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科技英语与论文写作
JIANGSUUNIVERSITY
课程结业作业
科技英语与论文写作
学院名称:
机械工程学院
专业班级:
研1402
学生姓名:
XX
学生学号:
XXX
任课教师姓名:
XX
2015年5月
XX
研机械工程学硕1402
No.S1403062
Exam1
DescribetheprocessofsubmittingyourpapertotheEnglishJournalwiththeillustrationforeachstep.
(1)Createyournewaccount
(2)ConfirmnewaccountbyQQmail
(3)Loginyouraccount
(4)Registration
(5)Submitnewmanuscript
Exam2
EnvironmentalpollutionwiththeChinesecommoncancertrends
Dingrui
JiangsuUniversity
e-mail:
569946564@
Abstract:
Intheprocessofcanceroccurrenceanddevelopment,morethan70%ofthecarcinogensandpromotersareassociatedwithenvironmentalpollutionorhumanbehaviors.Arsenic,asbestos,benzene,smoking,air-pollution,etc.havebeenclassifiedbyIARCasenvironmentalpollutantsthatarecarcinogenictohuman.ResearchforcancerinChinashowsthatfoodcontaminatedbyfungusorinfectedbyhumanoccupationalexposuretoairpollutedbyradon,andexposuretoindoorairpollutedbyburningsmokycoalarecausesofcancers.Thecurrentstudyreviewstheenvironmentalpollution,theepidemicofcancersofesophagus,stomach,liver,cervixuteri,lung,andtheirtypicalcasestoprovidescientificreferencesforworkingoncancerprevention.
Keywords:
environmentpollution;cancer;epidemiology
1Introduction
Environmentalpollutionisaproblemintoday'ssocialattention.AccordingtothestateenvironmentalprotectiondepartmentoftheChinaenvironmentbulletin,2012,China'sYellowRiverbasin,huaiheriverandliaoriversectionofbadVkindofwaterqualitydetectionrateofmorethan10%,classI~IIIwaterqualitydetectionrateof60%,47%,44%respectively[1].Thenationalkeyenvironmentalprotectioncitiesatmosphericenvironmentalairqualitysuccessrateis23.9%;Atmosphericparticulatematterintheannualaverageconcentrationofl7citieswhichis57.2%;KeyenvironmentalprotectioncitieswhichNO2annualaverageconcentrationof27.4%.TheabovedatashowsthatChina'satmosphericair,andwaterenvironmentalpollutionmakespeopleworry.However,theconventionalmonitoringdataisnotthatthepollutionoftheenvironmentwithChineseresidentsincancer.InthisbriefreviewaboutthepollutionoftheenvironmentandcommontypesofcancerthatpopulartrendresearchinChina.
2Environmentalcontaminantsandhumancarcinogen
Intheprocessofcanceroccurrenceanddevelopment,morethan70%ofallcancerandpromotecancerfactorscloselyrelatedtoenvironmentalpollutionandhumanbehavior.Carcinogenicsubstanceofenvironmentalpollutionisoneoftheimportantreasonsfortheincreaseincancer.Environmentalpollutantscancausecancerinhumansthroughair,waterandsoilpollutiontotheenvironment,carcinogenicpartswidely,includinglung,throat,ovarian,breast,skin,bladder,nosepharynx,kidneyandhematopoieticsystem,etc.Theworldhealthorganization(who)internationalcancerresearchcenterintheworldcancerreport2014,liststhe18typesofenvironmentalpollutantscausecancerinhumans,asbestos,arsenicanditsinorganiccompoundssuchasbenzene,1,3-butadiene,hexavalentchromiumcompounds,suchasdieselexhaust(table1)[2]
Table1EnvironmentalpollutantsclassifiedbyIARCas
group1,carcinogenictohumans
Nameofcarcinogen
Carcinogenicparts/cancer
Themainpollutionoftheenvironment
Arsenicandinorganic
Asbestos(allkinds)
benzene
1,3-butadiene
Chromiumcompound(6)
Dieselexhaust
erionite
Epoxyethane
formaldehyde
Familycoal(indoorrow
Putthings)
Outdoorairpollution
Outdoorsuspendedparticlesfouling
Withtheair
Polychlorinatedbiphenyls(PCBS)
Radonanditsdecay
Crystallinesilicadust
2,3,7,8-fourchlorine
Benzene-to-secondevil
(TCDD)
Tobaccosmokingandsecondhandsmoke
trichloroethylene
Lung,skin,bladder
Throat,lungs,mesothelioma,ovaries
Acutelymphoblasticleukemia
Leukemia,lymphoma
lung
lung
mesothelioma
Mammarygland,lymphatictumour
Nasopharyngealcarcinoma,leukemia
lung
lung
lung
Theskin
lung
lung
Allcancercombinations
lung
renal
water
air
Airemission(engine)
air
Waterandsoil
Airemission(engine)
Air(local)only
Air(indoor)
Air(indoorandoutdoor)
Air(indoor)
air
air
Food,air(indoor)
Air(indoor)
Air
Food,soil
Air(indoor)
Water,food,
3ThepopulartrendofChinesecommontypesofcancer
China'spopulationofcancerincidenceintherapidriseinrecent40years,cancerspectrumisalsochanging.Inthe1970s,China's850millionpeopleinthecauseofdeathreviewindicatesthatallpartsofChinahavecancer,thecauseofdeathinthethirdnationalcancerdeaths,10.1%ofalldeaths,thetop10cancerdeathswasfollowedbygastriccancer,esophaguscancer,livercancer,cervicalcancer,lungcancer,colorectalcancer,leukemia,nasopharyngealcarcinoma,breastcancer,brainandcentralnervoussystemtumors[3].Eachpartoftheregionaldifferfromthatofdeathlevelanddistributionofcancer.Somecommontypesofcancerinthelowlevelofeconomy,thelivingenvironment,diet,healthandnutritionalstatusofrelativelypoorareasmoresee.Inareaspronetocancerofthefood,water,soil,bodyfluidsamples,usuallyenvironmentpollutingcarcinogensdetectionrateandlowlevelhigherthanthatofcancerarea.Atthebeginningofthe21stcentury,China'sthirdnationalcauseofsamplingsurvey,thesamplearearesidentscancerdeathsisthecauseofdeathinthesecondplace,22.3%ofalldeaths,thetop10cancerdeaths,inturn,islungcancer,livercancer,gastriccancer,esophagealcancer,colorectalcancer,leukemia,brainandcentralnervoussystemtumors,femalebreastcancer,andpancreaticcancerandmultiplemyeloma[4].
