane 1-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorphanol 1-5mg/kg q2-4h SC Pentacozine 10mg/kg q2-4h SC不推薦使用的藥物 Chloroform Ether AcepromazineIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.

10、實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)雪貂(ferret)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.05mg/kg IV,IM,SC鎮靜劑 Acepromazine 0.2-0.5mg/kg IM,SC Diazepam 2mg/kg IM Xylazine 1mg/kg IM,SC Ketamine 10mg/kg IM注射麻醉劑 Ketamine 30-60mg/kg IM Pen

11、tobarbital 30-36mg/kg IP Thiopental 60mg/kg IP混合注射麻醉劑 KetamineXylazine 10-25mg1-2mg/kg IM KetamineAcetylpromazine 20-35mg0.2-0.35mg/kg SC,IMKetamineDiazepam 25-35mg2-3mg/kg IM吸入麻醉劑 Halothane 3-4 to effect Inhalation 0.5-1.5(維持) Isoflurane 2-5 to effect Inhalation Methoxyflurane 1-3 to effect Inhalat

12、ion止痛劑 Meperidine 5-10mg/kg q2-4h IM,SC,IV Butorphanol 0.1-0.5mg/kg q12h IM Pentacozine 5-10mg/kg q4h IM不推薦使用的藥物 PentobarbitalIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.實驗動物管理與使用指南。(中華實驗動物學會出版2004) 2.Clinical laboratory animal medicine。(K,Hrapkiewicz Iowa State University Press1998)倉鼠

13、(Hamster)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.05-0.1mg/kg SC注射麻醉劑 Ketamine 200mg/kg IP Pentobarbital 70-90mg/kg IP Urethane 1500mg/kg IP混合注射麻醉劑 KetamineXylazine 80-100mg7-10mg/kg IP KetamineDiazepam 40-100mg5mg/kg IP KetamineAcetylpromazine 150mg5mg/kg IM吸入麻醉劑 Halothane 1-4 to effect Inhalation Isofluran

14、e 1-4 to effect Inhalation Methoxyflurane 1-3 to effect Inhalation止痛劑 Meperidine 20mg/kg q2-3h IM,SC Butorphanol 1-5mg/kg q2-4h SC Pentacozine 10mg/kg q2-4h SC不推薦使用的藥物 Chloral Hydrate 270-360mg/kg IP Fentanyl-droperidolIM：肌肉注射 IV：靜脈注射 SC：皮下注射 IP：腹腔注射 Inhalation：吸入Reference: 1.Clinical laboratory ani

15、mal medicine。(K,Hrapkiewicz Iowa State University Press1998)天竺鼠(Guinea Pig)麻醉劑量表藥 物 劑 量 途 徑 麻醉前給藥Atropin 0.05-0.1mg/kg SC注射麻醉劑 Pentobarbital 25-35mg/kg IP Urethane 1500mg/kg IV,IP混合注射麻醉劑 KetamineXylazine 40mg2mg/kg (K)IP,(X)IM KetamineDiazepam 20-30mg1-2mg/kg IM KetamineAcetylpromazine 25-55mg0.75-3mg/kg IM吸入麻醉劑 Halothane 0.5-4 to effect Inhalation Isoflurane 2