LCV scores in the HouseSenate rose with per capita incomeWord格式文档下载.docx

LCV scores in the HouseSenate rose with per capita incomeWord格式文档下载.docx

《LCV scores in the HouseSenate rose with per capita incomeWord格式文档下载.docx》由会员分享，可在线阅读，更多相关《LCV scores in the HouseSenate rose with per capita incomeWord格式文档下载.docx（26页珍藏版）》请在冰豆网上搜索。

Purchase

$41.95

891

Roleofgenderandlinguisticdiversityinworddecodingdevelopment 

LearningandIndividualDifferences,InPress,CorrectedProof,Availableonline26February2011

LudoVerhoeven,JanvanLeeuwe

Closepreview 

LOADING....

$37.95

ResearchHighlights

►GirlsarebetterinDutchworddecodingthroughouttheprimarygrades.►SecondlanguagelearnersstaybehindindecodingcomplexDutchwords.►Thereisnointeractionbetweengenderandlinguisticdiversityonworddecoding.►Thestructureofworddecodingdevelopmentishighlysimilaracrossgroups.

892

AShapeOptimizationMethodforNonlinearAxisymmetricMagnetostaticsUsingaCouplingofFiniteandBoundaryElements 

MathematicsandComputersinSimulation,InPress,AcceptedManuscript,Availableonline26February2011

D.Luká

š,K.Postava,O.Životský

AbstractAbstract

Abstract

Inthispaperweproposeamethodforconstrainedshapeoptimizationgovernedwithanonlinearaxisymmetricmagnetostaticstateproblemandweapplyittoanoptimalshapedesignofanelectromagnet.ThestateproblemissolvedviaHiptmair'

ssymmetriccouplingoffiniteelementsemployedintheinteriorferromagneticdomainandboundaryelementsmodellingtheexteriorairdomainaswellascurrentexcitations.AsanoveltywederiveDuffyregularizationtransformsoftheboundaryelementintegralsfortheaxisymmetriccase,whicharethenevaluatedusingatensor–productGaussianquadrature.NonlinearferromagneticbehaviourisresolvedbyNewtoniterations.Theoptimizationmethodunderbothlinearandnonlinearconstraintsreliesontheactive–setsteepest–descentsearch,projectionsontothesetoflinearizedconstraints,andanadjointmethodofshapesensitivityanalysis.Shapeperturbationsinfluencegriddeformationviaasolutiontoanauxiliarytorsion–freelinearelasticityproblem.Finally,numericalresultsarepresented.

$31.50

893

Designandvalidationofabi-axialloadingbioreactorformechanicalstimulationofengineeredcartilage 

MedicalEngineering&

Physics,InPress,CorrectedProof,Availableonline26February2011

NorwahidaYusoff,NoorAzuanAbuOsman,BelindaPingguan-Murphy

AbstractAbstract|Figures/TablesFigures/Tables|ReferencesReferences

Amechanical-conditioningbioreactorhasbeendevelopedtoprovidebi-axialloadingtothree-dimensional（3D）tissueconstructswithinahighlycontrolledenvironment.Thecomputer-controlledbioreactoriscapableofapplyingaxialcompressiveandsheardeformations,individuallyorsimultaneouslyatvariousregimesofstrainandfrequency.Thereliabilityandreproducibilityofthesystemwereverifiedthroughvalidationofthespatialandtemporalaccuracyofplatenmovement,whichwasmaintainedovertheoperatinglengthofthesystem.Inthepresenceofactualspecimens,thesystemwasverifiedtobeabletodeliverprecisebi-axialloadtothespecimens,inwhichthedeformationofeveryspecimenwasobservedtoberelativelyhomogeneous.Theprimaryuseofthebioreactorisinthecultureofchondrocytesseededwithinanagarosehydrogelwhilesubjectedtophysiologicalcompressiveandsheardeformation.Thesystemhasbeendesignedspecificallytopermittherepeatablequantificationandcharacterisationofthebiosyntheticactivityofcellsinresponsetoawiderangeofshortandlongtermmulti-dimensionalloadingregimes.

ArticleOutline

1.Introduction

2.Bi-axialloadingbioreactor

2.1.Finiteelementmodeling

2.2.Designanddescription

2.2.1.Mediumtransfer

2.2.2.Controlsystem

3.Validationtests

3.1.Platendisplacement

3.2.Platenfrequency

3.3.Consistencyofplatenmovementandstabilityoflong-termoperation

3.4.Validationofagarosedeformation

4.Discussion

5.Conclusion

Conflictofinterest

Acknowledgements

References

894

TheSingaporehighresolutionsinglecellimagingfacility 

NuclearInstrumentsandMethodsinPhysicsResearchSectionB:

BeamInteractionswithMaterialsandAtoms,InPress,CorrectedProof,Availableonline26February2011

FrankWatt,XiaoChen,ArminBaysicDeVera,ChammikaCNUdalagama,RenMinqin,JeroenAvanKan,AndrewABettiol

TheCentreforIonBeamApplications,NationalUniversityofSingaporehasrecentlyexpandedfromthreestate-of-the-artbeamlinestofive.Twonewbeamlineshavebeenconstructed:

Asecondgenerationprotonbeamwritingline,andahighresolutionsinglecellimagingfacility.BothsystemsfeaturehighdemagnificationlenssystemsbasedoncompactOxfordMicrobeamsOM52lenses,coupledwithreducedlens/imagedistances.

