杏芎氯化钠注射液治疗急性脑梗塞32例临床观察Word文档下载推荐.docx

杏芎氯化钠注射液治疗急性脑梗塞32例临床观察Word文档下载推荐.docx

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方法将62例急性脑梗塞患者随机分成治疗组和对照组。

两组常规治疗方法相同。

治疗组给予杏芎氯化钠注射液1次/d，静脉滴注；

对照组加丹奥注射液、克林澳注射液2次/d，静脉滴注，脑细胞活化剂特安欣（肌氨肽苷）注射液1次/d，静脉滴注，2周后观察疗效。

结果治疗组与对照组的总有效率分别为%和%（）,显效率分别为%、%（），均无显着性差异。

治疗组在改善神经功能缺损方面明显好于对照组（）。

结论杏芎氯化钠注射液治疗急性脑梗塞具有多种治疗作用，用药简便、疗效确切，而且在改善神经功能缺损方面作用较好，值得临床推广应用。

【关键词】杏芎氯化钠注射液；

急性脑梗塞；

临床疗效

　　Abstract:

ObjectiveToobservethetherapeuticeffectofFloiumGinkgoextractandTertramEthypyrazinesodiumchlorideinjectiononacutecerebraltwocasesofpatientswithacutecerebralinfarctionweredividedintotwogroupsatrandom,treatmentgroup（32cases）andcontrolgroup（30cases）.Bothofthegroupsweretreatedwiththesameordinary　casesofthetreatmentgroupweregivenFloiumGinkgoextractandTertramEthypyrazinesodiumchlorideinjectionqd,ivgtt.ThecasesofthecontrolgroupweregivensodiumOzagrel,CinepazideMaleateinjection,bid,ivgtt.andMuscularAminoAcidsandPeptidesandNucleosidesInjectiontoobservetheefficacy.Thetreatmentcoursewas2　wasnosignificantdifferencebetweentwogroups.Thetotaleffectiverateinthetreatmentgroupandthecontrolgroupwas%and%respectively（）andtheexcellenteffectiveratewas%and%respectively（）.Theneurologicalfunctiondefectscoringinthetreatmentgroupwassignificantlybetterthanthatofinthecontrolgroup（）.ConclusionBecauseFloiumGinkgoextractandTertramEthypyrazinesodiumchlorideinjectioniseasilyusedandhasacocktailpositiveeffectonmanykindsoftreatmentactionandimprovementofneurologicalfunctiondefectinclinic,itisworthbeingpopularizedandusedclinically.

　　KeywordsFloiumGinkgoextractandTertramEthypyrazinesodiumchlorideinjection,Acutecerebralinfarction,Curativeeffect

　　Cerebralinfarctionisalsocalledischemiabrainstroke,acommonandfrequentcerebrovasculardiseaseinclinic,itisthethirdleadingcauseofdeathinallkindsofdiseaseinmiddle-agedpopulationinclinicwithhighmorbiditymortalityanddisability.Inrecentyearsacutecerebralinfarctionisincreasingtendtoyoung［1］，atpresentnosinglewesternagentcancureiteffectively,butFloiumGinkgoextractandTertramEthypyrazinesodiumchlorideinjectioncandoit.Itwillexpandanewtrainofthoughtandopenwidelyfieldofvisionbecauseitcontainsavarietyofmoleculeswithpotentbiologicalactivitiesandacocktailtherapeuticmethodtocureacutecerebralinfarction,butthedrughasn‘tbeenusedforalongperiodoftime,wewillobserveitsefficacyinclinicinordertofurtherinvestigatetherapeuticeffect.

　　1ClinicalMaterial

　　Allthecasesweredividedrandomlyintotreatmentgroup（32cases）andcontrolgroup（30cases）from62consecutiveacutecerebralinfarctionpatientsadmittedtoourhospital.Diagnosisofacutecerebralinfarctionforeachcasewasmadeaccordingtostandardofcerebralinfarctiondiagnosisandbraincomputedtomography（CT）and/ormagneticresonanceimages（MRI）wereusedtoconfirmthediagnosis.Patientswithcerebralhemorrhage,liverdisfunction,renaldisfunction,cardiovasculardiseasesandhematologicaldiseaseswereexcluded.

　　Therewasnosignificantdifferencebetweentwogroupsinages,sexes,symptoms,scoresofneurologicalfunctiondefectandordinarymethodbeforethepatientsadmittedtohospitalbystatisticalanalysis.

　　StandardofdiagnosisDiagnosisofacutecerebralinfarctionwasmadeaccordingtotheChineseneurologicalacademyaboutessentialsofdiagnosisoneachkindofcerebrovasculardisease［2］.Braincomputedtomography（CT）and/ormagneticresonanceimages（MRI）wereusedtoconfirmthediagnosis.

　　Tab1Comparisonofgeneralconditionsinthetwogroups

　　Clinicalsymptomsofacutecerebralinfarctionoftensuddenlytroublestandingorwalking,speakingorunderstanding,seeingwithoneorbotheyesanddizziness,lossofbalanceorcoordination,numbnessoftheface,armorlegweakness,especiallyononesideofthebody,severeheadacheswithnoknowncause,brieflossofconsciousnessoraperiodofdecreasedconsciousness（fainting,confusion,convulsionsorevencoma）.

　　2TherapeuticMethods

　　Theordinarymethod:

thecaseswithhypertensionwasgivenanti-hypertension［3］，withhyperglycemiagivenanti-hyperglycemia,withhighlipidgivenlowingbloodlipid,hydrocephalus,andoxygenation,radiotherapyaccordingtotheconcreteconditionsofacutecerebralinfarction.

　　ThetreatmentgroupwasgivenFloiumGinkgoextractandTertramEthypyrazinesodiumchlorideinjection100～250ml,qd,iv　controlgroupwasgivensodiumOzagrel160mg,CinepazideMaleate160mginjectionaddto%NaCl,bid,ivgttandMuscularAminoAcidsandPeptidesandNucleosides10mlInjectionqd,ivgtt.Thetreatmentcoursewas2weeks.

　　Statisticalanalysesweremadeusingthetargetofneurologicalfunctiondefectscorningandclinicalsympto