1、病例分享,浙江医院ICU,基本情况,患者钟XX,男性,89岁。#因“反复咳嗽、咳痰5天”入呼吸科就诊。#入院诊断:#急性支气管炎,2型糖尿病,冠 心病 心功能II级,原发性高血压病2级。#,基本情况,2010-11-13突发意识丧失,伴全身抽搐。#以“癫痫持续状态”转入神经内科。#神经内科住院期间,癫痫反复发作,予气管插管,呼吸机应用。#随后患者出现肌钙蛋白及心肌酶谱升高,肌酐水平逐渐升高。#2010-11-18转入我科接受进一步治疗。#,经验用药:#特治星针4.5 vp q8h,痰培养:#暂无结果,36.8,11.6*109/L,83.3%,198.9mg/L,2010-11-25 加用替考
2、拉宁0.2 ivgtt qd联合特治星针,2101-11-23 气管切开痰培养:#铜绿假单胞菌+阴沟肠杆菌+,38.3,14.1*109/L,83%,198.9mg/L,2011-11-29 停用特治星针,改美罗培南针0.5g ivgtt q8h联合替考拉宁抗感染,开始出现反复的低血压,难以纠正的低蛋白血症痰培养结果同前:#铜绿假单胞菌+阴沟肠杆菌+,38.0,8.5*109/L,77.4%,139.1mg/L,2010-12-05 停用替考拉宁针,单用美罗培南针,血流动力学趋于稳定痰培养:#阴沟肠杆菌+,37.3,5.6*109/L,70.2%,42.5mg/L,2010-12-20 停用美
3、罗培南针,患者血流动力学稳定,需要安博维片降压痰培养同前:#阴沟肠杆菌+,37.0,4.5*109/L,58%,41.7mg/L,2010-12-27 根据痰培养结果经验性加用比阿培南针0.3 ivgtt q8h,痰培养:#产酸克雷伯氏菌+鲍曼复合醋酸钙不动杆菌+,37.3,5.9*109/L,55.5%,94.0mg/L,2011-1-12 比阿培南应用两周,予停用,患者一般状况可,已经开始脱机锻炼白细胞数较前升高,暂时未应用抗生素,37.0,11.1*109/L,59.2%,30.9mg/L,2011-1-17 体温升高,予舒普深3g vp q12h联合科赛斯50mg ivgtt qd抗感
4、染(首剂加量),患者痰量增加痰培养:#铜绿假单胞菌+鲍曼复合醋酸钙不动杆菌+,38.0,10.4*109/L,60.9%,38.3mg/L,2010-1-20 血培养阳性,抗生素改为替考拉宁针0.4g ivgtt qd+丰迪针1g vp q12h,血培养:#金黄色葡萄球菌患者再次出现反复低血压,补液后回升,37.7,10.1*109/L,62.2%,39.3mg/L,2011-1-22考虑患者肾脏功能较差,改替考拉宁针为斯沃针 0.6g ivgtt q12h2011-1-30患者体温无下降,经验性加用依替米星针400mg ivgtt qd,痰培养:#鲍曼复合醋酸钙不动杆菌+(阿米卡星外全耐),37.9,8.7*109/L,68%,17mg/L,2011-2-1 患者体温降至正常,停用抗生素,37.1,9.4*109/L,66.5%,19.8mg/L,