ThesinglecellimagingfacilityisdesignedaroundOM52compactlensescapableofoperatinginavarietyofhighdemagnificationconfigurationsincludingthespacedOxfordtripletandthedoublecrossoverRussianquadruplet.Thenewfacilityhasdesignspecificationsaimedatspatialresolutionsbelow50 

nm,withavarietyoftechniquesincludingSTIM,secondaryelectronandfluorescenceimaging,andanin-builtopticalandfluorescencemicroscopeforsampleimaging,identificationandpositioning.

PreliminarytestsusingthesinglespaceOxfordtripletconfigurationhaveindicatedabeamspotsizeof31 

×

39 

nminthehorizontalandverticaldirectionsrespectively,atbeamcurrentsof

10,000protonspersecond.However,aweaknessinthespecificationsoftheelectrostaticscanningsystemhasbeenidentified,andamorestablescanningsystemneedstobeimplementedbeforewecanfullyrealizetheoptimumperformance.Asinglewholefibroblastcellhasbeenscannedusing1.5 

MeVprotons,andamedianfittotheprotontransmissionenergylossdatahasshownthatprotonSTIMgivesexcellentdetailsofthecellstructuredespitetherelativelypoorcontrastofprotonSTIMcomparedwithalphaSTIM.

2.Descriptionofthehighresolutionsinglecellimagingfacility

3.Preliminarytestsofthehighresolutionsinglecellimagingfacility

4.Discussionandconcludingremarks

$39.95

895

Quantitativegeneticstudyofamphiregulinandfractalkinecirculatinglevels–potentialmarkersofarthropathies 

OsteoarthritisandCartilage,InPress,CorrectedProof,Availableonline26February2011

A.Leonov,S.Trofimov,S.Ermakov,G.Livshits

Supplementarycontent 

Summary

Objective

Amphiregulin（AREG）andFractalkine（FRACT）,areinvolvedinavarietyofnormalandpathologicalprocesses,andarebothsuggestedtoberelevanttojointdegeneration.Theaimsofthepresentstudyincluded

（1）testingassociationbetweencirculatinglevelsofthesebiomarkersandjointpathologies,

（2）evaluationoftheputativegeneticandfamilialfactors’effectonAREGandFRACTvariability.

Design

Thestudywasconductedinthefamily-basedsampleof923Caucasianindividuals.VariancecomponentanalysiswasusedtoassesscontributionofgeneticandenvironmentalfactorstovariabilityofAREGandFRACTconcentration.

Results

ThemeanlevelsofFRACTweresignificantlyhigherintheaffectedgroupwitharthropathies（synovialjointsosteoarthritis（OA）anddiscdegenerativedisease,DDD）theninthecontrolgroup（P 

<

0.0004）.CirculatingAREGlevelswerehigherinDDD（P 

= 

0.0272）.GeneticfactorsconstitutedthemainsourceoftheinterindividualdifferencesoftheAREGandFRACTlevelsinoursample,andexplained29.68%and41.68%ofthetotalvariation,respectively.ThephenotypiccorrelationbetweenAREGandFRACTwassubstantial（r 

0.55,P 

0.0001）andwasassociatedwithbothcommongeneticandenvironmentalfactors.Specifically,30%ofthephenotypiccorrelationbetweenAREGandFRACTwasduetocommongeneticeffects.

Conclusions

FurtherstudiesarerequiredtoassessrelevancyofFRACTtoclinicaldiagnosisandprognosisofarthropathies,toinvestigatethemechanismsbehindtheobservedphenotypicandgeneticcovariationamongthestudiedbiomarkers,andtoexplorespecificgeneticpolymorphismsaffectingAREGandFRACTvariation.

Introduction

Materialsandmethods

Sample

Biochemicalmeasurements

Statisticalanalysis

Results

Preliminarystatisticsforbiochemicalmarkers

Quantitativegeneticanalysis

Discussion

Authorcontributions

Competinginterests

AppendixSupplementarymaterial

896

Discoveringandrestoringchangesinobjectpositionsusinganautonomousrobotwithlaserrangefinders 

RoboticsandAutonomousSystems,InPress,CorrectedProof,Availableonline26February2011

FredyTungadi,LindsayKleeman

AbstractAb