4EnvironmentalpollutionandinfectionofpathogenicmicroorganismsandtheChinesepartofthecommontypesofcancer
4.1Esophagealcancer
Esophagealcancerissecondinthemid1970sChinacancerdeath,deathrateof23.4/10(31.7/10men,womenof15.9/10),higherleveloftheworld.Henan,hebei,shanxi,sichuan,jiangsu,fujian,guangdong,xinjiangandotherprovincesandautonomousregionshaveahighincidenceofesophagealcancerin[3]intheregion.HenanlinzhoucityinChina,esophagealcancermortalityaccountedfor60%ofcancerdeathsinthe1970s,esophagealcancermortalityinbothmenandwomenarerespectively7.1timesand9.5timesofthecountry.Internationalcancerresearchhasclearlysmoking,drinkingalcoholisoneoftheimportantriskfactors[2]happenesophagealcancer.ThecauseofesophagealcancerinChina,inadditiontosmokinganddrinking,somechemicalcarcinogens,suchasnitrosamine,mycotoxins,traceelementsandnutritionimbalance,geneticsusceptibilityandesophagealepitheliallesions,animportantroleinoccurrenceanddevelopmentofesophagus[7].
4.2Cancerofthestomach
Gastriccanceristhefirstcancerdeathinthe1970s,themortalityrateof23.9/10(male32.4/10,femaleof15.9/10),higherleveloftheworld[3].Theoccurrenceofgastriccancer,besidesofsomeofthesameriskfactorswithesophagealpathogenicmicroorganisminfectionisalsoanimportantreason.Studieshaveshownthatgastriccancerinpatientswithhelicobacterpylori(HP)infectionratesashighas94%.GastriccancerhighincidencepopulationHPinfectionrateishigh,theHPantibodypositivepopulationriskofdevelopinggastriccancerwashigherthanthenegative.Carcinogenicmechanism,HPinfectioncausedbyinflammation,injury,inflammation,freeradicals,superoxidegenerationincreases,causecellperoxidationdamage,produceavarietyofenzymesandtoxincellDNAdamagecausedbydirecteffect,andreducethegastricacidsecretion,gastriccavitypHvalueincreases,forbacterialandfungalreproductivegrowth,thenitritewithN-nitrosocompoundandotherimportantcarcinogenssynthesisinthestomach.HPpersistentinfectioningastricmucosametabolicchanges,graduallypromotethegastricepithelialhyperplasia,intestinalmetaplasiaandatypicalhyperplasiathatturnintocancer.
Henanlinzhougastriccancerincidenceofadiseasealsobelongtoahigherlevelthroughoutthecountry.1988-Linzhoucitygastriccancerincidenceandmortalityin2007,showedatrendofgradualdecline(figure1),Linzhoucityofesophagealcancerincidenceandmortalitycomparedwithsimilarchanges[9].InLinIngastriccancerincidenceandmortalityfromallreducedto60.3/79.1/10and59.7/10.10and43.6/10,reducedthe18.8/10and16.1/10,declines24%and27%.
Fig.1IncidenceandmortalityofstomachcancerinLinzhoucity,1988-2007
3.3livercancer
Livercanceristhethirdcancerdeathsinthe1970s,themortalityrateof14.0/10(20.2/10men;womenof8.1/10),higherleveloftheworld[3].LivercancerisacommoncancerChinaeastChinaarea.Qidongcity,jiangsuprovinceofChinaoneofthehighincidenceoflivercancer,researchshowsthatseparatesthelivercancerandaflatoxincontaminationoffood,spreadofhepatitisbandcarcinogenicsubstancespollutedwater.Qidongregionandducklivercancerratesarehigh,itsetiologymaybesimilarto[8].
4.4Cervicalcancer
CervicalcancerisoneofthemostcommoncanceroftheChinesewomeninthe1970s,cervicalcanceraccountsforChina'sfemalecancerthefirstcauseofdeath,mortalityrateof14.6/10,21%ofthefemalecancerdeath[3],ahighleveloftheworld.Pathogenicmicroorganismsreferstoinfringementofthehost,thehostinfectionorinfectiousorganisms.Pathogenicmicroorganismshasimportanteffecttocervicalcancerincidence,closerrelationshipwithcervicalcancerincidenceismainlyviruses,includingthehumanpapillomavirus(HPV),he